Heather Davies
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Infective Endocarditis Diagnosis and Management
- Genomics and Rare Diseases
- Antifungal resistance and susceptibility
- Zoonotic diseases and public health
- Data-Driven Disease Surveillance
- Bacterial Identification and Susceptibility Testing
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Advanced biosensing and bioanalysis techniques
- Bacterial Genetics and Biotechnology
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Acute Ischemic Stroke Management
Institute of Environmental Science and Research
2020-2024
Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, which are typically transmitted via respiratory droplets, leading causes of invasive diseases, including bacteraemic pneumonia meningitis, secondary infections subsequent to post-viral disease. The aim this study was investigate the incidence disease due these pathogens during early months COVID-19 pandemic.In prospective analysis surveillance data, laboratories in 26 countries territories across six continents...
BackgroundThe Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and agalactiae. We aimed analyse incidence distribution these during first 2 years compared preceding pandemic.MethodsFor this prospective analysis, laboratories in 30 countries territories representing five continents submitted surveillance data from Jan...
Whooping cough, the respiratory disease caused by Bordetella pertussis , has undergone a wide-spread resurgence over last several decades. Previously, we developed pipeline to assemble repetitive B. genome into closed sequences using hybrid nanopore and Illumina sequencing. Here, this sequencing was used conduct more high-throughput, longitudinal screen of 66 strains isolated between 1982 2018 in New Zealand. Zealand higher incidence whooping cough than many other countries; usually at least...
A loxP-transposon retrofitting strategy for generating large nested deletions from one end of the insert DNA in bacterial artificial chromosomes and P1 was described recently [Chatterjee, P. K. & Coren, J. S. (1997) Nucleic Acids Res. 25, 2205-2212]. In this report, we combine procedure with direct sequencing nested-deletion templates by using primers located transposon to illustrate its value position-specific single-nucleotide polymorphism (SNP) discovery chosen regions clones. simple...
Abstract Background Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis are leading causes of invasive diseases including bacteraemic pneumonia meningitis, secondary infections post-viral respiratory disease. They typically transmitted via droplets. We investigated rates disease due to these pathogens during the early phase COVID-19 pandemic. Methods Laboratories in 26 countries across six continents submitted data on cases S H N from 1 January 2018 31 May 2020....
Abstract Genomic surveillance is an essential part of effective disease control, enabling identification emerging and expanding strains monitoring subsequent interventions. Whole-genome sequencing was used to analyze the genomic diversity all Neisseria meningitidis isolates submitted New Zealand Meningococcal Reference Laboratory during 2013–2018. Of 347 for whole-genome sequencing, we identified 68 sequence types belonging 18 clonal complexes (CC). The predominant CC CC41/44; next in...
Summary Background The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis and agalactiae . Here we analyse incidence distribution disease during first two years pandemic. Methods Laboratories in 30 countries/territories representing five continents submitted case data from 2018-2021 private projects within databases...
2. Abstract Whooping cough, the respiratory disease caused by Bordetella pertussis , has undergone a wide-spread resurgence over last several decades. Previously, we developed pipeline to assemble repetitive B. genome into closed sequences using hybrid nanopore and Illumina sequencing. Here, this sequencing was used conduct more high-throughput, longitudinal screen of 66 strains isolated between 1982 2018 in New Zealand. Zealand higher incidence whooping cough than many other countries;...