A5043518829- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Bacterial Genetics and Biotechnology
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Biochemical and Structural Characterization
- Enterobacteriaceae and Cronobacter Research
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Gut microbiota and health
- Infections and bacterial resistance
- Bacteriophages and microbial interactions
- Vibrio bacteria research studies
- Criminal Justice and Penology
- Spondyloarthritis Studies and Treatments
- RNA and protein synthesis mechanisms
- Therapeutic Uses of Natural Elements
- Social Issues and Policies in Latin America
- Pneumonia and Respiratory Infections
- Plant Pathogenic Bacteria Studies
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
Universidad El Bosque
2013-2024
Hospital Militar Central
2023
Institute of Genetics and Cancer
2021
Western General Hospital
2021
University of Edinburgh
2021
Edinburgh Royal Infirmary
2021
Roslin Institute
2021
Universidad Mayor
2019
Diego Portales University
2015-2018
Hospital Oncológico Docente "Conrado Benítez García"
2015
ABSTRACT Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed all of the isolates harbored bla NDM-1 , qnrA and intI1 genes clonally related. Multilocus sequence typing belonged to new type (ST1043) was different types had previously been reported. This is first report South America.
Bacteria that produce the broad-spectrum Carbapenem antibiotic New Delhi Metallo-β-lactamase (NDM) place a burden on health care systems worldwide, due to limited treatment options for infections caused by them and rapid global spread of this resistance mechanism. Although it is believed associated gene blaNDM-1 originated in Acinetobacter spp., role Enterobacteriaceae its dissemination remains unclear. In study, we used whole genome sequencing investigate dynamics blaNDM-1-positive plasmids...
The study develops a Contextualized Learning Resource Material (C-LRM) incorporating the Local Ecological Knowledge (LEK) in learning process to develop active information and long-term knowledge. flora fauna of species specific areas like Mt. Agad have enormous importance for ecological forests, relationships between biological things that are currently existence as well those relationships. However, more students missing benefits environmental awareness lends itself promoting responsible...
Las Instituciones de Educación Superior (IES) tienen el reto la formación integral del profesional glocal Siglo XXI a través desarrollo conocimientos y competencias globales, logrando resultados aprendizaje en un contexto interdisciplinario, multicultural e internacional como ciudadanos mundo, profesionales integrales con identidad cultural, comprometidos sostenible mejoramiento calidad vida sociedad. El curricular responde las mega-tendencias nueva globalización, analizando necesidades para...
As a first national surveillance of Acinetobacter in Cuba, total 500 spp. isolates recovered from 30 hospitals between 2010 and 2012 were studied. baumannii-calcoaceticus complex accounted for 96.4% all the isolates, while other species detected at low frequency (A. junii 1.6%, A. lwoffii 1%, haemolyticus 0.8%, soli 0.2%). Resistance rates 34-61% to third-generation cephalosporins, 49-50% β-lactams/inhibitor combinations, 42-47% aminoglycosides, 42-44% carbapenems 55% ciprofloxacin. However,...
Pseudomonas aeruginosa Sequence Type 235 is a clone that possesses an extraordinary ability to acquire mobile genetic elements and has been associated with the spread of resistance genes, including genes encode for carbapenemases. Here, we aim characterize platforms involved in dissemination blaKPC-2-positive P. ST235 Colombia. In prospective surveillance study infections adult patients attended five ICUs distant cities Colombia, 58 isolates were recovered, which, 27 (46.6%) resistant...
A survey on cryptococcosis is being conducted regularly in Colombia since 1997. We present hereby the results corresponding to patients diagnosed from 2006 2010.To analyze data obtained during this period.Retrospective analysis of surveys.A total 526 surveys originating 72% Colombian political divisions were received 5-year period. Most (76.6%) males and 74.9% 21-50 years old. The most prevalent risk factor was HIV infection (83.5%) with defining AIDS 23% cases. In general population...
Abstract The study of the GI-tract microbiota spondylarthritis (SpA) patients has focused on analysis feces samples, that picture mostly luminal microbiota. aim this was to determine contribution mucosal and microbiome gut dysbiosis in SpA, using colonoscopy aspiration lavages (CAL), a recent alternative for regional studies GI-tract. We analyzed 59 CAL (from sigmoid colon distal ileum), 41 from 32 SpA 7 healthy individuals, 16S rRNA gene-targeted metataxonomic profiling. It found high...
Journal Article Isolation of Rabies Virus Outside the Human Central Nervous System Get access Alvaro Dueñas, Dueñas Search for other works by this author on: Oxford Academic PubMed Google Scholar Mark A. Betsey, Betsey Jorge Escobar, Escobar Pablo Medina, Medina Carlos Sanmartin The Infectious Diseases, Volume 127, Issue 6, June 1973, Pages 702–704, https://doi.org/10.1093/infdis/127.6.702 Published: 01 1973 history Received: 09 August 1972 Revision received: 13 November
Introduction. Methicillin-resistant Staphylococcus aureus (MRSA) cause nosocomial and community infections. MRSA colonization in hospitals has been described as an important risk factor during hospitalization.Objective. The characteristics of was using the tools molecular biology.Materials methods. Between February 2007 2008, 705 patients entering a Colombian intensive care unit (ICU) were screened for by taking nasopharyngeal samples. For 683 these patients, weekly follow-up provided after...
Community-genotype methicillin-resistant Staphylococcus aureus (CG-MRSA) isolates are known to be more virulent and clinically aggressive in children. The goal of the present study was characterize molecular epidemiology MRSA causing infections Colombian children.An observational prospective conducted between April 2009 June 2011 at 15 hospitals Bogotá, Colombia. A detailed epidemiological profile made 162 children infected with MRSA. were subjected antimicrobial susceptibility testing,...
Pseudomonas aeruginosa, a bacterium commonly isolated from hospital settings, exhibits intrinsic resistance to number of antibiotics and can acquire during antibiotic therapy. Resistance towards carbapenems is increasing due its overuse in the treatment infections caused by extended-spectrum β-lactamase (ESBL) producing organisms. Nonetheless, are essential for high-risk one remaining weapons fight against "extreme drug resistance" Gram-negative/positive bacilli. Herein, we describe case...
Abstract Resistance to carbapenems in Klebsiella pneumoniae has been mostly related with the worldwide dissemination of KPC, largely due pandemic clones belonging complex clonal (CC) 258. To unravel bla KPC post-endemic clinical impact, here we describe characteristics 68 patients from a high complexity hospital, and molecular genetic their 139 — K. (KPC- Kp ) isolates. Of 26 that presented relapses or reinfections, 16 had changes resistance profiles isolates recovered recurrent episodes. In...
Providencia rettgeri is an opportunistic bacterial pathogen of clinical significance due to its association with urinary tract infections and multidrug resistance. Here, we report the first complete genome sequence P. The strain RB151 consists a 4.8-Mbp chromosome 108-kbp blaNDM-1-positive plasmid.
Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of "old" antibiotics such as polymyxin B and E (colistin). However, there is concern regarding emergence isolates resistant to these antibiotics. We report case 64-year-old mestizo man hospitalized in an intensive care unit institution Colombia with identification clinical molecular typing colistin- carbapenem-resistant A. isolate mechanisms resistance colistin not...
The dissemination of a clone community genotype methicillin-resistant Staphylococcus aureus (CG-MRSA) that is related to USA300 has been reported in Latin America. We recently detected isolates new CG-MRSA (spa type t1635 and ACME-negative) was genetically unrelated the causes infections children Colombia. This finding indicates appearance our region.
Positive Deviance (PD) is a process to achieve social and cultural change. This strategy has been used for the control of methicillin-resistant Staphylococcus aureus (MRSA) infection in some health institutions United States, but rarely adopted from developing countries where resources are limited. We describe our experience PD healthcare-associated infections (HAIs) due MRSA Colombian hospital with aim reducing HAI rates through change processes. A time-series study was conducted based on...
The carbapenemase OXA-244 is a derivate of OXA-48, and its detection very difficult in laboratories. Here, we report the identification genomic analysis an Escherichia coli isolate (28Eco12) harboring blaOXA-244 gene identified Colombia, South America. 28Eco12 was during retrospective study, it recovered from patient treated Colombia. complete nucleotide sequence established using PacBio platform. A comparative genomics with other blaOXA-244-harboring strains performed. belonged to type (ST)...
Introduction: One of the major worldwide public health problems today are infections caused by carbapenem-resistant Enterobacteriaceae (CRE), among which Klebsiella pneumoniae (CRKP), constitutes one most common pathogens causing nosocomial infection.Objective: This study was aimed at describing dissemination KPC-3 enzyme-producing in clinical isolates from hospitals Bogotá.Materials and methods: Eighty-two CRKP collected 10 Bogota 2008-2010 were analysed; disk diffusion microdilution used...
USA300 is a genetic lineage found both in methicillin-resistant (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) isolates. In Colombia, hospital community MRSA infections are caused by USA300-related genotype (CG-MRSA) clone. The origin of this clone unknown yet. To identify characterize S. isolates order to improve the information about CG-MRSA Colombia. MSSA were detected characterized from study 184 (90 94 MSSA) recovered infections. relatedness was established means pulsed...