A5102912917- Tuberculosis Research and Epidemiology
- Cancer Genomics and Diagnostics
- Diagnosis and treatment of tuberculosis
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Molecular Biology Techniques and Applications
- Hematological disorders and diagnostics
- RNA modifications and cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Genital Health and Disease
- Infective Endocarditis Diagnosis and Management
- Dermatological diseases and infestations
- Organic Food and Agriculture
- Pericarditis and Cardiac Tamponade
- Ear and Head Tumors
- Yeasts and Rust Fungi Studies
- Blood donation and transfusion practices
- Sexual Differentiation and Disorders
- Wine Industry and Tourism
- Maternal and fetal healthcare
- Lung Cancer Research Studies
- Health, Environment, Cognitive Aging
Universidad Nacional Autónoma de México
2023
Baylor College of Medicine
2023
The University of Texas Health Science Center at San Antonio
2023
The University of Texas Health Science Center at Houston
2023
Fundación Santa Fe de Bogotá
2009-2022
Universidad Nacional de Colombia
1998-2021
Universidad de Los Andes
2019-2021
Pasqual Maragall Foundation
2019
National Institutes of Health
2001
National Cancer Institute
2001
Infiltrating pleomorphic lobular carcinoma (PLC) is an aggressive variant of infiltrating carcinoma. Recently, in situ changes identical to PLC (PLCIS) have been described. The role prognostic markers and their correlation with therapeutics, clinical outcome, genetic not well established PLC. authors examined 38 cases this entity understand better tumor's biology. Immunohistochemical (IHC) analysis was performed 21 specimens for estrogen progesterone steroid receptors, p53, Her 2 (p185),...
Although high-risk human papillomaviruses (HPVs) are an important risk factor in the etiopathogenesis of cervical cancer, increasing evidence suggests that ability to avoid immune surveillance seems be linked transforming potential HPV and a rapid progression cancer. In other cancer models, IL-10 contributes impair anti-tumor response either by downregulating leukocyte antigen Class I (HLA-I) expression or HLA-G expression. To comprehend how these alterations could contribute evasion we...
Abstract Resistance to carbapenems in Klebsiella pneumoniae has been mostly related with the worldwide dissemination of KPC, largely due pandemic clones belonging complex clonal (CC) 258. To unravel bla KPC post-endemic clinical impact, here we describe characteristics 68 patients from a high complexity hospital, and molecular genetic their 139 — K. (KPC- Kp ) isolates. Of 26 that presented relapses or reinfections, 16 had changes resistance profiles isolates recovered recurrent episodes. In...
Cancer patients have an increased risk of reactivation latent tuberculosis infection. It is unknown which strategy on screening should be used in this population developing countries. We aimed to determine the concordance between tuberculin skin test (TST) and QuantiFERON ® -TB (QFT) assay order diagnose infection cancer patients. conducted a cross-sectional study agreement diagnostic tests. Prevalence tests were calculated. A logistic regression assess predictors discordance was performed....
Loss of heterozygosity (LOH) at the 3p region is found in up to 50% epithelial ovarian neoplasms. The von Hippel-Lindau (VHL) gene 3p25 locus one tumor-suppressor genes located 3p. role, if any, VHL not clear carcinogenesis. We analyzed primary and metastatic clear-cell carcinomas (OCCC) for LOH determine its frequency diagnostic utility as an adjunctive tool differential diagnosis carcinomas. Microdissection followed by single-step DNA extraction polymerase chain reaction (PCR)...
Primary laryngeal tuberculosis is a rare disease with wide variety of clinical manifestations. We report the case an ear-nose and throat diabetic physician primary tuberculosis. The diagnosis cancer had been considered before in another institution, at patient’s admission, he only presented dysphonia six-month evolution. vocal cord histological examination showed granulomas, giant cells, fibrosis necrosis, Ziehl-Neelsen staining acid-alcohol resistant bacilli. culture from tissue was...
Tuberculous pericarditis is an infrequent but serious form of tuberculosis.Its diagnosis difficult and often delayed or not even reached, which results in complications such as constrictive with high mortality rates (1).In 2017, there were 10 million cases active tuberculosis worldwide 1.3 related deaths making the leading cause death by a single pathogen (2).In Colombia, 13,626 new reported during 2016 83% (11,338 cases) corresponded to pulmonary 17% (2,288 extrapulmonary while 37 (1.6%)...
A peri-clitoral abscess is a condition that seldom encountered in practice and found scarcely the literature. The cause of spontaneous not associated with female circumcision/genital mutilation generally unknown. Additionally, there have been no case reports positive Actinomyces culture at time drainage abscess. This outlines 42-year-old was initially treated incision (I&D) antibiotics, but it later reoccurred necessitating second I&D bedside marsupialization antibiotics targeted...
The increase in the number of gene copies at specific loci is a genetic alteration frequently associated with over expression related protein cancer cells. Genes whose dose consistently augmented include those involved cell cycle control, proliferation, apoptosis, and angiogenesis among others. In this study, onc ogenes MYCL1, MYCN, MYC, EGFR, ERBB2 AKT2 DNA obtained from lung tissue blood plasma, patients primary was evaluated respect to normal plasma healthy individ uals, determine...
1,839 autopsy protocols from the San Juan de Dios Hospitalwere revised, 155 patients had been exposed to smoke, of whom 103 (5.6%) met inclusion criteria. 97% were women. The principal histological changes were: hypertensive vascular disease (39%), pulmonary thrombo-embolism small and rnedium calibre vessels (38%) peribronchial, perivascular interstitial anthracosis. In al1 parameters, greater compromise was seen in relation exposure firewood smoke. spite these peculiar characteristics, it...
Introduction: Worldwide, three people die of tuberculosis (TB) every minute. The risk TB transmission among healthcare workers is up to 40 times higher than in the general population. Nevertheless, Colombia, little importance has been given this situation. Objective: To describe demographic and clinical characteristics with treated a university hospital from Bogotá D.C. (Colombia), as well their laboratory, histologic, imaging findings, main criteria for diagnosis. Materials methods: Case...