Leonardo F. Jurado

ORCID: 0000-0003-2565-808X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Tuberculosis Research and Epidemiology
  • Diagnosis and treatment of tuberculosis
  • Infectious Diseases and Tuberculosis
  • Immune responses and vaccinations
  • Immune cells in cancer
  • Mycobacterium research and diagnosis
  • Immune Response and Inflammation
  • Dermatological diseases and infestations
  • Mollusks and Parasites Studies
  • Myasthenia Gravis and Thymoma
  • Amoebic Infections and Treatments
  • Appendicitis Diagnosis and Management
  • Fungal Infections and Studies
  • Parkinson's Disease and Spinal Disorders
  • Travel-related health issues
  • Immunotherapy and Immune Responses
  • Viral-associated cancers and disorders
  • Renal Transplantation Outcomes and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Syphilis Diagnosis and Treatment
  • Invertebrate Taxonomy and Ecology
  • Antifungal resistance and susceptibility
  • Pericarditis and Cardiac Tamponade
  • Hematological disorders and diagnostics
  • Polyomavirus and related diseases

McGill University Health Centre
2023-2024

McGill University
2020-2024

Universidad Nacional de Colombia
2013-2021

Fundación Santa Fe de Bogotá
2015-2020

Corporación Universitaria del Huila
2016

Summary Mycobacterium bovis BCG is the vaccine against tuberculosis and an immunotherapy for bladder cancer. When administered intravenously, reprograms bone marrow hematopoietic stem progenitor cells (HSPCs), leading to heterologous protection infections. Whether HSPC-reprogramming contributes anti-tumor effects of into unknown. We demonstrate that in both mice humans HSPCs amplify myelopoiesis functionally enhance myeloid cell antigen presentation pathways. Reconstitution naive with from...

10.1101/2024.03.21.586166 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-03-21

Primary laryngeal tuberculosis is a rare disease with wide variety of clinical manifestations. We report the case an ear-nose and throat diabetic physician primary tuberculosis. The diagnosis cancer had been considered before in another institution, at patient’s admission, he only presented dysphonia six-month evolution. vocal cord histological examination showed granulomas, giant cells, fibrosis necrosis, Ziehl-Neelsen staining acid-alcohol resistant bacilli. culture from tissue was...

10.7705/biomedica.v34i1.1624 article EN publisher-specific-oa Biomédica 2013-09-17

Tuberculosis is the single most frequent cause of death by an infectious agent worldwide. Diagnosis extra-pulmonary tuberculosis not always possible through conventional methods, due to long time required for cultures and paucibacillary nature samples; hence need rapid molecular methods. HIV infection increases risk tuberculosis, HIV/tuberculosis coinfection associated with higher mortality.We describe case a 56-year old mestizo male patient suspected having who consulted San Ignacio...

10.7705/biomedica.v35i1.2275 article EN publisher-specific-oa Biomédica 2014-09-03

Tuberculous pericarditis is an infrequent but serious form of tuberculosis.Its diagnosis difficult and often delayed or not even reached, which results in complications such as constrictive with high mortality rates (1).In 2017, there were 10 million cases active tuberculosis worldwide 1.3 related deaths making the leading cause death by a single pathogen (2).In Colombia, 13,626 new reported during 2016 83% (11,338 cases) corresponded to pulmonary 17% (2,288 extrapulmonary while 37 (1.6%)...

10.7705/biomedica.4911 article EN publisher-specific-oa Biomédica 2020-05-01

Each minute, three people die of tuberculosis worldwide. Abdominal is an infrequent but serious form disease and can affect any abdominal organ. Being a health-care worker one the most important risk factors for developing (TB). TB transmission between patients health care-workers has been reported in virtually every country world constitutes big public-health problem. We describe case young female physician whose clinical presentation started with chest pain, initial workup did not show...

10.1016/j.jrid.2020.02.003 article EN Radiology of Infectious Diseases 2019-12-01

Tumor necrosis factor-α (TNF-α) is an important fundamental cytokine during the immune response against cancer and infections such as tuberculosis. This molecule also plays a key pathogenic role in complex difficult-to-treat diseases rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriasis ulcerative colitis. The treatment of these frequently needs TNF-α antagonists, which has been related to increased risk developing tuberculosis, mycoses, other severe infections.We report...

10.7705/biomedica.v38i0.3273 article EN publisher-specific-oa Biomédica 2018-03-15

Tuberculosis is the single most frequent cause of death by an infectious agent worldwide. Diagnosis extra-pulmonary tuberculosis not always possible through conventional methods, due to long time required for cultures and paucibacillary nature samples; hence need rapid molecular methods. HIV infection increases risk tuberculosis, HIV/tuberculosis coinfection associated with higher mortality. We describe case a 56-year old mestizo male patient suspected having who consulted San Ignacio...

10.1590/s0120-41572015000100002 article EN PubMed 2015-07-07

ABSTRACT Alveolar macrophages (AMs) reside in the lower airways and play a crucial role lung health response to sterile inflammation infections. AMs possess remarkable adaptability different environmental challenges that can persist through their memory capacity (trained immunity). β-glucan has been characterized as potent inducer of trained immunity by reprogramming hematopoietic stem cells (HSCs) bone marrow generating innate with enhanced responsiveness. In present study, we show systemic...

10.1101/2024.09.02.610842 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-03

Alveolar macrophages (AMs) reside in the lower airways and play a crucial role lung health response to sterile inflammation infections. AMs possess remarkable adaptability different environmental challenges that can persist through their memory capacity (trained immunity). β-glucan has been characterized as potent inducer of trained immunity by reprogramming hematopoietic stem cells (HSCs) bone marrow generating innate with enhanced responsiveness. In present study, we show systemic...

10.7554/elife.102068 preprint EN 2024-10-02

Alveolar macrophages (AMs) reside in the lower airways and play a crucial role lung health response to sterile inflammation infections. AMs possess remarkable adaptability different environmental challenges that can persist through their memory capacity (trained immunity). β-glucan has been characterized as potent inducer of trained immunity by reprogramming hematopoietic stem cells (HSCs) bone marrow generating innate with enhanced responsiveness. In present study, we show systemic...

10.7554/elife.102068.1 preprint EN 2024-10-02

Centro de Investigación UNINAVARRA-CINA, Fundación Universitaria Navarra, Neiva, ColombiaGrupo MICOBAC-UN, Departamento Microbiología, Facultad Medicina, Universidad Nacional Colombia, Bogotá, D.C., Colombia

10.7705/biomedica.v37i4.3533 article ES publisher-specific-oa Biomédica 2016-10-31

Introduction: Worldwide, three people die of tuberculosis (TB) every minute. The risk TB transmission among healthcare workers is up to 40 times higher than in the general population. Nevertheless, Colombia, little importance has been given this situation. Objective: To describe demographic and clinical characteristics with treated a university hospital from Bogotá D.C. (Colombia), as well their laboratory, histologic, imaging findings, main criteria for diagnosis. Materials methods: Case...

10.15446/revfacmed.v70n1.90501 article EN cc-by Revista de la Facultad de Medicina 2021-05-03

10.7705/biomedica.v36i3.3617 article ES DOAJ (DOAJ: Directory of Open Access Journals) 2016-09-01

<b>Introduction:</b> Acute respiratory distress syndrome is responsible for 400,000 deaths per year worldwide. Despite five decades of research, no immunomodulatory treatment has been proven to be effective. Trained immunity (TI) the ability innate immune system reprogrammed by a first insult, without persistent inflammation, then providing an increased response second insult. The aim this study confirm that TI could protect from acute lung injury (ALI). <b>Methods:</b> twelve weeks old...

10.1183/13993003.congress-2023.pa4061 article EN 2023-09-09

Introducción. Los trastornos linfoproliferativos después de un trasplante se caracterizan por la proliferación descontrolada linfocitos como consecuencia del tratamiento inmunosupresor posterior a este.Objetivo. Caracterizar clínica y patológicamente los casos (Post-Transplant Lymphoproliferative Disorders, PTLD) en una cohorte pacientes adultos con hígado atendidos lo largo 15 años el Hospital Universitario Fundación Santa Fe Bogotá.Materiales métodos. Se hizo estudio observacional...

10.7705/biomedica.4861 article ES publisher-specific-oa Biomédica 2020-09-24
Coming Soon ...