A5106623539- Antifungal resistance and susceptibility
- Antibiotic Use and Resistance
- Fungal Infections and Studies
- Bacterial Identification and Susceptibility Testing
- Nosocomial Infections in ICU
- Neutropenia and Cancer Infections
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Streptococcal Infections and Treatments
- Public Health and Environmental Issues
- Antibiotics Pharmacokinetics and Efficacy
- Nail Diseases and Treatments
- Toxoplasma gondii Research Studies
- Influenza Virus Research Studies
- Infectious Diseases and Tuberculosis
- Respiratory viral infections research
- Pediatric Urology and Nephrology Studies
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Cytomegalovirus and herpesvirus research
- Neonatal and Maternal Infections
Universidad Nacional de Colombia
2016-2025
Hospital Universitario Nacional de Colombia
2020-2025
Gdańsk Medical University
2023
Viña del Mar University
2018
University of Valparaíso
2018
Hospital Carlos Van Buren
2018
Hospital Luis Calvo Mackenna
2013
University of Chile
2013
University of Cundinamarca
2012
Asociación Colombiana de Infectología
2009
Background The epidemiology of candidemia varies depending on the geographic region. Little is known about in Latin America. Methods We conducted a 24-month laboratory-based survey 20 centers seven American countries. Incidence rates were calculated and was characterized. Results Among 672 episodes candidemia, 297 (44.2%) occurred children (23.7% younger than 1 year), 36.2% adults between 19 60 years old 19.6% elderly patients. overall incidence 1.18 cases per 1,000 admissions, varied across...
The WHO Access, Watch and Reserve (AWaRe) classification has been developed to support countries hospitals in promoting rational use of antibiotics while improving access these essential medicines. We aimed describe patterns worldwide antibiotic according the AWaRe adult inpatient population.The Global Point Prevalence Survey on Antimicrobial Consumption Resistance (Global-PPS) collects hospital data using a standardized PPS methodology. Global-PPS 2015, 2017 2018 data, collected by 664 69...
Abstract Background Severe pneumonia is a common cause of Intensive Care Unit (ICU) admissions. In critically ill patients, identification the pathogen may allow timely adjustment antibiotics and, therefore improve outcomes. The aim this study was to assess whether performing multiplex polymerase chain reaction (PCR) panel in patients with ICU, has any effect on mortality, overall stay, ICU stay and duration antimicrobial therapy. Methods A retrospective cohort conducted adult who required...
The Manual for Surveillance of Events Supposedly Attributable to Vaccination or Immunization in the Region Americas represented one first steps toward building regional system surveillance events supposedly attributable vaccination immunization (ESAVIs) and adverse special interest (AESIs). This manual establishes that, after notification investigation an event, a national committee experts should classify event accordance with World Health Organization (WHO) causality classification. Pan...
Among patients undergoing heart transplantation, Aspergillus is the opportunistic pathogen with highest attributable mortality. The median time of onset from transplantation for invasive pulmonary aspergillosis (IPA) was 46 days, but to first positive culture result 104 days among colonization no disease. Most IPA presented fever and cough within 90 single or multiple nodules. None transplant recipients either extrapulmonary (IEPA) had associated neutropenia. Human leukocyte antigen A1 locus...
Background: Active surveillance is necessary for improving the management and outcomes of patients with candidemia. The aim this study was to describe epidemiologic clinical features candidemia in pediatric Latin America. Method: Prospective, multicenter, a population from 23 hospitals 8 America countries between November 2008 October 2010. Results: Three hundred two cases were reported median incidence 0.81/1000 admissions. Eighty nine (29%) neonates. main risk factors prematurity,...
Candida auris is an emerging pathogen considered to be critical in the World Health Organization fungal organisms list. The study aims determine mortality and hospital stays attributed (C. auris) compared other species adult patients with candidemia. A retrospective cohort of adults candidemia was examined from seven centres Colombia between 2016 2021. primary outcome 30-day mortality, secondary length stay among survivors. Adjustment confounding variables performed using inverse probability...
Background/Objectives: First-generation cephalosporins are used in some countries, primarily Latin America and other low-resource regions, as a first-line or alternative empirical treatment for patients with acute pyelonephritis (AP). This study aimed to evaluate the impact of inappropriate therapy cefazolin on clinical outcomes adult community-acquired AP caused by resistant Enterobacterales, requiring hospitalization two tertiary hospitals Bogotá. Methods: retrospective cohort included...
Background/Objectives: Carbapenem-resistant Enterobacterales (CRE) infection is associated with a higher mortality rate. The purpose of this study was to evaluate the effect ceftazidime avibactam (CZA) for treating bacteremia caused by CRE compared best available therapy in an area where these microorganisms are endemic. Methods: A retrospective cohort patients conducted. We included adults who were treated CZA or (BAT) more than 48 h, and hospitalization time recorded. outcomes death during...
ABSTRACT Introduction The main objective of this study was to evaluate the knowledge, attitudes, and practices physicians related prescription antifungals in a Latin American country. Materials Methods A close survey Colombian physicians' attitudes conducted through an online or paper questionnaire (Fungicap). We performed descriptive analysis sociodemographic variables, which were respondents' medical results. Moreover, exploratory associations between knowledge score characteristics...
In critically ill patients, identification of the pathogen may allow for timely adjustment antibiotics and improved outcomes. Background/Objectives: The aim study was to assess whether performing a multiplex PCR pneumonia panel (PN-panel) in patients with intensive care unit (ICU) had any effect on mortality or other important clinical Methods: A retrospective cohort conducted adult who required ICU admission four institutions Bogotá between November 2019 June 2023. Mortality at 30 days,...
Data with respect to the epidemiological situation of fungal diseases in Colombia is scarce. Thus, aim this study estimate burden infections. A population projection for 2017 from Colombian Department National Statistics was used, as well official information Ministry Health and Institute Health. bibliographical search data on mycotic at risk (chronic obstructive pulmonary disease, HIV infection/AIDS, cancer, transplant patients) done. The estimated 49,291,609 inhabitants, number infections...
The World Health Organization (WHO)'s Research and Development (R&D) Blueprint for Action to Prevent Epidemics, a plan of action, highlighted several infectious diseases as crucial targets prevention. These infections were selected based on thorough assessment factors such transmissibility, infectivity, severity, evolutionary potential. In line with this blueprint, the VACCELERATE Site Network approached disease experts rank listed in WHO R&D according their perceived risk triggering...
Bloodstream infection by Candida species has a high mortality in Latin American countries. The aim of this study was to describe the characteristics patients with documented bloodstream infections caused third level hospitals and determine risk factors for in-hospital-mortality.
Introduction Larger populations at risk, broader use of antibiotics and longer hospital stays have impacted on the incidence Candida sp. bloodstream infections (CBSI). Objective To determine clinical epidemiologic characteristics patients with CBSI in two tertiary care reference medical institutions Mexico City. Design Prospective observational laboratory-based surveillance study conducted from 07/2008 to 06/2010. Methods All were included. Identification antifungal susceptibility performed...
En Colombia, especialmente en las unidades de cuidados intensivos, la candidemia es una causa frecuente infección del torrente sanguíneo y representa el 88 % lasinfecciones fúngicas pacientes hospitalizados, con mortalidad entre 36 78 %. Su incidencia Colombia mayor a reportada los países desarrollados e, incluso, otros Latinoamérica. Para su manejo deben considerarse factores riesgo paciente, luego valorar características clínicas y, finalmente, hacer estudios microbiológicos si necesario,...
Fungemia in hematologic malignancies (HM) has high mortality. This is a retrospective cohort of adult patients with HM and fungemia between 2012 2019 institutions Bogotá, Colombia. The epidemiological, clinical, microbiological characteristics are described, risk factors related to mortality analyzed. One hundred five mean age 48 years (SD 19.0) were identified, 45% acute leukemia 37% lymphomas. In 42%, the was relapsed/refractory, 82% ECOG > 3, 35% received antifungal prophylaxis; 57%...