Paloma Merino Amador
A5060479518- Antifungal resistance and susceptibility
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Fungal Infections and Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 detection and testing
- Clostridium difficile and Clostridium perfringens research
- Spanish Literature and Culture Studies
- Trypanosoma species research and implications
- Microscopic Colitis
- COVID-19 diagnosis using AI
- Cardiovascular Issues in Pregnancy
- Shoulder and Clavicle Injuries
- Latin American Literature Studies
- Gastrointestinal motility and disorders
- Biosensors and Analytical Detection
- Historical and Literary Analyses
- Historical and Modern Theater Studies
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Oral health in cancer treatment
- Pneumonia and Respiratory Infections
- Higher Education Teaching and Evaluation
- Kawasaki Disease and Coronary Complications
Hospital Clínico San Carlos
2007-2024
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2021-2022
Universidad Complutense de Madrid
2020-2022
Instituto de Salud Carlos III
2020
Sistema Nacional de Salud
2020
Candida parapsilosis is a frequent cause of candidemia worldwide. Its incidence associated with the use medical implants, such as central venous catheters or parenteral nutrition. This species has reduced susceptibility to echinocandins, and it susceptible polyenes azoles. Multiple outbreaks caused by fluconazole-nonsusceptible strains have been reported recently. A similar trend observed among C. isolates received in last 2 years at Spanish Mycology Reference Laboratory.Yeast were...
We have been monitoring the antifungal resistance in Candida parapsilosis isolates collected from inpatients at Madrid metropolitan area hospitals for last 3 years. The study aimed to elucidate presence of fluconazole-resistant C. genotypes Madrid. From January 2019 December 2021, a total 354 (n = 346 patients) blood (76.6%) or intraabdominal samples were and genotyped using species-specific microsatellite markers. Antifungal susceptibilities amphotericin B, triazoles, micafungin,...
Abstract Objectives We prospectively monitored the epidemiology and antifungal susceptibility of Candida spp. from blood cultures intra-abdominal samples in patients admitted to hospitals Madrid area. Methods Between 2019 2021, we collected incident isolates [one per species, patient compartment (blood versus samples)] any 16 located Madrid. studied susceptibilities amphotericin B, triazoles, micafungin, anidulafungin ibrexafungerp following EUCAST E.Def 7.3.2 procedure. Results A total 2107...
The World Health Organization (WHO)'s Research and Development (R&D) Blueprint for Action to Prevent Epidemics, a plan of action, highlighted several infectious diseases as crucial targets prevention. These infections were selected based on thorough assessment factors such transmissibility, infectivity, severity, evolutionary potential. In line with this blueprint, the VACCELERATE Site Network approached disease experts rank listed in WHO R&D according their perceived risk triggering...
ABSTRACT We previously conducted a multicenter surveillance study on Candida epidemiology and antifungal resistance in Madrid (CANDIMAD study; 2019–2021), detecting an increase fluconazole-resistant parapsilosis . here present data isolates collected 2022. Furthermore, we report the trends during entire period, including analysis per ward of admission. spp. incident from blood cultures intra-abdominal samples patients cared for at 16 hospitals Madrid, Spain, were tested with EUCAST E.Def...
Summary The aim of the study was to analyse epidemiology and prognosis candidaemia in elderly patients. We performed a comparison clinical presentation according age hazard factors within prospective programme 29 hospitals. One hundred seventy‐six episodes occurred patients (>75 years), 227 middle‐aged (61‐75 years) 232 younger (16‐60 years). Central venous catheter, parenteral nutrition, neutropenia, immunosuppressive therapy caused by Candida parapsilosis were less frequent These...
Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is endemic in Latin-America and emerging Spain due to immigration. The vertical transmission rate around 5%. A routine prenatal screening with serology of all pregnant women from areas recommended identify infected newborns, allowing early treatment cure.The aim this study was estimate the prevalence positive a cohort its transmission.An observational, prospective, follow-up conducted on T. cruzi, as well their January 2013 April 2015....
Abstract The standard RT-PCR assay for COVID-19 is laborious and time-consuming, limiting the availability of testing. Rapid antigen-detection tests are faster less expensive; however, reliability these must be validated before they can used widely. objective this study was to determine Panbio TM Ag Test Device (PanbioRT) (Abbott) SARS-CoV-2 in nasopharyngeal swab specimens. This a prospective multicenter ten Spanish university hospitals patients from hospital units with clinical symptoms or...
Background: Spain is one of the European countries most affected by COVID-19 pandemic. Serological surveys are a valuable tool to assess extent epidemic, given existence asymptomatic cases and limited access diagnostic tests. This nation-wide population-based study aims estimate seroprevalence SARS-CoV-2 infection in at national regional level (province).Methods: Residents 35,893 households were selected from municipal rolls using two-stage random sampling stratified province municipality...
ABSTRACT Background Candida parapsilosis is a frequent cause of candidemia worldwide. Its incidence associated with the use medical implants, such as central venous catheters or parenteral nutrition. This species has reduced susceptibility to echinocandins and susceptible polyenes azoles. Multiple outbreaks caused by fluconazole non-susceptible strains have been reported recently. A similar trend observed among C. isolates received in last two years at Spanish Mycology Reference Laboratory....
Abstract Introduction In patients with inflammatory bowel disease (IBD), Clostridium difficile infection (CDI) is a risk factor for both morbidity and mortality. Currently, appropriate management unclear. Guidance on best practice in the diagnosis treatment of CDI IBD therefore needed. Methods A multidisciplinary group clinicians involved developed 27 consensus statements. Respondents were asked to rate their agreement each statement using 4-point Likert scale. modified Delphi methodology...
Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is endemic in Latin-America and emerging Spain due to immigration. The vertical transmission rate around 5%. A routine prenatal screening with serology of all pregnant women from areas recommended identify infected newborns, allowing early treatment cure. aim this study was estimate the prevalence positive a cohort its transmission. An observational, prospective, follow-up conducted on T. cruzi, as well their January 2013 April 2015....