- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Nosocomial Infections in ICU
- Airway Management and Intubation Techniques
- Transplantation: Methods and Outcomes
- Family and Patient Care in Intensive Care Units
- COVID-19 and Mental Health
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Fungal Infections and Studies
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- COVID-19 and healthcare impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Infant Health and Development
- Pulmonary Hypertension Research and Treatments
- Nail Diseases and Treatments
- Child Nutrition and Feeding Issues
- Hemodynamic Monitoring and Therapy
- Phonocardiography and Auscultation Techniques
- Lysosomal Storage Disorders Research
- Neonatal Respiratory Health Research
- Respiratory viral infections research
Institute of Cardiology
2019-2025
Fundación Neumológica Colombiana
2019-2025
Universidad de Navarra
2019-2024
Infant Foundation
2023
Universidad de La Sabana
2023
Asociación Colombiana de Diabetes
2021
Purpose The COVID-19 pandemic has spread worldwide, and almost 396 million people have been infected around the globe. Latin American countries deeply affected, there is a lack of data in this regard. This study aims to identify clinical characteristics, in-hospital outcomes, factors associated with ICU admission due COVID-19. Furthermore, describe functional status patients at hospital discharge after acute episode Material methods was prospective, multicenter, multinational observational...
Abstract Around one-third of patients diagnosed with COVID-19 develop a severe illness that requires admission to the Intensive Care Unit (ICU). In clinical practice, clinicians have learned admitted ICU due frequently ventilator-associated lower respiratory tract infections (VA-LRTI). This study aims describe characteristics, factors associated VA-LRTI, and its impact on outcomes in COVID-19. was multicentre, observational cohort conducted ten countries Latin America Europe. We included...
Abstract Introduction Determining the optimal timing for extubation in critically ill patients is essential to prevent complications. Predictive models based on Machine Learning (ML) have proven effective anticipating weaning success, thereby improving clinical outcomes. Aim of study The aimed evaluate predictive capacity five ML techniques, both supervised and unsupervised, applied spontaneous breathing trial (SBT), objective cough measurement (OCM), diaphragmatic contraction velocity (DCV)...
Background: Pulmonary hypertension (PH) in patients undergoing lung transplantation (LT) for pulmonary fibrosis can impair function, reduce physical activity, and decrease survival. However, data on outcomes at 1 5 years of follow-up remain limited. Methods: In this prospective cohort study, the 6-min walk test (6MWT), St. George's Respiratory Questionnaire (SGRQ) were assessed pretransplant, hospital discharge, 3, 6, 12 months posttransplant. Additionally, minimal clinically important...
The results of clinical and weaning readiness tests the spontaneous breathing trial (SBT) are used to predict success process extubation.We evaluated capacity cuff leak test, rate rapid shallow breathing, cough intensity, diaphragmatic contraction velocity (DCV) SBT extubation in a prospective, multicenter observational study with consecutive adult patients admitted four intensive care units. We receiver operating characteristic (ROC) curves assess tests' predictive built models using...
The COVID-19 pandemic in Latin America generated the need to develop low-cost, fast-manufacturing mechanical ventilators. Universidad de La Sabana and Fundacion Neumologica Colombiana designed manufactured Unisabana-HERONS (USH) ventilator. Here, we present preclinical clinical study results evaluate its effectiveness safety characteristics an animal model (Y
La criptococosis es la infección fúngica ocasionada por el complejo de especies Cryptococcus neoformans y gattii, desarrollada con mayor frecuencia en personas compromiso del sistema inmune. En las que viven virus inmunodeficiencia humana (VIH), una oportunista gran importancia, consecuencias devastadoras para los pacientes, sociedad salud, debido al incremento morbilidad, mortalidad costos genera. presente guía contiene recomendaciones diagnóstico tratamiento adultas VIH, basadas evidencia,...
Abstract Background Utilizing clinical tests, such as objective cough measurement, can assist in predicting the success of weaning process critically ill patients. Methods A multicenter observational analytical study was conducted within a prospective cohort patients recruited to participate COBRE-US. We assessed capability measurement predict spontaneous breathing trial (SBT) and extubation. Intra- inter-observer reproducibility test evaluated using intraclass correlation coefficient (ICC)...
Objective: To evaluate COVID-19 knowledge, attitudes, and practices among health care workers (HCWs) practicing in Latin American countries during the first surge of pandemic. Methods: This was a multinational cross-sectional survey study, using an online self-administered questionnaire. The final version questionnaire comprised 40 questions, organized five sections: demographic professional characteristics; knowledge; attitudes toward COVID-19; practices; institutional resources. Results:...
There is scarce information on the burden of invasive pneumococcal disease (IPD) among adults in low- and middle-income countries. This study aimed to describe clinical outcomes microbiological characteristics associated with IPD subgroups aged 18-59 years ≥60 Colombia.A retrospective chart review was conducted five institutions Bogotá from January 2011 December 2017. Analyses were carried out for overall population stratified by age group (18-59; ≥ 60 years).There 169 cases; median 58...
The successful application of ABO-incompatible (ABO-i) kidney transplantation has led to a growing interest in its lung (LTx), as it may alleviate potential organ shortages. Worldwide, LTx rates have decreased during the COVID-19 pandemic, which had significant impact on waiting list mortality. According National Institute Health's 2022 annual report, accounted for only 3.6% all transplants Colombia [1].
Introducción: el compromiso respiratorio en la enfermedad de Pompe es una sus manifestaciones más frecuentes, tiene un impacto negativo calidad vida y facilita aparición múltiples complicaciones. Se puede presentar como parte evolutiva o incluso ser síntoma inicial patología. Contenidos: presentación clínica del se caracteriza por disnea, ortopnea, cefalea tos, cambios paraclínicos incluyen hipercapnia, policitemia, elevación índice apnea/hipopnea, así disminución capacidad vital las...
ResumenLa tuberculosis es una enfermedad infecciosa de prevalencia variable a nivel mundial causada por organismos del complejo Mycobacterium con compromiso predominantemente pulmonar, pero en algunos casos puede presentar diseminación hematógena como su variante miliar.Durante la pandemia el coronavirus 2 síndrome respiratorio agudo grave (SARS-CoV-2) hubo reducción considerable detección pulmonar y miliar, lo que llevó presentación formas graves asociadas dificultad respiratoria aguda...
We present a case of 16-year-old adolescent female with blood group O+ who was diagnosed cystic fibrosis (CF). The patient had to be hospitalized due septic shock and respiratory failure, extracorporeal membrane oxygenation mechanical ventilation were applied. Faced high urgency, she promptly enlisted for lung transplant, ultimately receiving A1 deceased donor through rescue allocation. Bilateral incompatible transplantation, parental consent, successfully performed. postoperative course...