Hannah L. Kirking

ORCID: 0000-0003-2662-3110
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About
Contact & Profiles
Research Areas
  • COVID-19 epidemiological studies
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 and Mental Health
  • SARS-CoV-2 detection and testing
  • Respiratory viral infections research
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Virus-based gene therapy research
  • Viral Infections and Outbreaks Research
  • Tuberculosis Research and Epidemiology
  • Animal Virus Infections Studies
  • COVID-19 and healthcare impacts
  • Infection Control and Ventilation
  • COVID-19 Digital Contact Tracing
  • Disaster Response and Management
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Vaccine Coverage and Hesitancy
  • Long-Term Effects of COVID-19
  • Diagnosis and treatment of tuberculosis
  • Viral Infections and Vectors
  • Travel-related health issues
  • Olfactory and Sensory Function Studies
  • HIV/AIDS Research and Interventions
  • Influenza Virus Research Studies
  • Data-Driven Disease Surveillance

Centers for Disease Control and Prevention
2015-2025

National Center for Immunization and Respiratory Diseases
2020-2025

South Carolina Department of Health and Environmental Control
2024

CDC Foundation
2021-2023

Computer Emergency Response Team
2020-2023

Lake County
2020-2021

Utah Department of Health
2020-2021

The Recovery Center
2021

University of Wisconsin–Madison
2013-2021

University of Wisconsin–Oshkosh
2021

Coronavirus disease 2019 (COVID-19) is a caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China December, 2019. In January, 2020, state, local, and federal public health agencies investigated the case of COVID-19 Illinois, USA.Patients with confirmed were defined as those positive SARS-CoV-2 test. Contacts people exposure to patient on or after patient's symptom onset date. underwent active monitoring for 14 days following their last exposure. who...

10.1016/s0140-6736(20)30607-3 article EN other-oa The Lancet 2020-03-13
Anita Patel Daniel B. Jernigan Fatuma Abdirizak Glen R. Abedi Sharad Aggarwal and 95 more Denise Albina Elizabeth S. Allen Lauren M. Andersen Jade Anderson Megan Anderson Tara C. Anderson Kayla N. Anderson Ana C. Bardossy Vaughn Barry Karlyn D. Beer Michael Bell Sherri Berger Joseph Bertulfo Holly M. Biggs Jennifer Bornemann Josh Bornstein Willie Bower Joseph S. Bresee Clive Brown Alicia Budd Jennifer Buigut S. Bürke Rachel M. Burke Erin Burns Jay C. Butler Russell Cantrell Cristina V. Cardemil Jordan Cates Marty Cetron Kevin Chatham‐Stephens Kevin Chatham-Stevens Nora Chea Bryan Christensen Victoria Chu Kevin R. Clarke Angela A. Cleveland Nicole J. Cohen Max Cohen Amanda Cohn Jennifer Collins Rebecca M. Dahl W. Randolph Daley Vishal Dasari Elizabeth Davlantes Patrick Dawson Lisa Delaney Matthew Donahue Chad Dowell Jonathan Dyal William Christopher Edens Rachel B. Eidex Lauren Epstein Mary E. Evans Ryan Fagan Kevin Farris Leora R. Feldstein LeAnne M. Fox Mark Frank Brandi Freeman Alicia M. Fry James A. Fuller Romeo R. Galang Sue Gerber Runa H. Gokhale S. Goldstein Sue Gorman William J. Gregg William Greim Steven Grube Aron J. Hall Amber Haynes Sherrasa Hill Jennifer Hornsby‐Myers Jennifer C. Hunter Christopher Ionta Cheryl Isenhour Max W. Jacobs Kara Jacobs Slifka Daniel B. Jernigan Michael A. Jhung Jamie Jones-Wormley Anita Kambhampati Shifaq Kamili Pamela Kennedy Charlotte Kent Marie E. Killerby Lindsay Kim Hannah L. Kirking Lisa M. Koonin Ram Koppaka Christine Kosmos David T. Kuhar Wendi Kuhnert-Tallman Stephanie Kujawski Archana Kumar

On December 31, 2019, Chinese health officials reported a cluster of cases acute respiratory illness in persons associated with the Hunan seafood and animal market city Wuhan, Hubei Province, central China. January 7, 2020, confirmed that novel coronavirus (2019-nCoV) was this initial (1). As February 4, total 20,471 cases, including 2,788 (13.6%) severe illness,* 425 deaths (2.1%) had been by National Health Commission China (2). Cases have also 26 locations outside mainland China,...

10.15585/mmwr.mm6905e1 article EN MMWR Morbidity and Mortality Weekly Report 2020-02-05

Limited data are available about transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), among youths. During June 17-20, an overnight camp in Georgia (camp A) held orientation for 138 trainees and 120 staff members; members remained first session, scheduled during 21-27, were joined by 363 campers three senior on 21. Camp A adhered to measures Georgia's Executive Order* allowed camps operate beginning May 31, including requiring all trainees, members, provide...

10.15585/mmwr.mm6931e1 article EN MMWR Morbidity and Mortality Weekly Report 2020-07-31

In December 2019, a cluster of cases pneumonia emerged in Wuhan City central China's Hubei Province. Genetic sequencing isolates obtained from patients with identified novel coronavirus (2019-nCoV) as the etiology (1). As February 4, 2020, approximately 20,000 confirmed had been China and an additional 159 23 other countries, including 11 United States (2,3). On January 17, CDC U.S. Department Homeland Security's Customs Border Protection began health screenings at airports to identify ill...

10.15585/mmwr.mm6906e1 article EN MMWR Morbidity and Mortality Weekly Report 2020-02-07

Reports suggest that children aged ≥10 years can efficiently transmit SARS-CoV-2, the virus causes coronavirus disease 2019 (COVID-19) (1,2).However, limited data are available on SARS-CoV-2 transmission from young children, particularly in child care settings (3).To better understand contact tracing collected three COVID-19 outbreaks facilities Salt Lake County, Utah, during April 1-July 10, 2020, were retrospectively reviewed to explore attack rates and patterns.A total of 184 persons,...

10.15585/mmwr.mm6937e3 article EN MMWR Morbidity and Mortality Weekly Report 2020-09-11

Abstract Background The evidence base for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is nascent. We sought to characterize SARS-CoV-2 transmission within US households and estimate the household secondary infection rate (SIR) inform strategies reduce transmission. Methods recruited patients with laboratory-confirmed their contacts in Utah Wisconsin during 22 March 2020–25 April 2020. interviewed all obtain demographics medical histories. At initial visit, 14 days later,...

10.1093/cid/ciaa1166 article EN public-domain Clinical Infectious Diseases 2020-08-10

In 2021, a national emergency* for children's mental health was declared by several pediatric organizations, and the U.S. Surgeon General released an advisory† on among youths. These actions resulted from ongoing concerns about in United States, which exacerbated COVID-19 pandemic (1,2). During March-October 2020, all emergency department (ED) visits, proportion of health-related visits increased 24% children aged 5-11 years 31% adolescents 12-17 years, compared with 2019 (2). CDC examined...

10.15585/mmwr.mm7108e2 article EN MMWR Morbidity and Mortality Weekly Report 2022-02-18

During October-November 2021, clinicians at a children's hospital in Alabama identified five pediatric patients with severe hepatitis and adenovirus viremia upon admission. In November clinicians, the Department of Public Health, Jefferson County CDC began an investigation. This activity was reviewed by conducted consistent applicable federal law policy.

10.15585/mmwr.mm7118e1 article EN MMWR Morbidity and Mortality Weekly Report 2022-04-29

The B.1.1.529 (Omicron) variant, first detected in November 2021, was responsible for a surge U.S. infections with SARS-CoV-2, the virus that causes COVID-19, during December 2021-January 2022 (1). To investigate effectiveness of prevention strategies household settings, CDC partnered four jurisdictions to describe Omicron transmission 2021-February 2022. Persons sequence-confirmed infection and their contacts were interviewed. occurred 124 (67.8%) 183 households. Among 431 contacts, 227...

10.15585/mmwr.mm7109e1 article EN MMWR Morbidity and Mortality Weekly Report 2022-02-25

School closures affected more than 55 million students across the United States when implemented as a strategy to prevent transmission of SARS-CoV-2, virus that causes COVID-19 (1). Reopening schools requires balancing risks for SARS-CoV-2 infection and staff members against benefits in-person learning (2). During December 3, 2020-January 31, 2021, CDC investigated in 20 elementary (kindergarten through grade 6) had reopened Salt Lake County, Utah. The 7-day cumulative number new cases...

10.15585/mmwr.mm7012e3 article EN MMWR Morbidity and Mortality Weekly Report 2021-03-19

To better understand severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding and infectivity, we estimated SARS-CoV-2 RNA duration, described participant characteristics associated with the first negative rRT-PCR test (resolution), determined if replication-competent viruses was recoverable ≥10 days after symptom onset.We collected serial nasopharyngeal specimens from 109 individuals rRT-PCR-confirmed COVID-19 in Utah Wisconsin. We calculated viral resolution probability using...

10.1093/infdis/jiab107 article EN public-domain The Journal of Infectious Diseases 2021-02-18

Emergency departments (EDs) in the United States remain a frontline resource for pediatric health care emergencies during COVID-19 pandemic; however, patterns of health-seeking behavior have changed pandemic (1,2). CDC examined changes U.S. ED visit trends to assess continued impact on visits among children and adolescents aged 0-17 years (pediatric visits). Compared with 2019, declined by 51% 2020, 22% 2021, 23% January 2022. Although non-COVID-19 respiratory illnesses mostly declined,...

10.15585/mmwr.mm7108e1 article EN MMWR Morbidity and Mortality Weekly Report 2022-02-18
Stephanie Kujawski Karen K. Wong Jennifer P. Collins Lauren Epstein Marie E. Killerby and 95 more Claire M. Midgley Glen R. Abedi Naseer Ahmed Olivia Almendares Francisco N. Alvarez Kayla N. Anderson Sharon Balter Vaughn Barry Karri Bartlett Karlyn D. Beer Michael Ben‐Aderet Isaac Benowitz Holly M. Biggs Alison M. Binder Stéphanie Black Brandon Bonin Catherine Brown Hollianne Bruce Jonathan Bryant-Genevier Alicia Budd Diane Buell Rachel Bystritsky Jordan Cates E Charles Kevin Chatham‐Stephens Nora Chea Howard Chiou Demian Christiansen Victoria Chu Sara H. Cody Max Cohen Erin E. Conners Aaron T. Curns Vishal Dasari Patrick Dawson Traci DeSalvo George Diaz Matthew Donahue Suzanne Donovan Lindsey M. Duca Keith Erickson Mathew D. Esona Suzanne Evans Jeremy Falk Leora R. Feldstein Martin Fenstersheib Marc Fischer Rebecca Fisher Chelsea Foo Marielle Fricchione Oren Friedman Alicia M. Fry Romeo R. Galang Melissa Garcia S. I. Gerber Graham N. Gerrard Isaac Ghinai Prabhu Gounder Jonathan Grein Cheri Grigg Jeffrey D. Gunzenhauser Gary I. Gutkin Meredith Haddix Aron J. Hall George S. Han Jennifer L. Harcourt Kathleen Harriman Thomas Haupt Amber Haynes Michelle Holshue Cora Hoover Jennifer C. Hunter Max W. Jacobs Claire Jarashow Michael A. Jhung Kiran Joshi Talar Kamali Shifaq Kamili Lindsay Kim Moon Kim Jan King Hannah L. Kirking Amanda Kita-Yarbro Rachel Klos Miwako Kobayashi Anna Kocharian Kenneth Komatsu Ram Koppaka Jennifer E. Layden Yan Li Scott Lindquist Stephen Lindstrom Ruth Link‐Gelles Joana Y Lively Michelle Livingston

Abstract Introduction More than 93,000 cases of coronavirus disease (COVID-19) have been reported worldwide. We describe the epidemiology, clinical course, and virologic characteristics first 12 U.S. patients with COVID-19. Methods collected demographic, exposure, information from confirmed by CDC during January 20–February 5, 2020 to Respiratory, stool, serum, urine specimens were submitted for SARS-CoV-2 rRT-PCR testing, virus culture, whole genome sequencing. Results Among patients,...

10.1101/2020.03.09.20032896 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-03-12

Abstract In a household study, loss of taste and/or smell was the fourth most reported symptom (26/42 [62%]) among coronavirus disease 2019 (COVID-19) case patients and had highest positive predictive value (83% [95% confidence interval [CI], 55%–95%) contacts. Olfactory dysfunctions should be considered for COVID-19 identification testing prioritization.

10.1093/cid/ciaa799 article EN public-domain Clinical Infectious Diseases 2020-06-18

Limited data exist on severe acute respiratory syndrome coronavirus 2 in children. We described infection rates and symptom profiles among pediatric household contacts of individuals with disease 2019.We enrolled 2019 their contacts, assessed daily symptoms prospectively for 14 days, obtained specimens real-time reverse transcription polymerase chain reaction serology testing. Among (<18 years), we transmission, the risk factors infection, calculated positive negative predictive values....

10.1542/peds.2020-027268 article EN other-oa PEDIATRICS 2020-10-08

Abstract Background Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has principally been performed through the use real-time reverse-transcription polymerase chain reaction testing. Results such tests can be reported as cycle threshold (Ct) values, which may provide semi-quantitative or indirect measurements viral load. Previous reports have examined temporal trends in Ct values over course a SARS-CoV-2 infection. Methods Using testing data collected...

10.1093/cid/ciaa1469 article EN public-domain Clinical Infectious Diseases 2020-09-24

Abstract Background Respiratory tract infections are common, often seasonal, and caused by multiple pathogens. We assessed whether seasonal respiratory illness patterns changed during the COVID-19 pandemic. Methods categorized emergency department (ED) visits reported to National Syndromic Surveillance Program according chief complaints diagnosis codes, excluding with diagnosed SARS-CoV-2 infections. For each week 1 March 2020 through 26 December (“pandemic period”), we compared proportion...

10.1093/cid/ciab311 article EN public-domain Clinical Infectious Diseases 2021-04-09

There is increasing evidence that children and adolescents can efficiently transmit SARS-CoV-2, the virus causes coronavirus disease 2019 (COVID-19) (1-3). During July-August 2020, four state health departments CDC investigated a COVID-19 outbreak occurred during 3-week family gathering of five households in which an adolescent aged 13 years was index suspected primary patient; 11 subsequent cases occurred.

10.15585/mmwr.mm6940e2 article EN MMWR Morbidity and Mortality Weekly Report 2020-10-05

In-person learning benefits children and communities (1).Understanding the context in which transmission of SARS-CoV-2, virus that causes coronavirus disease 2019 , occurs schools is critical to improving safety inperson learning.During December 1, 2020-January 22, 2021, Cobb Douglas Public Health (CDPH), Georgia Department (GDPH), CDC investigated SARS-CoV-2 eight public elementary a single school district.COVID-19 cases* among educators students were either self-reported or identified by...

10.15585/mmwr.mm7008e4 article EN MMWR Morbidity and Mortality Weekly Report 2021-02-22

Increases in severe respiratory illness and acute flaccid myelitis (AFM) among children adolescents resulting from enterovirus D68 (EV-D68) infections occurred biennially the United States during 2014, 2016, 2018, primarily late summer fall. Although EV-D68 annual trends are not fully understood, levels were lower than expected 2020, potentially because of implementation COVID-19 mitigation measures (e.g., wearing face masks, enhanced hand hygiene, physical distancing) (1). In August 2022,...

10.15585/mmwr.mm7140e1 article EN MMWR Morbidity and Mortality Weekly Report 2022-09-27

Abstract Background Nirmatrelvir/ritonavir (N/R) reduces severe outcomes from coronavirus disease 2019 (COVID-19); however, rebound after treatment has been reported. We compared symptom and viral dynamics in individuals with COVID-19 who completed N/R similar untreated individuals. Methods identified symptomatic participants tested acute respiratory syndrome 2–positive were eligible a household transmission study. Index cases ambulatory settings their households contacts enrolled. collected...

10.1093/cid/ciad696 article EN public-domain Clinical Infectious Diseases 2023-11-14

Improved understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spectrum disease is essential for clinical and public health interventions. There are limited data on mild or asymptomatic infections, but recognition these individuals key as they contribute to viral transmission. We describe the symptom profiles from with SARS-CoV-2 infection.From 22 March April 2020 in Wisconsin Utah, we enrolled prospectively observed 198 household contacts exposed SARS-CoV-2....

10.1093/cid/ciaa1072 article EN public-domain Clinical Infectious Diseases 2020-07-23
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