A5013760178- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Child Nutrition and Water Access
- Hepatitis Viruses Studies and Epidemiology
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- Pneumonia and Respiratory Infections
- Poverty, Education, and Child Welfare
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Mining and Resource Management
- Vector-borne infectious diseases
- Bariatric Surgery and Outcomes
- Traffic and Road Safety
- Health, Environment, Cognitive Aging
- Synthesis and characterization of novel inorganic/organometallic compounds
- Organometallic Complex Synthesis and Catalysis
- Frailty in Older Adults
- Analytical chemistry methods development
Epidemic Intelligence Service
2022-2025
Centers for Disease Control and Prevention
2019-2025
University of California, Irvine
2024
Mott MacDonald (United Kingdom)
2023
Emory University
2017-2022
National Center for Immunization and Respiratory Diseases
2019-2022
Miami University
2022
Global Viral
2022
CDC Foundation
2022
University of Minnesota
2021
Risks for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care personnel (HCP) are unclear.
Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 early 2022, several previously children were identified with acute hepatitis human adenovirus viremia.
During October-November 2021, clinicians at a children's hospital in Alabama identified five pediatric patients with severe hepatitis and adenovirus viremia upon admission. In November clinicians, the Department of Public Health, Jefferson County CDC began an investigation. This activity was reviewed by conducted consistent applicable federal law policy.
The B.1.1.529 (Omicron) variant, first detected in November 2021, was responsible for a surge U.S. infections with SARS-CoV-2, the virus that causes COVID-19, during December 2021-January 2022 (1). To investigate effectiveness of prevention strategies household settings, CDC partnered four jurisdictions to describe Omicron transmission 2021-February 2022. Persons sequence-confirmed infection and their contacts were interviewed. occurred 124 (67.8%) 183 households. Among 431 contacts, 227...
Identifying occupational risk factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs) can improve HCW and patient safety.To quantify demographic, occupational, community SARS-CoV-2 seropositivity HCWs in a large system.A logistic regression model was fitted to data from cross-sectional survey conducted April June 2020, linking exposure disease 2019 (COVID-19) with seropositivity.A academic system the Atlanta, Georgia, metropolitan...
In November 2021, CDC was notified of a cluster previously healthy children with hepatitis unknown etiology evaluated at single U.S. hospital (1). On April 21, 2022, following an investigation this and reports similar cases in Europe (2,3), health advisory* issued requesting providers to report pediatric cases† public authorities. the United States Europe, many these patients have also received positive adenovirus test results (1,3). Typed specimens indicated type 41, which typically causes...
Abstract Background Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), associated with severe manifestations the disease. Pediatric immunization inactivated EV71 vaccine was initiated in 2016 Asia-Pacific region, including China. We analyzed time series HFMD cases attributable to EV71, coxsackievirus A16 (CA16), other enteroviruses Chengdu, transmission center China, assess early impacts immunization. Methods Reported were obtained from China’s...
On April 21, 2022, CDC issued a health advisory† encouraging U.S. clinicians to report all patients aged <10 years with hepatitis of unknown etiology public authorities, after identification similar cases in both the United States (1) and Europe.§ A high proportion initially reported had adenovirus detected whole blood specimens, thus advisory encouraged consider requesting testing, preferentially on specimens. For meeting criteria (patients under investigation [PUIs]), jurisdictional...
Households are a significant source of SARS-CoV-2 transmission, even during periods low community-level spread. Comparing household transmission rates by variant may provide relevant information about current risks and prevention strategies. This investigation aimed to estimate differences in risk comparing the Delta Omicron variants using data from contact tracing interviews conducted November 2021 through February 2022 five U.S. public health jurisdictions (City Chicago, Illinois; State...
The direct effectiveness of infant rotavirus vaccination implemented in 2006 the United States has been evaluated extensively, however, understanding population-level vaccine (VE) is still incomplete.We analyzed time series data on gastroenteritis (RVGE) and all-cause acute (AGE) hospitalization rates from MarketScan® Research Databases for July 2001-June 2016. Individuals were grouped into ages 0-4, 5-9, 10-14, 15-24, 25-44, 45-64 years. Negative binomial regression models fitted to monthly...
Abstract Background Rotavirus disease rates dramatically declined among children &lt;5 years of age since the rotavirus vaccine was introduced in 2006; population-level impacts remain to be fully elucidated. Methods Data from Healthcare Cost and Utilization Project State Inpatient Databases were used conduct a time-series analysis monthly hospital discharges across groups for acute gastroenteritis 2000 2013. Rate ratios calculated comparing prevaccine postvaccine eras. Results Following...
A correlate of protection for rotavirus gastroenteritis would facilitate rapid assessment vaccination strategies and the next generation vaccines. We aimed to quantify a threshold postvaccine serum antirotavirus immunoglobulin (IgA) as an individual-level immune against gastroenteritis.Individual-level data on 5074 infants in 9 GlaxoSmithKline Rotarix Phase 2/3 clinical trials from 16 countries were pooled. Cox proportional hazard models fit estimate ratios (HRs) describing relationship...
Background Sustainable control of soil-transmitted helminths requires a combination chemotherapy treatment and environmental interventions, including access to safe drinking water, sufficient water for hygiene, use clean sanitation facilities, handwashing (WASH). We quantified associations between home-, school-, community-level WASH characteristics hookworm infection—both prevalence eggs per gram stool (intensity)—among Togolese school children in the context community-based treatments...
Abstract Background Vaccination is the primary strategy to reduce influenza burden. Influenza vaccine effectiveness (VE) can vary annually depending on circulating strains. Methods We used a test-negative case-control study design estimate VE against laboratory-confirmed influenza-related hospitalizations among children (aged 6 months–17 years) across 5 seasons in Atlanta, Georgia, from 2012–2013 2016–2017. Influenza-positive cases were randomly matched controls based age and season 1:1...
Healthcare-associated norovirus outbreaks increase later but have a more pronounced seasonality than nonhealthcare outbreaks. had higher correlation with Google Trends activity (R2=0.68 vs 0.39). data may the potential to supplement existing surveillance due its real-time availability. Infect Control Hosp Epidemiol 2018;39:355-358.
In the 25 years since its inception, concept of social licence to operate (SLO) has become widely used within both industry and academia. Despite this, there is no agreement as what SLO required achieve it. This conceptual ambiguity results in organisations struggling understand how leaves many cynical about use. Through literature review, this paper brings together existing conceptualisations operate, presenting an explanatory model for individuals form judgements. We highlight four key...
Acute gastroenteritis remains a significant cause of morbidity and mortality in both high- low-resource settings. The development nucleic acid-based testing has demonstrated that viruses are common, yet often undetected, acute gastroenteritis.
Abstract Background Vaccines may play a role in controlling the spread of antibiotic resistance. However, it is unknown if rotavirus vaccination affects use United States (US). Methods Using data from IBM MarketScan Commercial Database, we conducted retrospective cohort US children born between 2007 and 2018 who were continuously enrolled for first 8 months life (N = 2 136 136). We followed through 5 years age compared completed full series by to had not received any doses vaccination....
Periodic resurgences of COVID-19 in the coming years can be expected, while public health interventions may able to reduce their intensity. We used a transmission model assess how use booster doses and non-pharmaceutical (NPIs) amid ongoing pathogen evolution might influence future waves. find that incidence is likely increase as NPIs relax, with second seasonally driven surge expected autumn 2022. However, greatly intensity both waves cumulative deaths by 20% between 7 January 2022 2023....