- Viral gastroenteritis research and epidemiology
- Clostridium difficile and Clostridium perfringens research
- Hepatitis C virus research
- Virus-based gene therapy research
- Animal Virus Infections Studies
- Hepatitis B Virus Studies
- Microscopic Colitis
- Rabies epidemiology and control
- Nosocomial Infections in ICU
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Tuberculosis Research and Epidemiology
- Viral Infections and Outbreaks Research
- COVID-19 epidemiological studies
- Infection Control in Healthcare
- Infection Control and Ventilation
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Influenza Virus Research Studies
- Biomedical and Engineering Education
- Nail Diseases and Treatments
- COVID-19 Clinical Research Studies
- Healthcare cost, quality, practices
- Traumatic Ocular and Foreign Body Injuries
- Cystic Fibrosis Research Advances
California Department of Public Health
2022-2024
Alameda County Public Health Department
2024
Centers for Disease Control and Prevention
2024
Epidemic Intelligence Service
2024
Florida Department of Health
2022
Duke University
2018-2020
Durham VA Health Care System
2020
Durham VA Medical Center
2016
Duke University Hospital
2016
Duke Medical Center
2016
On April 21, 2022, CDC issued a health advisory† encouraging U.S. clinicians to report all patients aged <10 years with hepatitis of unknown etiology public authorities, after identification similar cases in both the United States (1) and Europe.§ A high proportion initially reported had adenovirus detected whole blood specimens, thus advisory encouraged consider requesting testing, preferentially on specimens. For meeting criteria (patients under investigation [PUIs]), jurisdictional...
Abstract Background By fall 2023, RSV immunizations to protect older adults, pregnant people, and infants were recommended in the United States. Our aim was describe uptake of barriers immunization among community-based individuals during first season availability.Table 1:Targeted populations, ACIP recommendations, participant eligibility criteria for this analysis, April 20241. Due limitations how data collected parent study, used analysis may differ from exact criteria.2. Nirsevimab, a...
Abstract Background The updated 2023-2024 Coronavirus Disease 2019 (COVID-19) vaccine became available on September 11, 2023 for persons ≥ 6 months old. Understanding the targeted populations’ knowledge, attitudes, and practices regarding this latest may identify areas to improve future uptake.Table 1:Participants Characteristics Stratified by Age Receipt of COVID-19 Vaccine Methods Persons enrolled in a household transmission investigation respiratory viruses Tennessee, New York, Washington...
The California Department of Public Health (CDPH) reviewed 109 cases healthcare personnel (HCP) with laboratory-confirmed mpox to understand transmission risk in settings. Overall, 90% HCP had nonoccupational exposure factors. One occupationally acquired case was associated sharps injury while unroofing a patient's lesion for diagnostic testing.
Abstract Background Improved epidemiologic and treatment data for active tuberculosis (TB) with chronic hepatitis B virus (cHBV) infection might inform encourage screening vaccination programs focused on persons at risk of having both conditions. Methods We matched the California Department Public Health TB registry during 2016–2020 to cHBV using probabilistic matching algorithms. used chi-square analysis compare characteristics those only. compared outcomes between these groups modified...
Epidemiologic data regarding persons with active tuberculosis (TB) and chronic hepatitis B virus (cHBV) infection are limited because of lack routine surveillance cHBV in TB. Potential underdiagnosis California among those TB is concerning. We matched registries to identify infections diagnosed during 2016-2020 described their demographic characteristics. calculated expected cases for each characteristic using published prevalence estimates the locations birth Estimates were from general or...
Adults aged ≥65 years experience the highest risk for COVID-19-related hospitalization and death, with increasing age; outpatient antiviral treatment reduces these severe outcomes. Despite proven benefit of COVID-19 treatment, information on differences in use among older adults by age group is limited. Nonhospitalized patients during April 2022-September 2023 were identified from National Patient-Centered Clinical Research Network. Differences 65-74, 75-89, ≥90 assessed. Multivariable...
ABSTRACT As of August 2022, cases acute severe hepatitis unknown etiology in children have been reported from 35 countries, including the United States. Here we used PCR testing, viral enrichment based sequencing, and agnostic metagenomic sequencing to analyze 27 samples, nasopharyngeal swab, stool, plasma, and/or whole blood, 16 such 6 states (Alabama, California, Florida, Illinois, North Carolina, South Dakota) presenting October 1, 2021 May 22, parallel with blood samples 45 controls....
Rabies is an acute encephalitis that nearly always fatal. It caused by infection with viruses of the genus Lyssavirus, most common which lyssavirus. The Council State and Territorial Epidemiologists (CSTE) defines a confirmed human rabies case as illness compatible meets at least one five different laboratory criteria.* Four these criteria do not depend on patient's vaccination status; however, remaining criterion, "identification Lyssavirus-specific antibody (i.e. indirect fluorescent...
Abstract OBJECTIVE: Clostridium difficile –associated disease (CDAD) is common and has a 6.1% mortality. Governmental agencies have recommended surveillance, but reporting increases health care costs. We sought to identify reliable method of CDAD that will not significantly increase METHODS: Patients were identified via database query for International Statistical Classification Diseases Related Health Problems, 9th Edition (ICD‐9) codes C. toxin positivity. All patients underwent chart...
Mucormycosis is a rare fungal infection, but can cause substantial morbidity and mortality in both immunocompromised immunocompetent patients. Apophysomyces mucormycetes species ubiquitous nature, particularly soil, decaying wood other organic matter. known to cutaneous infections, after penetrating trauma. Septic arthritis clinical manifestation.We describe case of trapeziformis causing septic the knee patient with multiple myeloma. He was treated times for bacterial minimal improvement....
Background: Burkholderia multivorans are gram-negative bacteria typically found in water and soil. B. outbreaks among patients without cystic fibrosis have been associated with exposure to contaminated medical devices or nonsterile aqueous products. Acquisition can also occur from environmental reservoirs like sinks other hospital sources. We describe an outbreak of hospitalized at 2 hospitals within the same healthcare system California (hospitals A B) between August 2021 July 2022....
Objectives: Few reports have been published about the transmission of mpox in healthcare settings. During 2022 multinational outbreak, California Department Public Health (CDPH) conducted a systematic review personnel (HCP) with mpox, including their community and occupational exposures, to understand risk We also sought inform return-to-work protocols by describing frequency HCP working while symptomatic for identifying occurrences secondary from infected patients. Methods: analyzed...