- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Alcohol Consumption and Health Effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Liver Diseases and Immunity
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Tuberculosis Research and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Diet, Metabolism, and Disease
- Renal Transplantation Outcomes and Treatments
- Gallbladder and Bile Duct Disorders
- Drug-Induced Hepatotoxicity and Protection
- Inflammatory Bowel Disease
- Multiple and Secondary Primary Cancers
- Microscopic Colitis
- Healthcare Policy and Management
- Heme Oxygenase-1 and Carbon Monoxide
- Obesity, Physical Activity, Diet
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Folate and B Vitamins Research
- Pancreatitis Pathology and Treatment
VA Palo Alto Health Care System
2013-2025
Stanford University
2012-2025
Veterans Health Administration
2025
Stanford Medicine
2000-2025
Stony Brook University
2023-2024
Palo Alto University
2021-2024
Retina Associates
2015-2024
SUNY Downstate Health Sciences University
1980-2023
State University of New York
1980-2023
Chinese University of Hong Kong
2023
The metabolic syndrome contributes to cardiovascular morbidity and mortality. 1-4Data from the National Health Nutrition Examination Survey (NHANES) 1999-2006 reported a prevalence of 34%. 5 Understanding updated trends may be important given potential effect its associated health complications on aging US population.We investigated in through 2012.a Trend comparisons year ranges listed 2011-2012.
This study uses US national survey data to characterize trends in the prevalence of metabolic syndrome among adults between 2011 and 2016.
Nonalcoholic steatohepatitis (NASH) is currently the third leading indication for liver transplantation (LT) in U.S. and predicted to become LT near future. The trends NASH-related hepatocellular carcinoma (HCC) among recipients remain undefined. We performed a retrospective cohort study evaluate etiology of HCC adult from 2002 2012, using national data United Network Organ Sharing registry. From 2002-2012, there were 61,868 adults who underwent U.S., including 10,061 patients with HCC....
Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology practices, it can have multiple presentations, ranging from asymptomatic elevations biochemistries to hepatocellular or cholestatic jaundice, failure, chronic hepatitis. Antimicrobials, herbal dietary supplements, anticancer therapeutics (e.g., tyrosine kinase inhibitors immune-checkpoint inhibitors) are the most classes of agents cause DILI Western world. a diagnosis exclusion, thus, careful...
One factor associated with the rapidly increasing clinical and economic burden of chronic liver disease (CLD) is inpatient health care utilization.To understand trends in hospitalization CLD US.This cross-sectional study hospitalized adults US used data from National Inpatient Sample 2012 to 2016 on adult CLD-related hospitalizations. Data were analyzed June October 2019.Hospitalizations identified using a comprehensive review CLD-specific International Classification Diseases, Ninth...
Using the United Network for
Esophageal symptoms are common and may indicate the presence of gastroesophageal reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or functional disorders. physiologic tests often performed when initial endoscopic evaluation is unrevealing, especially persist despite empiric management. Commonly used esophageal include manometry, ambulatory monitoring, barium esophagram. Functional lumen imaging probe (FLIP) has recently been approved for pressure...
Summary Background Risk factors and timing associated with disease progression mortality in nonalcoholic fatty liver (NAFLD) are poorly understood. Aims To evaluate the impact of severity, demographics comorbidities on risk time to a large, real‐world cohort diagnosed NAFLD patients. Methods Claims data from 20% Medicare representative sample between 2007 2015 were analysed retrospectively. Adults categorised into severity groups: NAFLD/nonalcoholic steatohepatitis (NASH) alone, compensated...
This national survey study uses National Health and Nutrition Examination Survey (NHANES) data to estimate the prevalence of alcoholic fatty liver disease (AFLD) overall with stage 2 or greater 3 fibrosis among US adults from 2001 2016.
Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospitalization in the United States and associated with significant utilization of hospital resources, as well considerable morbidity mortality. These revised guidelines implement Grading Recommendations, Assessment, Development, Evaluation methodology to propose recommendations use risk stratification tools, thresholds red blood cell transfusion, reversal agents patients on anticoagulants, diagnostic testing including...
Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe impairment and rapid clinical deterioration patients without preexisting disease. Due to the rarity of this condition, published studies are limited by use retrospective or prospective cohorts lack randomized controlled trials. Current guidelines represent suggested approach identification, treatment, management ALF official practice recommendations American College Gastroenterology. The...
ABSTRACT Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic and frequent indication for transplantation worldwide. With harmful alcohol use as primary risk factor, increasing over past decade has resulted in rapid growth ALD-related healthcare burden. The spectrum ALD ranges from early asymptomatic injury to with decompensation portal hypertension. Compared those other etiologies disease, patients progress faster more often present at an stage. A unique...
Summary Background and Aims The objective of the study was to analyse prevalence, incidence, death alcohol‐associated liver disease (ALD) among adolescents young adults globally, continentally, nationally, focusing on trends over time. Methods analysed data from Global Burden Disease (GBD) between 2000 2019. It examined ALD's in aged 15–29, segmented by region, nation, sociodemographic index. analysis utilised Joinpoint regression modelling calculate annual per cent change (APC) rate these...
This cross-over study compared the pharmacokinetic parameters obtained from cyclosporine (CsA) concentration-time profiles after administration of corn oil-based soft gel cap (CsA-GC) with those microemulsion (CsA-ME) cap. Neither fasting state nor coadministration a low- or high-fat breakfast affected pharmacokinetics CsA presented in either formulation. Comparisons three sets parameters—namely, low-fat diets—demonstrated CsA-ME formulation to display greater intraindividual reproducibility...
This cross-over study compared the pharmacokinetic parameters obtained from cyclosporine (CsA) concentration-time profiles after administration of corn oil-based soft gel cap (CsA-GC) with those microemulsion (CsA-ME) cap. Neither fasting state nor coadministration a low- or high-fat breakfast affected pharmacokinetics CsA presented in either formulation. Comparisons three sets parameters—namely, low-fat diets—demonstrated CsA-ME formulation to display greater intraindividual reproducibility...