David Wan

ORCID: 0000-0001-9361-8245
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About
Contact & Profiles
Research Areas
  • Gastrointestinal disorders and treatments
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal and GI Pathology
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Abdominal vascular conditions and treatments
  • Gastric Cancer Management and Outcomes
  • Eosinophilic Esophagitis
  • Pancreatitis Pathology and Treatment
  • Diverticular Disease and Complications
  • Biliary and Gastrointestinal Fistulas
  • Metastasis and carcinoma case studies
  • Topic Modeling
  • Natural Language Processing Techniques
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Microscopic Colitis
  • Lymphoma Diagnosis and Treatment
  • Advanced Text Analysis Techniques
  • Potassium and Related Disorders
  • Gallbladder and Bile Duct Disorders
  • Cancer Diagnosis and Treatment
  • Appendicitis Diagnosis and Management
  • Inflammatory Bowel Disease
  • Eosinophilic Disorders and Syndromes
  • IgG4-Related and Inflammatory Diseases

Presbyterian Hospital
2016-2025

New York Hospital Queens
2015-2025

NewYork–Presbyterian Hospital
2015-2025

Cornell University
2015-2024

Weill Cornell Medicine
2017-2024

University of North Carolina Health Care
2023

University of North Carolina at Chapel Hill
2022-2023

NewYork–Presbyterian Brooklyn Methodist Hospital
2023

Singapore University of Social Sciences
2021

New York University
2006-2011

Recent reports suggest that prevalence of gastrointestinal (GI) and hepatic manifestations in COVID-19 are higher than initially reported, particularly Western populations. New York City has arguably been the epicenter pandemic United States, creating a unique opportunity to further understanding this disease. Our objectives were investigate GI patients with COVID-19, explore their effect on clinical outcomes these patients. This is retrospective review consecutive adult (age ≥18) positive...

10.1053/j.gastro.2020.05.010 article EN other-oa Gastroenterology 2020-05-08

Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospitalization in the United States and associated with significant utilization of hospital resources, as well considerable morbidity mortality. These revised guidelines implement Grading Recommendations, Assessment, Development, Evaluation methodology to propose recommendations use risk stratification tools, thresholds red blood cell transfusion, reversal agents patients on anticoagulants, diagnostic testing including...

10.14309/ajg.0000000000002130 article EN The American Journal of Gastroenterology 2022-09-21

Although current literature has addressed gastrointestinal presentations including nausea, vomiting, diarrhea, abnormal liver chemistries, and hyperlipasemia as possible coronavirus disease 2019 (COVID-19) manifestations, the risk type of bleeding (GIB) in this population is not well characterized.This a matched case-control (1:2) study with 41 cases GIB (31 upper 10 lower) patients COVID-19 82 controls without GIB. The primary objective was to characterize etiologies, our secondary aim...

10.14309/ajg.0000000000000805 article EN The American Journal of Gastroenterology 2020-08-13

We present FactPEGASUS, an abstractive summarization model that addresses the problem of factuality during pre-training and fine-tuning: (1) augment sentence selection strategy PEGASUS's (Zhang et al., 2019) objective to create pseudo-summaries are both important factual; (2) introduce three complementary components for fine-tuning. The corrector removes hallucinations in reference summary, contrastor uses contrastive learning better differentiate nonfactual summaries from factual ones,...

10.18653/v1/2022.naacl-main.74 article EN cc-by Proceedings of the 2022 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies 2022-01-01

Despite significant progress in understanding and improving faithfulness abstractive summarization, the question of how decoding strategies affect is less studied. We present a systematic study effect generation techniques such as beam search nucleus sampling on summarization. find consistent trend where with large sizes produces most faithful summaries while generates least ones. propose two faithfulness-aware methods to further improve over current techniques: (1) ranking candidates...

10.18653/v1/2023.eacl-main.210 article EN cc-by 2023-01-01

CASE REPORT A 65-year-old man with no significant past medical history was admitted to an outside hospital 1.5 months of crampy, lower abdominal pain associated rectal urgency and tenesmus. Initial computed tomography showed thickening his rectosigmoid mid distal descending colon; follow-up colonoscopy revealed inflammation the affected areas focal lamina propria vascular congestion sloughing epithelium in colon. course antibiotics followed by a oral steroids did not improve symptoms. He...

10.14309/crj.2016.57 article EN cc-by-nc-nd ACG Case Reports Journal 2016-01-01

The problems of unfaithful summaries have been widely discussed under the context abstractive summarization. Though extractive summarization is less prone to common unfaithfulness issues summaries, does that mean equal faithful? Turns out answer no. In this work, we define a typology with five types broad (including and beyond not-entailment) can appear in including incorrect coreference, incomplete discourse, as well other misleading information. We ask humans label these 1600 English...

10.18653/v1/2023.acl-long.120 article EN cc-by 2023-01-01

The real-world efficacy of computer-aided detection (CADe) systems, such as GI Genius (Medtronic), is unclear. We examined the colonoscopy metrics using CADe alone and with a mucosal exposure device (EndoCuff; Olympus) in setting. retrospectively reviewed screening surveillance colonoscopies before, during, after use large tertiary care center. Outcomes included adenomas per (APC), sessile serrated lesions colonoscopy, adenoma rate (ADR), lesion (SSLDR), advanced ADR, total polyp rate, true...

10.5946/ce.2024.271 article EN cc-by-nc Clinical Endoscopy 2025-04-22

OBJECTIVES Although sexual dysfunction has been reported in patients with hepatitis C virus (HCV) infection, little is known about this association. The aims of study were to determine the prevalence among men chronic HCV infection and evaluate impact on health-related quality life (HRQOL). METHODS We prospectively enrolled 112 positive 239 negative controls, all completed validated questionnaires assess function (Brief Male Sexual Function Inventory [BMSFI]), depression (Beck Depression...

10.1111/j.1572-0241.2006.00544.x article EN The American Journal of Gastroenterology 2006-04-29

Routine screening for hepatocellular carcinoma (HCC) is recommended in chronic hepatitis B (HBV) patients with cirrhosis and select non-cirrhotic HBV populations including Asian males ages 40 older females 50 older. However, many younger develop HCC there have been few studies examining this group. Additionally, of the immigrant population United States limited. The objective study was to determine associated risk factors development early-onset (males under 50, respectively) late-onset...

10.1038/ajg.2011.302 article EN The American Journal of Gastroenterology 2011-09-13

Premature atherosclerotic cardiovascular disease (ASCVD) is a common and devastating complication of systemic lupus erythematosus (SLE). It likely that immunologic derangements contribute to premature ASCVD in these patients, possibly by disrupting homeostatic mechanisms orchestrate cholesterol balance monocytes/macrophages the artery wall. CD36, macrophage scavenger receptor responsible for recognition internalization oxidized lipids, major participant foam cell formation. We hypothesized...

10.3181/0806-bc-194 article EN Experimental Biology and Medicine 2009-01-15

ABSTRACT Rituximab (RTX), a widely used monoclonal antibody for hematologic malignancies and rheumatologic disorders, is known infusion-related reactions. However, its potential to induce colitis often overlooked. We present an 85-year-old woman with chronic lymphocytic leukemia experiencing severe adverse effects during her fourth RTX infusion, including abdominal pain, hypotension, bright red blood per rectum. Computed tomography of the abdomen pelvis contrast revealed pancolonic mural...

10.14309/crj.0000000000001274 article EN cc-by-nc-nd ACG Case Reports Journal 2024-02-01

Autoimmune hepatitis (AIH) is a progressive, chronic that has rarely been reported in HIV-infected individuals. Among patients who are candidates for C virus (HCV) treatment, screening AIH should be considered, because interferon the potential to cause fulminant hepatic failure setting of immune-mediated injury. During 4-year period, we identified four were referred evaluation persistently elevated aminotransferases, two whom also infected with HCV. Serologic testing and histologic...

10.1089/apc.2008.0149 article EN AIDS Patient Care and STDs 2009-04-30

The quantum annealing devices, which encode the solution to a computational problem in ground state of Hamiltonian, are implemented D-Wave systems with more than 2,000 qubits. However, can solve only classical combinatorial optimization such as an Ising model, or equivalently, quadratic unconstrained binary (QUBO) problem. In this paper, we formulate QUBO model elliptic problems Dirichlet and Neumann boundary conditions using finite element method. formulation, develop objective function...

10.1117/12.2649076 article EN 2023-03-08

10.14309/01.ajg.0001048468.56835.fe article EN The American Journal of Gastroenterology 2024-10-01

1Division of Gastroenterology and Hepatology, Weill Cornell Medical Center, New York, USA; 2Section Gastroenterology, Nutrition, University Chicago Medicine, Chicago, Illinois, USA. Correspondence: Neil Sengupta, MD. Email: [email protected].

10.14309/ajg.0000000000002505 article EN The American Journal of Gastroenterology 2023-09-19

Although drug-induced liver injury is common, physician awareness of specific drug reactions often limited. Celecoxib-induced has not been widely reported. We describe the case a 28 year-old woman who presented to emergency department with cholestatic following 13 days celecoxib use. searched literature and reviewed existing reports celecoxib-induced highlight similarities offer discussion associated pathology.

10.5430/crcp.v1n2p90 article EN Case Reports in Clinical Pathology 2014-05-13
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