A5019819409- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Gastric Cancer Management and Outcomes
- Liver physiology and pathology
- Genetic and Kidney Cyst Diseases
- Helicobacter pylori-related gastroenterology studies
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Liver Diseases and Immunity
- Alcohol Consumption and Health Effects
- Metastasis and carcinoma case studies
- Diagnosis and treatment of tuberculosis
- Inflammatory Bowel Disease
- COVID-19 Clinical Research Studies
- Pregnancy and preeclampsia studies
- Systemic Sclerosis and Related Diseases
- Folate and B Vitamins Research
- Diabetes Treatment and Management
- Lipid metabolism and disorders
- Bariatric Surgery and Outcomes
- Drug Transport and Resistance Mechanisms
- Diet and metabolism studies
- Genetic factors in colorectal cancer
- Nutrition and Health in Aging
Cornell University
2017-2024
Presbyterian Hospital
2017-2024
Weill Cornell Medicine
2019-2024
New York Hospital Queens
2019-2023
NewYork–Presbyterian Hospital
2019-2023
University of North Carolina at Chapel Hill
2013
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a common cause of chronic liver disease globally, with prevalence rapidly increasing in parallel rising rates obesity and metabolic syndrome. MASLD defined by the presence excess fat liver, which may induce inflammatory changes subsequent fibrosis high-risk patients. Though occurs frequently, there still no approved pharmacological treatment, mainstay therapy remains lifestyle modification via dietary changes, enhancement...
Although bioinformatic analysis of the increasing numbers diverse genome sequences and amount functional data has provided insight into evolution signaling networks, bioinformatics approaches have limited application for understanding highly divergent protein families. We used biochemical analyses to determine in vitro properties selected components heterotrimeric guanine nucleotide-binding (G protein) network investigate evolution. In animals, G proteins are activated by cell-surface...
Background and Aims: Covert HE (CHE) is a common early stage of associated with poor outcomes. Available neuropsychiatric diagnostic testing underutilized has significant clinical limitations. Sleep deterioration consistently CHE HE; however, objective data sparse it not been studied longitudinally. We longitudinally study describe an association sleep metrics as detected by commercial wearable technology. Methods: monitored for 6 months using fitness tracker in 25 participants cirrhosis,...
Background: Acute variceal hemorrhage is a major decompensating event in patients with cirrhosis and associated high 6-week mortality risk. Many prognostic models based on clinical laboratory parameters have been developed to risk stratify index bleeding presentation, including those the Model for End-Stage Liver Disease (MELD) Child-Turcotte-Pugh (CTP). However, consensus model performance remains unclear. Methods: Using large US multicenter cohort of hospitalized who presented acute...
A 35-year-old man with sickle-cell trait and diabetes who had undergone renal transplantation presented weeks of episodic severe cramping, abdominal pain, diarrhea, maroon stool, anorexia despite using empiric antibiotics for gastroenteritis. At presentation, his laboratory results noted a mild leukocytosis hemoglobin 6.4 g/dL. Real-time polymerase chain reaction nasopharyngeal sample gave positive result SARS-CoV-2 the lack respiratory symptoms or fever. CT scan demonstrated diffusely...
Gastrointestinal symptoms are prevalent in patients with cirrhosis. Cirrhotic have a known predilection to delayed gastric emptying compared those without However, the contributing factors not been fully elucidated. Retained food on esophagogastroduodenoscopy (EGD) has used as surrogate marker for reasonably high specificity. Therefore, we hypothesize that frequency of retained contents at EGD will be higher cirrhotic population control liver disease. Additionally, increased associated...
Research suggests optimizing sleep, exercise and work-life balance may improve resident physician burnout. Wearable biosensors allow residents to detect correct poor sleep habits before burnout develops. Our objectives were evaluate the feasibility of a wearable biosensor characterize exercise/sleep in neurology examine its relationship self-reported, validated survey measures. We also assessed device's impact on well-being barriers use.This prospective cohort study evaluated WHOOP Strap 2.0...
Primarily a disease of the colon, extra-intestinal manifestations Ulcerative Colitis (UC) commonly include arthritis, uveitis, and hepatobiliary disease. Cardiac involvement is rare, with an incidence ratio 2.6 above baseline population,1 but fatalities have been reported. Confounding UC drug toxicities make diagnosis all more difficult, important, to identify clinically. A 35 year-old man occasional cocaine use presented myalgias substernal, tearing chest pain pleuritis that had progressed...
INTRODUCTION: Strongyloides Hyperinfection Syndrome (SHS) is a severe complication of strongyloidiasis that associated with respiratory, gastrointestinal, and characteristic dermatologic features, can lead to significant mortality. We present the case an immunosuppressed patient who developed SHS following corticosteroid therapy. CASE DESCRIPTION/METHODS: A 67-year-old male leukemia on ibrutinib obinutuzumab presented persistent non-productive cough dyspnea unresponsive methylprednisolone....
INTRODUCTION: Upper gastrointestinal bleeding (UGIB) causes significant morbidity and mortality in the United States. Indications for emergent EGD include acute bleeding. Bleeding of esophageal tract is a known complication transesophageal echocardiography (TEE.)1 Risk factors due to TEE previous ulcerative processes, anti-coagulant use coagulopathy.1,2 CASE DESCRIPTION/METHODS: A 65-year-old woman with history aortic mitral valve stenoses s/p mechanical valves on warfarin, severe pHTN ESRD...