A5076880309- Pharmaceutical Economics and Policy
- Global Maternal and Child Health
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical industry and healthcare
- Travel-related health issues
- Parasites and Host Interactions
- Malaria Research and Control
- Mosquito-borne diseases and control
- Biosimilars and Bioanalytical Methods
- Hepatitis C virus research
- Antifungal resistance and susceptibility
- Hepatitis B Virus Studies
- Vaccine Coverage and Hesitancy
- Pharmaceutical studies and practices
- Migration, Health and Trauma
- Long-Term Effects of COVID-19
- Research on Leishmaniasis Studies
- Global Health and Surgery
- Infectious Diseases and Tuberculosis
- Parasitic Infections and Diagnostics
- Viral Infections and Vectors
- Peripheral Neuropathies and Disorders
- Cultural Competency in Health Care
- SARS-CoV-2 and COVID-19 Research
- Fungal Infections and Studies
University of Minnesota
2014-2025
Minneapolis VA Health Care System
2023-2025
HealthPartners
2018-2023
Center for Global Health
2021
Minnesota Department of Health
2017-2020
University of Liège
2017
Care Resource
2017
Regions Hospital
2014-2016
Virginia Commonwealth University Medical Center
2010-2011
Postauthorization monitoring of vaccines in a large population may detect rare adverse events not identified clinical trials such as Guillain-Barré syndrome (GBS), which has background rate 1 to 2 per 100 000 person-years.To describe cases and incidence GBS following COVID-19 vaccination assess the risk after for Ad.26.COV2.S (Janssen) mRNA vaccines.This cohort study used surveillance data from Vaccine Safety Datalink at 8 participating integrated health care systems United States. There...
James M. Sanders, PhD, PharmD; Marguerite L. Monogue, Tomasz Z. Jodlowski, B. Cutrell, MD
<h3>Importance</h3> After SARS-CoV-2 infection, many patients present with persistent symptoms for at least 6 months, collectively termed<i>post-COVID conditions</i>(PCC). However, the impact of PCC on health care utilization has not been well described. <h3>Objectives</h3> To estimate COVID-19–associated excess following acute infection and describe select PCCs among who had positive test results (including reverse transcription–polymerase chain reaction antigen tests) compared control...
Some older generic drugs have become very expensive, owing to factors including drug shortages, supply disruptions, and consolidations in the generic-drug industry. But generics manufacturers that legally obtain a market monopoly can also unilaterally raise prices.
Cutaneous leishmaniasis (CL) may be emerging among international travellers and migrants. Limited data exist on mucocutaneous (MCL) in travellers. We describe the epidemiology of travel-associated CL MCL immigrants over a 20-year period through descriptive analysis GeoSentinel data.Demographic travel-related returned diagnosed with or at Surveillance Network site between 1 September 1997 31 August 2017 were analysed.A total 955 migrants travel-acquired (n = 916) during study period, whom 10%...
Importance Beyond traditional race and ethnicity demographic characteristics, additional discrete data variables are needed for informed health interventions in the US. Objective To examine whether COVID-19 vaccine uptake patterns associated disease outcomes differ among language preference groups. Design, Setting, Participants A cohort study of 851 410 individuals aged 18 years or older a large multispecialty system Minnesota western Wisconsin was conducted between December 15, 2020, March...
The authors declared no conflict of interest.
Abstract In this cross-sectional analysis, we analyzed 117 US clinics in Lyme endemic states that provide nontraditional care for disease. We found unproven therapies are routinely offered, and some raise safety concerns. The cost of can be high, which may lead to significant out-of-pocket expenditures patients.
Cross-cultural care is recognized by the ACGME as an important aspect of US residency training. Resident physicians' preparedness to deliver cross-cultural has been well studied, while provide specifically immigrant and refugee populations not been.We administered a survey in October 2013 199 residents Internal Medicine, Pediatrics, Medicine/Pediatrics at University Minnesota, assessing perceived knowledge, attitudes, experience with patients.Eighty-three enrolled Pediatrics programs...
Prices have been dramatically increasing for many older, off-patent drugs, some of which are considered "essential" by the World Health Organization. Some price hikes made potentially life-saving therapies unavailable to disadvantaged patients in United States.
In recent years, the price of many older generic drugs, including numerous antibiotics, has increased substantially. We sought to analyze changes and extent competition within a cohort commonly prescribed off-patent oral antibiotics. extracted antibiotics recommended for common outpatient conditions in Infectious Diseases Society America Practice Guidelines. determined all US Food Drug Administration–approved manufacturers each formulation strength 2013 2016 yearly national average drug...
Abstract The diagnosis of blastomycosis is often delayed. We identified 28 cases pulmonary in a retrospective chart review. Most patients received multiple antibiotic courses before being diagnosed, and the sputum KOH smear was rarely used. Diagnostic delay can be decreased with higher suspicion for early use smear.
Drugs for neglected tropical diseases (NTD) are being excessively priced in the United States. Benznidazole, first-line drug Chagas disease, may become approved by Food and Drug Administration (FDA) manufactured a private company US, thus placing it at risk of similar pricing. disease is an NTD caused Trypanosoma cruzi; endemic to Latin America, infecting 8 million individuals. Human migration has changed epidemiology causing nonendemic countries face increased challenges diagnosing managing...
Eighteen cases of chikungunya virus infection in travellers returning from Myanmar were reported to the GeoSentinel Surveillance Network, its subnetwork EuroTravNet and TropNet 2019, reflecting an ongoing local outbreak. This report reinforces importance as sentinels emerging arboviral outbreaks highlights vigilance for imported cases, due potential dissemination into areas with competent vectors conducive environmental conditions.
Introduction: Understanding of COVID-19 related disparities in the United States is largely informed by traditional race/ethnicity categories that mask important social group differences. This analysis utilizes granular information on patients' country birth and preferred language from a large health system to provide more nuanced insights disparities.Methods: Data patients seeking care Midwestern between January 1, 2019, July 31, 2021, events occurring March 18, 2020 2021 were used describe...
Background Despite achievements in the reduction of malaria globally, imported cases to United States by returning international travelers continue increase. Immigrants from sub-Saharan Africa (SSA) who then travel back their homelands visit friends and relatives (VFRs) experience a disproportionate burden illness. Various studies have explored barriers prevention among VFRs non-VFRs–travelers same destinations with other purpose for travel–but few employed robust epidemiologic study designs...
Nontuberculous mycobacteria (NTM) are a rare cause of prosthetic joint infections (PJI). However, the prevalence NTM may be increasing with rise newer immunosuppressive medications such as biologics. In this case report, we describe complication therapies and highlight complexity diagnosing treating PJI due to NTM. The patient is 79-year-old Caucasian male history severe destructive rheumatoid arthritis on several agents right hip osteoarthritis s/p total arthroplasty 15 years previously...
Ozena, or atrophic rhinitis, is a chronic nasal process seen in Africa, India, and the Middle East. It marked by triad of fetid discharge, crusting, atrophy, often associated with Klebsiella infection. We present cases ozena three unrelated patients, including two east African children one Saudi adult. All patients grew species culture required prolonged treatment multiple methodologies, antibiotics, saline rinses, surgical debridement. They differed greatly time from presentation to...
<h3>Importance</h3> Some sole-source, off-patent drugs in the United States have undergone substantial price hikes recent years. Despite increased attention by lawmakers, there are limited data to guide policy. <h3>Objectives</h3> To describe key attributes of off-patent, off-exclusivity drugs; characterize prevalence increases; and identify associated with increases. <h3>Design, Setting, Participants</h3> In this cross-sectional study, 300 drug products met inclusion criteria were selected...
As states and health systems prepare to deliver severe acute respiratory syndrome coronavirus 2 vaccines the American public, a confluence of factors has potential interfere with these efforts: misinformation about disease 2019, vaccine hesitancy, erosion public's trust in regulatory process due recent ongoing events. Broad action is needed address issues, including improved consistent communication by Food Drug Administration, restoration Centers for Disease Control as an independent...
Outpatient costs SOC prescription drug costsPatients receiving drugsNumbers of patients with hookworm, pinworm, and Clostridioides difficile who were treated (and not treated) drugs are as follows.For the numbers 267 (360) in 2010 to 2011, 206 (413) 2012 2013, 156 (385) 2014 2015, 219 (572) 2016 2018.For 4283 (1007) 2010, 4915 (1286) 4207 (2121) 2012, 1917 (2810) 1551 (3300) 2014, 1322 (2849) 1218 (3076) 2016, 1234 (2940) 2017, 807 (2064) C difficile, 2383 (1070) 3393 (1320) 4057 (1461) 3663...
Strongyloides stercoralis has the potential to cause accelerated autoinfection in immunocompromised hosts. Screening tests for strongyloidiasis may be falsely negative setting of immunosuppression. We report a case hyperinfection syndrome patient with human T-lymphotropic virus type 1-associated T-cell leukemia early after hematopoietic stem cell transplant. The diagnosis was made by stool ova and parasite examination, despite screening enzyme-linked immunosorbent assay. Because anticipated...