A5023291452- Neural dynamics and brain function
- Neural Networks and Applications
- Evolutionary Algorithms and Applications
- Anesthesia and Sedative Agents
- Advanced Memory and Neural Computing
- Neural Networks and Reservoir Computing
- Hearing Impairment and Communication
- Functional Brain Connectivity Studies
- Childhood Cancer Survivors' Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Simulation and Modeling Applications
- Disability Education and Employment
- Cognitive and developmental aspects of mathematical skills
- EEG and Brain-Computer Interfaces
- Acute Lymphoblastic Leukemia research
- Hemodynamic Monitoring and Therapy
- Inclusion and Disability in Education and Sport
- Family and Patient Care in Intensive Care Units
- Cancer Immunotherapy and Biomarkers
- Palliative Care and End-of-Life Issues
- Image Processing and 3D Reconstruction
- Pharmaceutical studies and practices
- Hearing, Cochlea, Tinnitus, Genetics
- Digital Accessibility for Disabilities
- Acupuncture Treatment Research Studies
ETH Zurich
2019-2025
University of Chicago
2020-2021
Board of the Swiss Federal Institutes of Technology
2021
University of Chicago Medical Center
2021
Sidney Kimmel Comprehensive Cancer Center
2019-2020
Johns Hopkins Medicine
2016-2019
Johns Hopkins University
2016-2019
Bloomberg (United States)
2019
Center for Neurosciences
2018
École Polytechnique Fédérale de Lausanne
2018
Immune checkpoint inhibitors (ICIs) cause immune-related adverse events (irAEs). The proportion of patients who are hospitalized for irAEs and their spectrum, management, outcomes not well described.We report the in an academic center were treated with ICIs from May to December 2017. Patient characteristics, toxicities, confirmed irAE admissions reported. Associations between patient features hospitalizations examined.Twenty-three percent (n = 100) 443 admitted oncology over 6 months had...
Human decisions are based on finite information, which makes them inherently imprecise. But what determines the degree of such imprecision? Here, we develop an efficient coding framework for higher-level cognitive processes in information is represented by a number discrete samples. We characterize sampling process that maximizes perceptual accuracy or fitness under often-adopted assumption full adaptation to environmental distribution possible, and show how optimal differs when detailed...
The ability to rapidly estimate non-symbolic numerical quantities is a well-conserved sense across species with clear evolutionary advantages. However, despite its importance, this surprisingly imprecise and biased, formal explanation for seemingly irrational behavior remains unclear. We develop unified normative theory of numerosity estimation that parsimoniously incorporates in single framework information processing constraints alongside (i) Brownian diffusion noise capture the effects...
Disability is an important and often overlooked component of diversity. Individuals with disabilities bring a rare perspective to science, technology, engineering, mathematics, medicine (STEMM) because their unique experiences approaching complex issues related health disability, navigating the healthcare system, creatively solving problems unfamiliar many individuals without disabilities, managing time resources that are limited by physical or mental constraints, advocating for themselves...
Abstract Although acute lymphoblastic leukemia (ALL) is most common in pediatric and adolescent young adult (AYA) patients, 20% of cases are diagnosed patients ≥ 55 years old. Use intensive regimens AYA populations has demonstrated excellent tolerability significant improvements event‐free survival (EFS) overall (OS). The backbone includes asparaginase corticosteroids, both which associated with more toxicity older those body mass index (BMI) 30 kg/m leads to poor tolerance these regimens....
Abstract The precision of human decisions is limited by both processing noise and basing on finite information. But what determines the degree such imprecision? Here we develop an efficient coding framework for higher-level cognitive processes, in which information represented a number discrete samples. We characterize sampling process that maximizes perceptual accuracy or fitness under often-adopted assumption full adaptation to environmental distribution possible, show how optimal differs...
138 Background: Immune checkpoint inhibitors (ICIs) are anti-cancer agents now in routine clinical practice, and may cause immune-related adverse events (irAEs). The proportion of inpatient admissions for irAEs, spectrum toxicities, management outcomes not well described. Methods: Patients with solid tumors admitted to the oncology service at a tertiary academic center over 3 months, were identified. Patient demographics, treatment details, irAE event data, collected those who received ICIs,...
Abstract Non-spatial attention is a fundamental cognitive mechanism that allows organisms to orient the focus of conscious awareness towards sensory information relevant behavioural goal while shifting it away from irrelevant stimuli. It has been suggested regulated by ongoing phase slow excitability fluctuations neural activity in prefrontal cortex, hypothesis challenged with no consensus. Here we developed and non-invasive stimulation paradigm aiming at modulating inferior frontal...
The ability to rapidly estimate non-symbolic numerical quantities is a well-conserved sense across species with clear evolutionary advantages. Despite its importance, the rapid representation and estimation of numerosity surprisingly imprecise biased. However, formal explanation for this seemingly irrational behavior remains unclear. We develop unified normative theory that parsimoniously incorporates in single framework information processing constraints alongside Brownian diffusion noise...
Reservoir computing is a powerful tool to explain how the brain learns temporal sequences, such as movements, but existing learning schemes are either biologically implausible or too inefficient animal performance. We show that network can learn complicated sequences with reward-modulated Hebbian rule if of reservoir neurons combined second serves dynamic working memory and provides spatio-temporal backbone signal reservoir. In combination memory, readout performs well FORCE learning,...
Disability is an important and often overlooked component of diversity. Individuals with disabilities bring a rare perspective to science, technology, engineering, mathematics, medicine (STEMM) because their unique experiences approaching complex issues related health disability, navigating the healthcare system, creatively solving problems unfamiliar many individuals without disabilities, managing time resources that are limited by physical or mental constraints, advocating for themselves...