A5008568216- Autophagy in Disease and Therapy
- Ferroptosis and cancer prognosis
- Endoplasmic Reticulum Stress and Disease
- Inflammasome and immune disorders
- Cancer, Lipids, and Metabolism
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Acute Ischemic Stroke Management
- Atherosclerosis and Cardiovascular Diseases
- Renin-Angiotensin System Studies
- Cardiovascular Function and Risk Factors
- Nuclear Receptors and Signaling
- RNA modifications and cancer
- Circadian rhythm and melatonin
- Parkinson's Disease Mechanisms and Treatments
- Epigenetics and DNA Methylation
- Iron Metabolism and Disorders
- Liver Disease Diagnosis and Treatment
- Sirtuins and Resveratrol in Medicine
- Vitamin C and Antioxidants Research
- S100 Proteins and Annexins
- Kawasaki Disease and Coronary Complications
- Advanced Glycation End Products research
- Advanced Proteomics Techniques and Applications
- Nanoparticle-Based Drug Delivery
University of Alabama at Birmingham
2023-2024
Wyoming Department of Education
2024
University of Wyoming
2020-2024
Zhongshan Hospital
2021-2023
Fudan University
2021-2023
Tabriz University of Medical Sciences
2019-2022
The First Affiliated Hospital, Sun Yat-sen University
2021-2022
Sun Yat-sen University
2021-2022
Ege University
2021
University of Tabriz
2021
Liver fibrosis is a life-threatening pathological anomaly which usually evolves into advanced liver cirrhosis and hepatocellular carcinoma although limited therapeutic option readily available. FUN14 domain containing 1 (FUNDC1) mitophagy receptor with little information in fibrosis. This study was designed to examine the role for FUNDC1 carbon tetrachloride (CCl4)-induced injury. GEO database analysis subsequent validation of biological processes including western blot, immunofluorescence,...
The mitophagy receptor FUNDC1 interacts with FBXL2 to preserve mitochondrial Ca 2+ homeostasis and cardiac function in obesity.
Mitochondrial Ca2+ overload contributes to obesity cardiomyopathy, yet mechanisms that directly regulate it remain elusive. The authors investigated the role of Parkin on obesity-induced cardiac remodeling and dysfunction in human hearts a mouse model 24-week high-fat diet (HFD) feeding. knockout aggravated HFD-induced dysfunction, mitochondrial overload, apoptosis without affecting global metabolism, blood pressure, aortic stiffness. deficiency unmasked decline voltage-dependent anion...