Fermentation of medicinal herbs can be a significant technique to obtain bioactive compounds. Paeoniae Radix (PR) used in the present study is well-known herbal medicine that exhibits anti-inflammatory and immunomodulatory activity. The aim this explore possibility compound newly generated PR extract by fermentation with plant-derived lactic acid bacteria

Six new dammarane-type triterpene diglycosides with a hydroperoxide group, floralginsenosides A, B, C, D, E, and F, were isolated from ginseng flower, the flower buds of Panax C. A. MEYER, together seven known oligoglycosides. The structures elucidated on basis chemical physicochemical evidence.

Five new dammarane-type triterpene glycosides, floralquinquenosides A, B, C, D, and E, were isolated from the flower buds of American ginseng, Panax quinquefolium L., together with 18 known glycosides 3 flavonoid glycosides. The structures elucidated on basis chemical physicochemical evidence.

Abstract magnified image The MeOH extract and its BuOH‐soluble fraction (crude saponin fraction) from the flower buds of Chinese tea plant ( Camellia sinensis (L.) O. Kuntze ; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice inhibitory against pancreatic lipase. From fraction, three new acylated oleanane‐type triterpene oligoglycosides, chakasaponins I, II, III 1 – 3 , resp.), isolated together with 13 known compounds. chemical structures...

The methanolic extract from the seeds of Psoralea corylifolia was found to inhibit production nitric oxide (NO) in lipopolysaccharide-activated mouse peritoneal macrophages. Among isolated compounds, bavachinin (IC50=26 μM), isobavachalcone (17 neobavaisoflavone (ca. 29 corylifol A 21 and psoralidin 23 μM) significantly inhibited accumulation nitrite (NO2−) as a marker NO. Bakuchiol, which is mainly contained extract, also showed weak activity at 10 μM, but cytotoxic effects were observed...

The oligoglycoside fraction from the flower buds of Panax ginseng C. A. MEYER (Araliaceae) was found to show protective effects on ethanol-induced gastric mucosal lesions in rats. From fraction, new dammarane-type triterpene tetraglycosides, floralginsenosides M, N, O, and P, were isolated together with major oligoglycosides ginsenoside Rd Re. structures elucidated basis chemical physicochemical evidence. Ginsenoside (protopanaxadiol 3,20-O-bisdesmoside) exhibited inhibitory ethanol-...

The ethyl acetate-soluble fraction of the methanolic extract from seeds Psoralea corylifolia was found to inhibit release β-hexosaminidase, as a marker antigen-IgE-induced degranulation in RBL-2H3 cells. Sixteen constituents were isolated and several constituents, Δ1,3-hydroxybakuchiol (IC50=49 μM), Δ3,2-hydroxybakuchiol (69 μM, bavachin (58 psoralidin (ca. 100 showed inhibitory activities against antigen-induced degranulation.

The methanolic extract from the leaves of Ilex paraguariensis (Aquifoliaceae) was found to show an inhibitory activity on porcine pancreatic lipase. From extract, three new triterpene oligoglycosides, mateglycosides A, B, and C, were isolated together with 18 known compounds. chemical structures oligoglycosides elucidated basis physicochemical evidence. Several constituents showed activities

The methanolic extracts from the wood and bark of Cotylelobium melanoxylon were found to inhibit plasma glucose elevation after sucrose loading in rats triglyceride olive oil mice. A new stilbene dimer, melanoxylin A, together with known dimers [(+)-ampelopsin F, (+)-isoampelopsin (+)-epsilon-viniferin] a trimer (vaticanol G) lignan [(+)-lyoniresinol] isolated extract, trimer, B, [(+)-epsilon-viniferin cis-(+)-epsilon-viniferin] trimers (vaticanols E, extract C. melanoxylon. principal...

As a part of our characterization studies on the bioactive saponin constituents tea flowers (Camellia sinensis, flower buds), methanolic extract and 1-butanol-soluble portion (the fraction) from buds were found to exhibit potent inhibitory effects ethanol- indomethacin-induced gastric mucosal lesions in rats serum glucose elevation sucrose-loaded rats. Among portion, floratheasaponins A, B, C showed gastroprotective hypoglycemic activities. Furthermore, we have developed qualitative...

The methanolic extract and its 1-butanol-soluble fraction from the flower buds of Camellia oleifera ABEL were found to exhibit inhibitory effects on ethanol- indomethacin-induced gastric mucosal lesions in rats. ethyl acetate- fractions also showed rat lens aldose reductase scavenging 1,1-diphenylpicryl-2-hydrazyl radical superoxide. From fraction, four new acylated oleanane-type triterpene oligoglycosides, yuchasaponins A, B, C, D, isolated their structures elucidated basis chemical...

Two acylated oleanane-type triterpene oligoglycosides, chakasaponins V and VI, an aromatic glycoside, chakanoside I, flavonol oligoglycoside, chakaflavonoside A, were isolated from the flower buds of Chinese tea plant [Camellia sinensis (L.) O. KUNTZE]. The chemical structures those new glycosides elucidated on basis physicochemical evidence.

New dammarane-type triterpene triglycosides, floralginsenosides G, H, I, J, K, La, and Lb, were isolated from the flower buds of Panax ginseng C

A new dammarane-type triterpene ketone, panaxadione, was isolated from the seeds of Panax ginseng C. A. MEYER (Araliaceae) together with two and lupane-type triterpenes, an aromatic oligoglycoside, three sterol glycosides, oligoglycosides (ginsenosides Rd, Re, Rg2). The structure a compound elucidated on basis physicochemical evidence. relative contents major ginsenosides in were compared those flesh parts young mature fruits.

Phytochemical investigation of the n-BuOH fraction mangrove plant Lumnitzera racemosa WILLD. (Combretaceae) led to isolation one new flavonoid glycoside; myrcetin 3-O-methyl glucuronate (1), phenolic lumniracemoside (2) and aliphatic alcohol n-hexanol 1-O-rutinoside (3), in addition seven known compounds (4–10). The structures these were determined by spectroscopic analyses (UV, IR, high resolution-electrospray ionization (HR-ESI)-MS, one- two-dimensional (1D- 2D)-NMR). Compound 7 showed...

Three new compounds were isolated from a MeOH extract of the leaves Syzygium samarangense, one cyanogenic glucoside, taxiphyllin 6'-O-gallate (1), megastigmane actinidioionoside (2), and sulfated flavonoid rhamnoside, myricetrin 2″-O-sulfate (3), together with 14 known compounds, lupeol (4), demethoxymatteucinol (5), cryptostrobin (6), betulinic acid (7), β-sitosterol glucoside (8), 2R-prunasin (9), myrciaphenone A (10), 1-feruloyl-β-D-glucopyranoside (11),...

Previous phytochemical investigations have revealed the presence of a variety compounds such as pyrrolidine derivatives, flavonoids, and megastigmanes in Egyptian plants. Onopordum alexandrinum has been traditionally used by natives for treatment skin cancers leprosy. In this paper isolation four new sesquiterpene–amino acid conjugates, onopornoids A–D (1–4), i.e., three elemanes one germacrane, acylated flavonoid glucoside (5) along with nine known (6–14) from whole aerial parts title plant...

A new lignan glucoside, officinalioside (1), was isolated from n-BuOH fraction of the aerial parts Borago officinalis L., together with four known compounds: actinidioionoside (2), roseoside (3), crotalionoside C (4) and kaempferol 3-O-β-D-galactopyranoside (5). The structure compound established by means spectroscopic chemical analyses. Compounds 1 2 showed a moderate DPPH radical scavenging activity (IC50: 52.6 ± 1.70 41.3 0.25 μM, respectively) comparable that standard trolox (16.6 2.2...

A lactic acid bacterium Lactobacillus paracasei IJH-SONE68, which was isolated from a fig leaf by our group, found to produce both acidic and neutral exopolysaccharides (EPSs). The nuclear magnetic resonance analysis demonstrates that the former EPS is composed primarily of mannose, latter one consists α-1, 6-linked glycan chains made N-acetylglucosamine (GlcNAc). presence GlcNAc polysaccharide first reported in prokaryotes. Furthermore, reveal EPS-biosynthetic gene organization IJH-SONE68...