Kingsley Adibe Mbachu

ORCID: 0000-0002-3702-1425
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry and Biological Activities
  • Click Chemistry and Applications
  • Microbial Applications in Construction Materials
  • Insect Resistance and Genetics
  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Ethnobotanical and Medicinal Plants Studies
  • Allelopathy and phytotoxic interactions
  • Peptidase Inhibition and Analysis
  • Insect Pest Control Strategies
  • Agricultural pest management studies
  • Phytochemical compounds biological activities

University of Ibadan
2017-2025

International Center for Chemical and Biological Sciences
2023

University of Karachi
2023

Background: Citrus limon seeds have limited exploration, compared to other parts. The increasing prevalence of mosquito menace prompted the investigation into repellent effects seed n-hexane extract and fractions (Rutaceae) against adult Anopheles gambiae sl mosquitoes. cytotoxicity chemical constituents 100% n-Hexane Fraction (HF) were also evaluated. Methods: Successive extraction was done with cold-maceration using, n-hexane, Ethyl Acetate (EA) methanol. three solvent extracts screened...

10.18502/ajmb.v17i1.17678 article EN Avicenna Journal of Medical Biotechnology 2025-01-25

Essential oils of air-dried samples leaf and stem Bryophyllum pinnatum obtained by hydro-distillation in an all glass clevenger-type apparatus gave percentage yield 0.14 0.55 respectively. The essential (EOs) were subjected to analysis using gas chromatography (GC), chromatography-mass spectrometry (GC-MS). Fifteen (15) compounds representing 97.78% B. oil seventeen (17) compounds, accounting for 97.23% identified. major present 1-octen-3-ol (19.52%), supraene (16.63%), 1-heneicosanol...

10.30574/gscbps.2019.9.2.0184 article EN GSC Biological and Pharmaceutical Sciences 2019-11-30

Fresh samples of leaves and roots Thunbergia grandiflora were collected from forest-reserved area, Ibadan, Nigeria for extraction their volatile oils.Hydro-distillation method was used in an allglass Clevenger apparatus designed to British pharmacopeia specifications.It gave yields 0.09% 0.10% respectively.The oils analyzed using gas chromatography [GC], chromatography-mass spectrometry [GC-MS] University Botswana.A total thirty-eight compounds identified the leaf root essential oils,...

10.9734/jamps/2017/35836 article EN Journal of Advances in Medical and Pharmaceutical Sciences 2017-01-10

In search of potent inhibitors cholinesterase enzymes and antioxidant agents, synthetic derivatives dihydroquinazolin-4(1H)-one (1?38) were evaluated as potential anti-Alzheimer agents through in vitro acetylcholinesterase (AChE) butyrylcholinesterase (BChE) inhibitions radical (DPPH ABTS) scavenging activities. The structure?activity relationship (SAR) was mainly based on the different substituents at aryl part which showed a significant effect inhibitory kinetic studies most active...

10.2298/jsc211106005b article EN cc-by Journal of the Serbian Chemical Society 2023-01-01

AbstractBridelia ferruginea Benth is a plant usually found in Savannah regions, used ethno-medicine for treatment of dysentery, elephantiasis, intestinal and bladder disorder. Chemical compounds present the leaf, twig, stem bark, wood root Bridelia essential oils, their antioxidant toxicity assays are been reported. The oils were obtained by hydro-distillation analysed means gas chromatography (GC) chromatography-mass spectrometry (GC-MS). assay was conducted using...

10.1080/0972060x.2023.2277902 article EN Journal of Essential Oil Bearing Plants 2023-11-02
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