A5051985633- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Traditional and Medicinal Uses of Annonaceae
- Essential Oils and Antimicrobial Activity
- Ethnobotanical and Medicinal Plants Studies
- Insect Pest Control Strategies
- Phytochemical compounds biological activities
- Plant biochemistry and biosynthesis
- Natural Antidiabetic Agents Studies
- Phytochemical Studies and Bioactivities
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemistry and Bioactive Compounds
- Moringa oleifera research and applications
- Helminth infection and control
- Allelopathy and phytotoxic interactions
- African Botany and Ecology Studies
- Seed and Plant Biochemistry
- Bioactive Compounds and Antitumor Agents
- Marine Sponges and Natural Products
- Agricultural pest management studies
- Phytochemistry and biological activity of medicinal plants
- Vanadium and Halogenation Chemistry
- Bioactive natural compounds
- Venomous Animal Envenomation and Studies
- Synthesis of Organic Compounds
University of Ibadan
2016-2025
University of Ilorin
2016
Johannes Gutenberg University Mainz
2010
University of Rostock
2010
Antioxidants are essential and important for plants animals’ sustenance. They substances that protect cells from the damage caused by unstable molecules known as free radicals. The sources origin of antioxidants which include fruits vegetables, meats, poultry fish were treated in this study. types such ascorbic acid, glutathione, melatonin, tocopherols tocotrienols reported. classification characteristics antioxidant; its measurements level food radicals also documented. Chemistry chain...
The n-butanol purified saponin extract of sorghum bicolor were screened for anti-bacterial activity against three pathogenic microbes; Escherichia coli, Staphylococcus aureus and Candida albicans. inhibited the growth S. aureus. It was concluded that saponins have inhibitory effect on gram-positive organism but not gram negative fungi.
Background: Citrus limon seeds have limited exploration, compared to other parts. The increasing prevalence of mosquito menace prompted the investigation into repellent effects seed n-hexane extract and fractions (Rutaceae) against adult Anopheles gambiae sl mosquitoes. cytotoxicity chemical constituents 100% n-Hexane Fraction (HF) were also evaluated. Methods: Successive extraction was done with cold-maceration using, n-hexane, Ethyl Acetate (EA) methanol. three solvent extracts screened...
Jatropha curcas is an ornamental plant which also employed to cure various infections in traditional medicine. The hexane, ethyl acetate and methanol extracts of this were analysed phytochemically screened against different microorganisms responsible for especially sexually transmitted diseases. Phytochemical analysis the revealed presence many secondary metabolites including steroids, alkaloids saponins. purified fractions displayed potent antimicrobial activity target organisms giving MIC...
Spirocurcasone (14), a diterpenoid possessing the unprecedented "spirorhamnofolane" skeleton, was isolated from root barks of Jatropha curcas, plant extensively cultivated throughout world, along with 11 known and two other new diterpenoids. The stereostructure spirocurcasone established using HRESIMS, NMR, quantum mechanical calculation electronic circular dichroic (ECD) spectrum. Some diterpenoids showed potent activity against L5178Y, mouse lymphoma cell line.
Extracts from Jatropha curcas, a plant used in African traditional medicine for various diseases, were tested cytotoxic activity. The root extracts strongly reduced cell growth of tumor cells vitro, result consistent with the knowledge application these medicine, especially to cure/ameliorate cancer. A selection pure diterpenoids existing species and isolated J. example, curcusone C, D, multidione, 15-epi-4Z-jatrogrossidentadion, 4Z-jatrogrossidentadion, 4E-jatrogrossidentadion,...
Plant extracts were evaluated on poultry bacteria known to be threatening public health. This is develop better bio-therapeutic agents from plant origin.Bacteria isolated water, feed, crop, gizzard and faeces of layer chicken. Isolates interest (Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa Klebsiella oxytoca) subjected antibiotic susceptibility test. Resistant strains further against different in comparison Meropenem (control) using agar diffusion method.E. coli had the...
Phytochemical investigation of the ethyl acetate extract root Mezoneuron benthamianum, a shrub commonly used as chewing stick in southwest Nigeria, led to isolation three compounds characterised trans-resveratrol, piceatannol and gallic acid by use spectroscopic techniques. The anticaries activity polyphenols was evaluated against four oral bacteria pathogens (Streptococcus mutans, Pseudomonas aeruginosa, Staphylococcus aureus Escherichia coli), isolated from clinical samples presented...
Hexane, chloroform and methanol extracts of the rootwood rootbarks Jatropha podagrica were studied for their antimicrobial activity against 18 organisms. All exhibited some broad spectrum antibacterial activity, at a concentration 20 mg/mL. The hexane generally more active than extracts. extract yellow rootbark was most all its comparable to that gentamycin but better with regard control S. aureus B. cereus. Three extracts, showed moderate antifungal yeast fungus, Candida albicans. Copyright...
Plant derived isoprenoids commonly called terpenoids, are not only useful as chemosytemic markers but increasingly attracting attention in the development of newer drugs for treatment multi-drug resistant tuberculosis. Anti-tuberculosis activity guided solvent fractionation and chromatographic separation chloroform extract S. guineense stem bark resulted isolation two bioactive 3-β-hydroxylupane-type isoprenoids: betulinic acid methylenediol ester (1) (MIC; 0.15 mg/mL) (2) 0.60 mg/mL). The...
In the present study, we have examined effects of an ethyl acetate extract ofMelaleuca bracteata on gastric acid secretion and indomethacin-induced ulceration. The plant is popularly known for its ornamental use in South Africa. Gastric was studied using modified method continuous while ulcers were produced albino rats by oral administration indomethacin. Results showed that, significantly reduced a dose-dependent fashion (P < 0.05). Similarly, animals pre-treated with misoprostol, mean...
Gakolanone (3',5'-digeranyl-2',4',6',3-tetrahydroxybenzophenone; 1), a novel benzophenone derivative was isolated from the hexane extract of Garcinia kola Heckel stem-bark along with three known 3-8'' linked biflavonoids: 3'',4',4''',5,5'',7,7''-heptahydroxy-3,8''-biflavanone (2); 3'',4',5,5'',5''',7,7''-heptahydroxy-4-methoxy-3,8''-biflavanone (3) and 4',4''',5,5'',7,7''-hexahydroxy-3,8''-biflavanone (4) ethanol extract. The compounds were characterized primarily using 1 D 2 nuclear...
The phytochemical investigation of the ethylacetate fraction an ethanolic extract obtained from stem bark Ficus sagittifolia (Moraceae) led to isolation four flavonoids: (2R)-eriodictyol (1), 2′- hydroxygenistein (2), erycibenin A (3), and genistein (4); a dihydrobenzofuran: moracin P (5); coumarin: peucedanol (6); apocarotenoid terpenoid: dihydrophaseic acid (7). These were identified via 1D 2D nuclear magnetic resonance spectroscopy (NMR) ultra-high-resolution liquid...
The vasoactive peptide bradykinin (BK) is an important member of the renin–angiotensin system. Its discovery tightly interwoven with snake venom research, because it was first detected in plasma following addition viper venom. While fact that venoms liberate BK from a serum globulin fraction well described, its destruction by has largely gone unnoticed. Here, found to be cleaved metalloproteinases Echis ocellatus, one deadliest snakes, which degraded dabsylated form (DBK) few minutes after...
The agropastoral farmers have employed Turraea vogelii (TVL), Senna podocarpa (SPL), and Jaundea pinnata (JPL) leaves for treating various diseases, including intestinal parasites in livestock the human population Nigeria. Gastrointestinal nematodes are highly significant to production people's health, natural products interesting as sources of new drugs. In this study, we evaluated effectiveness extracts derived from these plants parasitic infections using third-stage infective larvae (L3)...
The stem and root barks of Quassia undulata were exhaustively extracted with methanol to give the methanolic extracts: MeQuS MeQuR, respectively. chloroform extracts obtained fractionated on an open column silica gel by gradient elution chloroform–methanol mixtures. Purification fractions afforded isolation four compounds, namely: 3′-(8-hydroxy,6-methoxy,2-oxo-2H-1-benzopyran-7-yloxy)-3′,4′-dihydro, 7′-methoxy,2H-1-benzopyran (eniotorin) (1) a new bisbenzopyran coumarin,...