A5042518014- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Plant tissue culture and regeneration
- Synthesis and Reactions of Organic Compounds
- Pharmacological Effects of Natural Compounds
- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemicals and Medicinal Plants
- Medicinal Plants and Neuroprotection
- Synthesis of heterocyclic compounds
- Quinazolinone synthesis and applications
- Phytochemistry and Biological Activities
- Phenothiazines and Benzothiazines Synthesis and Activities
- Berberine and alkaloids research
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Plant biochemistry and biosynthesis
- Andrographolide Research and Applications
- Bioactive Compounds and Antitumor Agents
- Drug-Induced Hepatotoxicity and Protection
- Ethnobotanical and Medicinal Plants Studies
- Alkaloids: synthesis and pharmacology
- Phytochemistry and Bioactivity Studies
- Chemical synthesis and alkaloids
Central Institute of Medicinal and Aromatic Plants
2016-2025
Academy of Scientific and Innovative Research
2018-2025
Council of Scientific and Industrial Research
2006-2025
Baba Raghav Das Medical College
2025
ICAR Research Complex for NEH Region
2024
Birsa Agricultural University
2019-2024
Birla Institute of Technology and Science - Hyderabad Campus
2023
King George's Medical University
1987-2020
Jawaharlal Nehru Technological University, Hyderabad
2017
Kakatiya University
2009-2014
Abstract Not much is known about the mechanism of endophyte-mediated induction secondary metabolite production in Catharanthus roseus . In present study two fungal endophytes, Curvularia sp. CATDLF5 and Choanephora infundibulifera CATDLF6 were isolated from leaves plant that found to enhance vindoline content by 229–403%. The endophytes did not affect primary metabolism as maximum quantum efficiency PSII, net CO 2 assimilation, biomass starch endophyte-inoculated plants was similar...
Abstract Sweet basil (Ocimum basilicum) is well known for its diverse pharmacological properties and has been widely used in traditional medicine the treatment of various ailments. Although a variety secondary metabolites with potent biological activities are identified, our understanding biosynthetic pathways that produce them remained largely incomplete. We studied transcriptional changes sweet after methyl jasmonate (MeJA) treatment, which considered an elicitor metabolites, identified...
Abstract For the application of biochar in restoring pesticide-contaminated soils and minimizing risk associated with their uptake plants, it is crucial to understand impact on soil biological activities dissipation accumulation pesticides plant systems. In this study, effect Mentha -distilled waste-derived was investigated chlorpyrifos atrazine contaminated sandy loam soil. The four rates (2, 4, 6, 8 mg kg −1 ) 6 , 12 a single rate (4%) were used study. degradation pesticides, diversity...
Wounding is required to be made in the walls of green seed pod Opium poppy prior exudation latex. To withstand this kind trauma plants regulate expression some metabolites through an induced transcript level. 167 unique wound-inducible ESTs were identified by a repetitive round cDNA subtraction after 5 hours wounding Papaver somniferum seedlings. Further reverse northern analysis these revealed 80 transcripts showing more than two fold induction, validated semi-quantitative RT-PCR & real...
Biosynthesis of eugenol shares its initial steps with that lignin, involving conversion hydroxycinnamic acids to their corresponding coenzyme A (CoA) esters by 4-coumarate:CoA ligases (4CLs). In this investigation, a 4CL (OS4CL) was identified from glandular trichome-rich tissue Ocimum sanctum high sequence similarity an isoform (OB4CL_ctg4) basilicum. The levels OS4CL and OB4CL_ctg4-like transcripts were highest in O. trichome, followed leaf, stem root. content leaf essential oil positively...
Abstract Tissue specific biosynthesis of secondary metabolites is a distinguished feature medicinal plants. Withania somnifera , source pharmaceutically important withanolides biosynthesizes withaferin-A in leaves and withanolide-A roots. To increase the planta production, sustainable approach needs to be explored. Here, we isolated endophytes from different parts W. plants their promising role withanolide was established both in-vivo grown as well in-vitro raised composite Overall, fungal...
Aromatic ginger (Kaempferia galanga L) is native to India and believed be originated in Burma. Despite substantial uses a pickle south-east Asian cuisines, aromatic chemically less studied than white red ginger. Multi-directional investigations have been performed evaluate chemical composition, nutritional values, ameliorative protective potential of galanga) rhizome (KGR). Macro micro components analysis confirmed that KGR contains protein, fiber, high amount essential minerals (potassium,...
Abstract Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity drug resistant mutants Candida albicans at a minimum inhibitory concentration 31.25–250 µg/mL. Although the compound reported earlier , but this is first report its mutants. Copyright © 2009 John Wiley & Sons, Ltd.
Chemical characterization and acute sub-acute toxicity study of Trikatu, a generic herbal formulation Indian system medicine, was carried out in Charles Foster (CF) rats for safety profiling. In experiment, Trikatu at 2,000 mg/kg body weight once orally well tolerated by the experimental animals (both male female) no changes were observed mortality, morbidity, gross pathology, gain weight, vital organ hematological (total white blood cells (WBC) red (RBC) count), biochemical parameters such...