A5020219478- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Malaria Research and Control
- Medicinal Plants and Neuroprotection
- Phytochemicals and Medicinal Plants
- Natural Antidiabetic Agents Studies
- Drug-Induced Hepatotoxicity and Protection
- Bioactive Compounds and Antitumor Agents
- Phytochemicals and Antioxidant Activities
- Moringa oleifera research and applications
- Computational Drug Discovery Methods
- Phytochemical Studies and Bioactivities
- Bioactive natural compounds
- Ginseng Biological Effects and Applications
- Diverse Scientific Research Studies
- Dermatology and Skin Diseases
- Cholinesterase and Neurodegenerative Diseases
- Synthesis and biological activity
- Phytochemical compounds biological activities
- Pharmacological Effects of Medicinal Plants
- Chromatography in Natural Products
- Plant biochemistry and biosynthesis
- Plant tissue culture and regeneration
Central Institute of Medicinal and Aromatic Plants
2016-2025
Academy of Scientific and Innovative Research
2018-2025
Council of Scientific and Industrial Research
2022
University of Lucknow
2018
Centre de Recherche sur les Ions, les Matériaux et la Photonique
2012
National Centre for Genetic Resources and Biotechnology
2009
Indian Veterinary Research Institute
2004-2005
Committee on Publication Ethics
2005
α-(-)-bisabolol is a natural monocyclic sesquiterpene present in the essential oil has generated considerable interest chemical and pharmaceutical industries currently use various formulations, mainly cosmetics. This study was undertaken to evaluate its therapeutic profile against skin inflammation using in-vitro, in-vivo in-silico assays. Lipopolysachharide (LPS) 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced production of proinflammatory cytokines (TNF-α IL-6) macrophage cells as well...
Aromatic ginger (Kaempferia galanga L) is native to India and believed be originated in Burma. Despite substantial uses a pickle south-east Asian cuisines, aromatic chemically less studied than white red ginger. Multi-directional investigations have been performed evaluate chemical composition, nutritional values, ameliorative protective potential of galanga) rhizome (KGR). Macro micro components analysis confirmed that KGR contains protein, fiber, high amount essential minerals (potassium,...
Chemical characterization and acute sub-acute toxicity study of Trikatu, a generic herbal formulation Indian system medicine, was carried out in Charles Foster (CF) rats for safety profiling. In experiment, Trikatu at 2,000 mg/kg body weight once orally well tolerated by the experimental animals (both male female) no changes were observed mortality, morbidity, gross pathology, gain weight, vital organ hematological (total white blood cells (WBC) red (RBC) count), biochemical parameters such...
Aquilaria agallocha Roxb. family, Thymelaeaceae, is an evergreen plant of South-East Asia, commonly described as aloe wood or agarwood. Traditionally, the bark, root and heartwood are used for their medicinal properties a folk medicine hundreds years. Chemical analyses revealed that bulk oil constituted by agarospirol (12.5%), jinkoh-eremol (11.8%) hinesol (8.9%) major contributor. In present work, QSAR model antiinflammatory activity 10-epi-γ-Eudesmol, jinkoh-eremol, other compounds has...
Citronella essential oil (CEO) has been reported as an excellent mosquito repellent; however, mild irritancy and rapid volatility limit its topical application. It was aimed to develop a nonirritant, stable, consistent cream of CEO with improved residence time on skin using industrial approach. Phase inversion temperature technique employed prepare the cream. optimized characterized based sensorial evaluation, emulsification, consistency in terms softness, greasiness, stickiness, pH. The...
Capsazepine, an antagonist of capsaicin, is discovered by the structure and activity relationship. In previous studies it has been found that capsazepine potency for immunomodulation anti-inflammatory emerging as a favourable target in quest efficacious safe drug. Thus, 2D quantitative structural relationship (QSAR) model against tumor necrosis factor-α (TNF-α) was developed using multiple linear regression method (MLR) with good internal prediction (r2 = 0.8779) external (r2pred 0.5865)...
Abstract The effects of a 90‐day oral administration water and alcohol extracts dried calyx Hibiscus sabdariffa were evaluated in albino rats. Haematological, biochemical histopathological changes monitored every 30 days. death the animals was preceded by severe loss weight, accompanied with diarrhoea on 2000 mg/kg dose. There an increase food intake (g) per kg body weight day aqueous (A) ethanol (E) 300 extract groups. Significant reductions erythrocyte count no difference total leucocyte...
Eugenol is a phytochemical present in aromatic plants has generated considerable interest the pharmaceutical industries mainly cosmetics. A series of eugenol esters (ST1-ST7) and chloro (ST8) have been synthesized. The structures newly synthesized compounds were confirmed by 1H 13C NMR mass spectrometry. In an effort to evaluate pharmacological activity derivatives, we explored its anti-inflammatory potential against skin inflammation using in-vitro in-vivo bioassay. Synthesized derivatives...