A5065365693- RNA modifications and cancer
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Reproductive Physiology in Livestock
- Endoplasmic Reticulum Stress and Disease
- Tissue Engineering and Regenerative Medicine
- Ovarian function and disorders
- Reproductive Biology and Fertility
- Cardiovascular Function and Risk Factors
- Metabolism, Diabetes, and Cancer
- Congenital heart defects research
- Healthcare Systems and Public Health
- Nutrition and Health in Aging
- Ubiquitin and proteasome pathways
- Dialysis and Renal Disease Management
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
- Circular RNAs in diseases
- Peripheral Artery Disease Management
- Ferroptosis and cancer prognosis
- RNA Research and Splicing
Northwest A&F University
2025
Ministry of Agriculture and Rural Affairs
2025
Guizhou Provincial People's Hospital
2020-2024
Guizhou University
2020
Affiliated Hospital of Guizhou Medical University
2017
Guiyang Medical University
2017
Nanyang Medical College
2015
Abstract Ovarian superstimulation-ovum pick-up (OPU) technology facilitates the rapid propagation of animals with excellent genetic potential, substantially shortening interval between generations. Research regarding OPU implementation during voluntary waiting period (VWP), a phase potential for maximizing gains in high-yield herds, is limited. We aimed to optimize dosage and frequency follicle-stimulating hormone (FSH) injections postpartum cows develop an ovarian superstimulation protocol...
The proliferation and migration of vascular smooth muscle cells are significant in the development progression atherosclerosis plaque rupture. Metformin is a widely used antidiabetic drug, which has been reported to inhibit cell growth migration. antiproliferative antimigratory effects metformin have attributed 5' adenosine monophosphate-activated protein kinase (AMPK) activation. purpose present study was investigate on primary human aortic (HASMCs) vitro clarify underlying mechanism. We...
Metformin has been shown to inhibit the proliferation and migration of vascular wall cells. However, mechanism through which metformin acts on atherosclerosis (AS) via long non-coding RNA taurine up-regulated gene 1 (lncRNA TUG1) is still unknown. Thus, this research investigated effect lncRNA TUG1 AS.First, qRT-PCR was used detect expression in patients with coronary heart disease (CHD). Then, correlation between vitro their effects proliferation, migration, autophagy cells were examined....
Abstract Apoptosis of vascular endothelial cells (VECs) is highly important in the occurrence and development atherosclerosis (AS). HomeboxC6 (HOXC6) expressed higher levels multiple malignant tissues, it influences biological behavior cancer cells. However, effects HOXC6 on AS apoptosis VECs have not been fully elucidated. In this study, we demonstrated that expression was increased aortic wall rats peripheral blood monocytes patients with coronary heart disease. Furthermore, uncovered BAX...
Induction of cardiomyocyte (CM) proliferation is a promising approach for cardiac regeneration following myocardial injury. MicroRNAs (miRs) have been reported to regulate CM proliferation. In particular, miR‑449a‑5p has identified be associated with in previous high throughput functional screening data. However, whether regulates not thoroughly investigated. This study aimed explore modulates and identify the molecular mechanism via which The current demonstrated that expression levels were...
Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 ( EZR-AS1 ) is associated with coronary heart disease (CHD) remains unclear. Accordingly, aim present study was to evaluate role patients CHD venous endothelial cells (HUVECs). The findings revealed highly expressed peripheral blood CHD. In vitro experiments showed overexpression could enhance...
To explore the association between waist-to-height ratio (WHtR) and sarcopenic obesity (SO) in maintenance hemodialysis (MHD) patients with normal body mass index (BMI).
This study was to investigate the clinical features of chronic obstructive pulmonary disease (COPD) patients with concurrent acute myocardial infarction (AMI) and analyze occurrence in-hospital adverse events. Patients AMI who were admitted Beijing Chaoyang Hospital from January 2019 August 2023 retrospectively collected. All divided into COPD group simple according whether they COPD. received interventional treatment for AMI. The events compared between two groups. A total 183 aged...
Homeobox c6 (Hoxc6) affects the proliferation, migration, and infiltration of malignant tumor cells; however, effect Hoxc6 on atherosclerosis (AS) as well proliferation migration vascular smooth muscle cells (VSMCs), which play a role in promoting AS, has not yet been clarified. In present study, we tested hypothesis that rat VSMCs, hence is involved AS. The results showed expression mRNA protein was higher normal aortic wall than myocardium. Subsequently, model AS established by high-fat...
The clinical data of maintenance hemodialysis (MHD) patients from twenty centers in Guizhou province June to September 2020 were collected by cross-sectional study. divided into AFD group and non-AFD according whether had occurred. LTI was measured body composition monitor. results showed that the incidence 2 781 MHD 30.0% (835/2 781). Median level 15.2 (13.2, 17.5) kg/m2. higher than (P < 0.05). According tertiles LTI, low (LTI ≤ 13.9 kg/m2) highest (35.5%, 334/940), high lowest (26.3%,...