A5102898128- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Palliative and Oncologic Care
- Peripheral Artery Disease Management
- Healthcare during COVID-19 Pandemic
- Dysphagia Assessment and Management
- Obstructive Sleep Apnea Research
- Cancer Treatment and Pharmacology
- Cardiac, Anesthesia and Surgical Outcomes
- Infection Control and Ventilation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Occupational Health and Burnout
- Airway Management and Intubation Techniques
- Cardiovascular Health and Disease Prevention
- Pneumothorax, Barotrauma, Emphysema
- Nitric Oxide and Endothelin Effects
- Protein Degradation and Inhibitors
- Metabolism and Genetic Disorders
- Women's cancer prevention and management
- Oral health in cancer treatment
- Physical Education and Gymnastics
- Cancer Genomics and Diagnostics
- Long-Term Effects of COVID-19
Universidade Federal do Rio Grande do Sul
2022-2024
Universidade de Santa Cruz do Sul
2016-2022
Peninsula Health
2019
Alfred Health
2019
Monash University
2019
Universidade Federal do Pará
2012
Azienda Ospedaliera Treviglio
2004
Pierre Fabre (Germany)
2004
Goethe University Frankfurt
2004
Philipps University of Marburg
1998
4506 Background: The role of radiation therapy (RT) as part treatment for pancreatic cancer is uncertain in the post-gemcitabine era. primary endpoint this trial was to evaluate impact upon overall survival combination RT plus gemcitabine (G) versus G alone locally unresectable cancer. Methods: Patients (pts) with histologically proven, adenocarcinoma, PS <2, without prior chemotherapy or were eligible. Pts randomized ARM A: (1,000 mg/m2 weekly x 3 every 4 weeks) 7 cycles, B: (50.4 GY 28...
Abstract Hyperthyroidism is associated with elevated plasma levels of endothelium-derived proteins such as von Willebrand factor (vWF), fibronectin (FN) and endothelin-1 (ET-1). This study was designed to characterize the mechanisms involved in this phenomenon at cellular level. vWF, FN ET-1 secretion mRNA expression were measured human umbilical vein endothelial cells (HUVECs) exposed tri-iodothyronine (T 3 ) for 13 ± 1 days, using ELISA, Western blot, RIA Northern blot analysis...
9559 Background: A papulopustular rash (PPR) occurs in up to 90% of patients treated with epidermal growth factor receptor inhibitors (EGFRIs). These events lead decreased quality life, which dose modification or discontinuation 17% patients. This study examines factors associated dermatology-related QoL EGFRIs. Methods: We analyzed the results a dermatology-specific patient reported questionnaire, Skindex-16. Overall scores vary from 0 (best QoL) 96 (worst and are 3 domains: symptoms,...
Justification and objectives: In the search of strategies to treat acute respiratory failure caused by COVID-19, non-invasive ventilation (NIV) use prone position in spontaneous breathing appear. The objective is present case a patient with severe COVID-19 admitted an intensive care unit (ICU) who used adapted diving mask, which configured as innovative interface for NIV, position. Methods: Case report hospitalized diagnosed underwent early NIV means mask during 8 hours at night 6 day....
ABSTRACT Introduction: In obstructive sleep apnea syndrome (OSAS) there are obstructions in the upper airway that cause desaturations, disorders and an increased risk of involvement car accidents due to poor quality. The Mandibular Advancement Device (MAD) is one therapeutic alternatives for this syndrome. Objective: To evaluate effects MAD intercity public transport driver with OSAS. Methods: This a case report individual submitted period eight weeks. Epworth Sleepiness Scale,...
ABSTRACT This study aims to assess the effect of short-time low frequency inspiratory muscle trainer (Threshold IMT) on strength and electromyographic activity sternocleidomastoid (SCM) in people with chronic obstructive pulmonary disease (COPD). People COPD participating a lung rehabilitation program were allocated control or training (IMT) group. The group participated usual rehabilitation, whereas other received IMT (performed load 50% maximal pressure (MIP) adjusted weekly). Both...
Abstract Background Non-invasive ventilation (NIV) is indicated to avoid orotracheal intubation (OTI) reduce hospital stay and mortality. Patients infected by SARS-CoV2 can progress respiratory failure (RF); however, in the initial phase, they be submitted oxygen therapy NIV. Such resources produce aerosol cause a high risk of contagion health professionals. Safe NIV strategies are sought, therefore, authors adapted diving masks used as (called an Owner mask). Objective To assess mask safety...
Justificativa e Objetivo: Alguns agentes neoplásicos usados no tratamento do câncer (CA) causam toxicidade pulmonar outros importantes efeitos adversos, dessa forma, o presente estudo objetivou avaliar a presença de distúrbio ventilatório obstrutivo (DVO), restritivo (DVR) ou misto em pacientes com diagnóstico submetidos quimioterápico. Métodos: Trata-se transversal descritivo que avaliou à quimioterapia utilizando os fármacos Doxorrubicina, Bleomicina, Vimblastina, Dacarbazina,...
Objetivo: comparar o efeito agudo da eletroestimulação funcional (FES) e do exercício de plati/dorsi flexão tornozelo sobre fluxo arterial periférico indivíduos com Hipertensão Arterial Sistêmica (HAS) Diabetes Mellitus (DM) tipo II. Método: estudo crossover composto por portadores HAS DM controlada, ambos os sexos idade entre 45 a 70 anos. Avaliado Índice Tornozelo-Braquial (ITB) em membros superiores inferiores através esfigmomanômetro doppler vascular portátil, sendo avaliada presença...
Justificativa e objetivo: As doenças cardiovasculares (DCV) são consideradas umas das principais causas de morte em países desenvolvidos a cirurgia revascularização do miocárdio (CRM) se constitui indicação precisa para doença arterial coronariana (DAC). Sabe-se que periférica (DAP) está associada à presença DAC e, dessa forma, o objetivo estudo foi analisar fluxo periférico claudicação intermitente (CI) pacientes submetidos cardíaca (CC) com circulação extracorpórea (CEC). Métodos: Estudo...
Objetivo: avaliar o tipo de associação entre Índice Tornozelo-Braquial (ITB) e a presença claudicação intermitente em pacientes com Doença Pulmonar Obstrutiva Crônica (DPOC). Método: estudo transversal que avaliou 51 DPOC no período junho outubro 2015. O ITB foi avaliado nos membros superiores inferiores por meio esfigmomanômetro doppler vascular portátil, sendo classificado normal (1 1,40 mmHg), limítrofe (0,91 0,99 indicativo Arterial Periférica (DAP) < 0,90 mmHg, DAP leve (0,71...
Multiple endocrine neoplasia type 2 (MEN 2), an autosomal dominantly inherited cancer syndrome, is caused by mutations in the RET-protooncogene. The clinical manifestations include medullary thyroid carcinoma (MTC), pheochromocytoma and hyperparathyroidism.
Introdução: as cirurgias levam a resposta metabólica ao trauma, que é potencializada pelo jejum pré-operatório prolongado, dentre elas cirurgia cardíaca. Objetivo: verificar os valores de glicemia no transoperatório pacientes submetidos cardíaca, com abreviação do tempo pré-operatório. Método: tratou-se um estudo comparativo, não intervencionista em foram alocados grupo A (n=20) realizou convencional e B ingestão oral solução carboidratos (maltodextrina 12,5%) 2 horas antes da Resultados:...
7338 Background: The goals of chemotherapy in advanced NSCLC are to improve survival and palliate symptoms.This multinational phase II trial was designed evaluate a new schedule NVB oral combination with P followed by consolidation therapy as single agent NSCLC. Methods: Chemonaive stage III/IV patients (pts) were eligible receive 4 cycles P: 80 mg/m2 on d1 oral: 60 & d8 for the first cycle dose escalation at following absence grade 3–4 neutropenia. Pts objective response (OR) or stable...
Background: KappaMab is a chimeric IgG1 monoclonal antibody specific for Kappa Myeloma antigen (KMA), tumour cell exclusively expressed on the surface of kappa restricted MM cells. Early safety and efficacy signals seen with single-agent treatment in phase I/II studies conjunction observations that IMiD®-treatment upregulates KMA target enhances effector cytotoxicity, provide rationale this proof-of principal immune-oncology (IO) approach minimally pre-treated population. Aims: To establish...
7338 Background: The goals of chemotherapy in advanced NSCLC are to improve survival and palliate symptoms.This multinational phase II trial was designed evaluate a new schedule NVB oral combination with P followed by consolidation therapy as single agent NSCLC. Methods: Chemonaive stage III/IV patients (pts) were eligible receive 4 cycles P: 80 mg/m2 on d1 oral: 60 & d8 for the first cycle dose escalation at following absence grade 3–4 neutropenia. Pts objective response (OR) or stable...