A5064516294- Osteoarthritis Treatment and Mechanisms
- Proteoglycans and glycosaminoglycans research
- Nonmelanoma Skin Cancer Studies
- Allergic Rhinitis and Sensitization
- Dupuytren's Contracture and Treatments
- COVID-19 and healthcare impacts
- Cancer and Skin Lesions
- Orthopedic Surgery and Rehabilitation
- Cell Adhesion Molecules Research
- Tumors and Oncological Cases
- Peripheral Nerve Disorders
- Dermatology and Skin Diseases
- Vascular Tumors and Angiosarcomas
- Connective tissue disorders research
- Neurofibromatosis and Schwannoma Cases
- Cutaneous Melanoma Detection and Management
- Histiocytic Disorders and Treatments
- 3D Printing in Biomedical Research
- Glioma Diagnosis and Treatment
- Cellular Mechanics and Interactions
- Exercise and Physiological Responses
- Microtubule and mitosis dynamics
- Nanoparticle-Based Drug Delivery
- Knee injuries and reconstruction techniques
- Tuberous Sclerosis Complex Research
Stanford University
2017-2023
Palo Alto University
2023
Zonal organization plays an important role in cartilage structure and function, whereas most tissue-engineering strategies developed to date have only allowed the regeneration of with homogeneous biochemical mechanical cues. To better restore tissue there is a strong need engineer materials biomimetic gradient niche cues that recapitulate native organization. address this critical unmet need, study, we report method for rapid formation tissue-scale hydrogels as three-dimensional (3D) cell...
Cartilage tissue is characterized by zonal organization with gradual transitions of biochemical and mechanical cues from superficial to deep zones. We previously reported that 3D gradient hydrogels made polyethylene glycol chondroitin sulfate can induce zonal-specific responses chondrocytes, resulting in cartilage formation mimics native tissues. While the role cell–matrix interactions has been studied extensively, how cell–cell across different zones influence development remains unknown....
Brain cancer is a devastating disease given its extreme invasiveness and intricate location. Glioblastoma multiforme (GBM) one of the most common forms brain cancer, progression often correlated with significantly altered tissue stiffness. To elucidate effect matrix stiffness on GBM cell fates, previous research largely limited to 2D studies using immortalized lines, which has physiological relevance. The objective study develop gradient hydrogels brain-mimicking range as 3Din vitro model...
Articular cartilage is characterized by zonal organizations containing dual gradients of biochemical cues and mechanical cues. However, how gradient interacts with the to drive development remains largely unknown. Here, we report a dual-gradient hydrogel platform as 3D niche elucidate relative contributions in modulating zonal-specific chondrocyte responses organization. Chondroitin sulfate (CS), major constituent extracellular matrix, was chosen cue. Poly(ethylene glycol), bioinert polymer,...
This cohort study examines the odds of developing basal cell carcinoma, squamous or melanoma among insured adults with neurofibromatosis type 1.
Background: This study assessed whether adding trigger finger or carpal tunnel release at the time of thumb carpometacarpal (CMC) arthroplasty would increase postoperative opioid use, readmissions, complications, and development CRPS. Methods: Using IBM ® MarketScan Research Databases from 2012 to 2016, we identified a two groups CMC patients. The “CMC only” group only had on day operation. “multiple procedures” concurrent / release. Between groups, compared persistent 30-day diagnosis...
Abstract Background Elderly patients in senior communities faced high barriers to care during the COVID‐19 pandemic, including increased vulnerability COVID‐19, long quarantines for clinic visits, and difficulties with telemedicine adoption. Objective To pilot a new model of dermatologic overcome living pandemic assess patient satisfaction. Methods From 16 November 2020 9 July 2021, this quality improvement programme combined in‐residence full body imaging real‐time outlier lesion...
To the Editor: Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease affecting over 7% of US adults, with 40% having moderate-severe disease.1Fuxench Z.C.C. Block J.K. Boguniewicz M. et al.Atopic in America study: cross-sectional study examining prevalence and burden atopic adult population.J Invest Dermatol. 2019; 139: 583-590https://doi.org/10.1016/j.jid.2018.08.028Abstract Full Text PDF PubMed Scopus (215) Google Scholar Air pollution, specifically particulate matter...