Melissa Fernandes

ORCID: 0000-0002-3749-0176
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About
Contact & Profiles
Research Areas
  • Systemic Lupus Erythematosus Research
  • Inflammatory Bowel Disease
  • Systemic Sclerosis and Related Diseases
  • Pregnancy and Medication Impact
  • Atherosclerosis and Cardiovascular Diseases
  • Microscopic Colitis
  • Platelet Disorders and Treatments
  • Gastrointestinal motility and disorders
  • Pediatric Hepatobiliary Diseases and Treatments
  • Autoimmune and Inflammatory Disorders Research
  • Ocular Diseases and Behçet’s Syndrome
  • Genomics and Rare Diseases
  • Clinical Nutrition and Gastroenterology
  • Congenital gastrointestinal and neural anomalies
  • COVID-19 and healthcare impacts
  • Skin Diseases and Diabetes
  • Gallbladder and Bile Duct Disorders
  • Maternal and Neonatal Healthcare
  • Hemodynamic Monitoring and Therapy
  • Pancreatitis Pathology and Treatment
  • Renal Diseases and Glomerulopathies
  • Salivary Gland Disorders and Functions
  • Histiocytic Disorders and Treatments
  • Tourism, Volunteerism, and Development
  • Digestive system and related health

Boston Children's Hospital
2023

Hospital Curry Cabral
2017-2022

Hospital Vila Franca de Xira
2021

University of Toronto
2021

Connecticut Children's Medical Center
2020

UCSF Benioff Children's Hospital
2015-2018

University of California, San Francisco
2015-2018

Hospitais da Universidade de Coimbra
2018

National Institutes of Health
2015

ABSTRACT Objectives: We examined the fecal virome and bacterial community composition of children with Crohn disease (CD), ulcerative colitis (UC), healthy controls to test hypothesis that unique patterns viral organisms and/or presence pathogens may be identified could contribute pathogenesis pediatric inflammatory bowel (IBD). Methods: Fecal samples from 24 (mean 12.2 years) CD (n = 7) or UC 5) similar aged 12) were processed determine individual viromes. Viral sequences through translated...

10.1097/mpg.0000000000002140 article EN Journal of Pediatric Gastroenterology and Nutrition 2018-08-31

The COVID-19 pandemic has drastically changed healthcare systems and training around the world. Training Committee of North American Society for Pediatric Gastroenterology, Hepatology Nutrition sought to understand how affected pediatric gastroenterology fellowship training.A 21 question survey was distributed all 77 program directors (PDs) in director database via email on April 7. Responses collected through 19, 2020 were analyzed using descriptive statistics.Fifty-one (66%) PDs from...

10.1097/mpg.0000000000002768 article EN Journal of Pediatric Gastroenterology and Nutrition 2020-04-30

ABSTRACT Objectives: The aim of the study was to investigate value microscopic findings in classification pediatric Crohn disease (CD) by determining whether changes significantly with inclusion histologic findings. Methods: Sixty patients were randomly selected from a cohort studied at Pediatric Inflammatory Bowel Disease Clinic University California, San Francisco Benioff Children's Hospital. Two physicians independently reviewed electronic health records included determine Paris for each...

10.1097/mpg.0000000000000967 article EN Journal of Pediatric Gastroenterology and Nutrition 2015-09-02

A subset of children who receive a liver and/or kidney transplant develop de novo inflammatory bowel disease-like chronic intestinal inflammation, not explained by infection or medications, following transplant. We have conducted single-center, retrospective case series describing the unique clinical and histologic features this IBD-like inflammation solid organ At our center, nine 327 recipients developed IBD (six liver, two kidney, one liver-kidney). Most presented with prolonged...

10.1111/petr.12835 article EN Pediatric Transplantation 2016-11-11

A 5-month-old girl presented with 1 month of rectal bleeding, failure to thrive, and anemia. Appearing otherwise well, she was diagnosed as having cow's-milk protein allergy. Despite change elemental formula, symptoms persisted, severe anemia (hematocrit 22.3%) clinical findings worsening include cervical lymphadenopathy, hepatosplenomegaly, papular truncal rash, which had been eczema by a dermatologist. sigmoidoscopy showed nodular, erythematous rectosigmoid lesions, some central ulceration...

10.1097/mpg.0000000000000027 article EN Journal of Pediatric Gastroenterology and Nutrition 2013-12-17

Airway management is one of the most important anaesthetist's skills as major complications airway management, although rare, can be among life threatening in medicine. Crouzon syndrome a rare condition with physical characteristics that result difficult manipulation. A correct preanaesthetic evaluation and planned preinduction strategy should designed to facilitate intubation.

10.1136/bcr-2017-219371 article EN BMJ Case Reports 2018-05-30

<h3>Background:</h3> Anti-Ro52 antibodies are present in autoimmune connective tissue diseases (AICTD), as Sjögren's syndrome (SSj), systemic lupus erythematosus (SLE), sclerosis (SSc) or idiopathic inflammatory myopathies (IIM). antibody positivity (Ro52+) has been related to more severe clinical phenotypes, including interstitial lung disease (ILD). [1] The microcirculation involvement patients with anti-Ro52 is yet be disclosed. <h3>Objectives:</h3> aim of this study analyze the...

10.1136/annrheumdis-2024-eular.3122 article EN Annals of the Rheumatic Diseases 2024-06-01

The report highlights the importance of strict clinico-histological correlations when skin biopsies are performed in diagnostic doubt systemic lupus erythematosus. Furthermore, PUVA is never indicated autoimmune conditions involving photosensitivity, due to high potential for internal and cutaneous aggravation disease, as authors observed this case.

10.1002/ccr3.2105 article EN cc-by Clinical Case Reports 2019-03-22

Clinical outcomes in rheumatoid arthritis have greatly improved with therapeutic advances. Despite the availability of substantial clinical trial evidence, there is a lack real-life data. The aim this study was to assess disease status and quality life an outpatient population treated biological disease-modifying anti-rheumatic drugs.Cross-sectional recalling all patients ever our unit antirheumatic drugs. demographic data, compliance, activity, functional status, joint deformities,...

10.20344/amp.13605 article PT cc-by-nc-nd Acta Médica Portuguesa 2021-02-10

A 18-year-old woman with systemic lupus erythematosus (SLE) presented right sided migraine and blurred vision of the eye. Ophthalmologic evaluation revealed multiple bilateral exudative retinal detachments, increased choroidal thickness measured optical coherence tomography (OCT). Acute renal dysfunction contraindicated fluorescein or indocyanine green angiography. The presence choroidopathy was first presentation nephritis. She treated corticosteroids immunosuppressive agents resolution...

10.4172/2155-9570.1000729 article EN cc-by Journal of Clinical & Experimental Ophthalmology 2018-01-01

We aimed to identify features that allow differentiation of primary antiphospholipid syndrome (PAPS) patients suffer recurrent thrombotic events (RTE) despite anticoagulation, from the other diagnosed PAPS patients.This was an exploratory study anticoagulated attending Autoimmune Diseases Unit (1998-2018). From 2016, anti-phospholipid antibodies and lupus anticoagulant were determined for each patient at consecutive visits, collected together with retrospective clinical characteristics,...

10.1155/2022/7331586 article EN cc-by International Journal of Rheumatology 2022-11-10

Sicca symptoms, such as xerostomia and xerophthalmia, are prevalent in geriatric patients correlated toexhaustion low quality of life. Sjögren’s syndrome (SS), an autoimmune disorder characterized by lymphocyticinfiltration the exocrine glands, also exhibits xerophthalmia a main feature. In clinical practice,tools exist to assess disease activity severity symptoms Sjögren’s: EULAR SyndromeDisease Activity Index (ESSDAI) Syndrome Patient Reported (ESSPRI), respectively.Our objective is...

10.54646/bijgim.2022.03 article EN 2022-01-01
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