- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Animal Virus Infections Studies
- Viral Infections and Vectors
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Viral Infectious Diseases and Gene Expression in Insects
- Viral Infections and Immunology Research
- Microbial infections and disease research
- Milk Quality and Mastitis in Dairy Cows
- Virus-based gene therapy research
- Bacillus and Francisella bacterial research
- Identification and Quantification in Food
- Vector-borne infectious diseases
- Zoonotic diseases and public health
- Bacterial Genetics and Biotechnology
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- Systemic Sclerosis and Related Diseases
- Rabbits: Nutrition, Reproduction, Health
- Infectious Diseases and Mycology
- Animal Genetics and Reproduction
- Escherichia coli research studies
- Burkholderia infections and melioidosis
Karnataka Veterinary Animal and Fisheries Sciences University
2014-2024
Institute of Animal Health and Veterinary Biologicals
2007-2024
National Institute Of Veterinary Epidemiology And Disease Informatics
2017
M atrix metalloproteinases (MMPs) encompasses a family of secreted, calcium dependent, zinc containing endopeptidases.These enzymes are responsible for tissue remodelling and capable degrading all kinds extracellular matrix proteins including collagens, glycoproteins, gelatin, elastins, proteoglycans.MMPs involved in regulation cell behaviours like cellular differentiation, proliferation, angiogenesis, invasion, apoptosis.Thus, these have multi-factorial roles during tumor progression:...
The sequential pathology of Kyasanur forest disease (KFD) in mouse brain was assessed this study. virus (KFDV) strain P9605 used study confirmed by real-time reverse transcriptase-polymerase chain reaction targeting the NS5 gene. Mouse Lethal Dose 50 (MLD ) determined in-vivo mice inoculation test. One MLD KFDV inoculated intra-cerebrally into 36 aged 2–3 weeks. Another group age-matched that served as control were with plain media. Six each from infected and groups euthanized every 24 hrs...
We evaluated the safety and potency of Kyasanur Forest disease (KFD) vaccine inactivated with different formalin concentrations in mice, since side effects due to higher have been a major reason for refusal. Furthermore, an objective reduce use mice testing, we performed quantification KFD virus by real-time PCR compared it vivo titration mice. The prepared chicken embryo fibroblast cells was 0.04%, 0.06%, 0.08% formalin. 0.04% 0.06% failed test, whereas safe potent log protective index 5678...
Fifteen serotypes of E. coli isolated from poultry were subjected to RAPD-PCR using eight oligonucleotide random primers.Amplification with each the primers resulted in generation different DNA fingerprinting profile varied number bands.Dendrogram based clustering showed two major clusters.The polymorphic amplicons served as markers for species where unique serotypes.RAPD provided a rapid means discriminating and considered valuable tool molecular typing.
The present study reports the epidemiological and virological investigations of twelve different outbreaks Peste des Petits Ruminants (PPR) in goats sheep flocks with considerable morbidity mortality recorded from places Karnataka state India during 2014-2015.Clinical samples were collected affected or villages for laboratory investigation along parameters.The PPR virus (PPRV) antigen its genome detected infected tissues swab materials by sandwich enzyme-linked immunosorbent assay (s-ELISA)...
Brucellosis is a zoonotic and economically important disease of livestock. Pen side diagnostics are the need hour for rapid diagnosis brucellosis. The present study aimed to evaluate blood based lateral flow assay (LFA) with serum LFA rose bengal plate test (RBPT) Sera/blood samples [792: cattle, 153; buffalo, 55; sheep, 140; goats, 219; pigs, 225] were collected from Karnataka, India history repeat breeding, retention placenta abortion.The seropositivity brucellosis in goats pigs was 7.84,...
<h3>Background:</h3> Anti-Ro52 antibodies are present in autoimmune connective tissue diseases (AICTD), as Sjögren's syndrome (SSj), systemic lupus erythematosus (SLE), sclerosis (SSc) or idiopathic inflammatory myopathies (IIM). antibody positivity (Ro52+) has been related to more severe clinical phenotypes, including interstitial lung disease (ILD). [1] The microcirculation involvement patients with anti-Ro52 is yet be disclosed. <h3>Objectives:</h3> aim of this study analyze the...
Peste des petits ruminants (PPR), a viral disease of goats and sheep caused by morbillivirus the family paramyxoviridae is major threat to small ruminant farming.Global announcement PPR eradication 2030 has opened lot research gaps for development vaccines diagnostics differentiating infected vaccinated animals.With advent recombinant DNA technology, protein based and/or are being tested in various heterologous systems across globe diagnostic antigens.The proteins, virus like particle...
Following heavy rains and floods during October-November of 2019, outbreaks Bluetongue (BT) disease was witnessed in migratory sheep flood affected areas. The investigated fifteen flocks Karnataka state, involving a total 3575 with over 1480 ailing 428 deaths. Samples collected from 208 79 dead animals were initially subjected for NS1 genome based group specific virus (BTV) detection by Reverse Transcription-PCR (RT-PCR) later segment 2 serotype RTPCR. RT-PCR phylogenetic analysis confirmed...
Region wise monitoring of the PPR virus by active surveillance is essential as it aids in strategic planning measures disease control and prevention. The North Eastern Karnataka with sizable sheep goat population experiences outbreaks but attempts to isolate characterize prevailing limited. Hence, present research work was carried out objective isolation characterization isolates circulating microscopic (TEM) molecular (RT-PCR) methods. A total 15 suspected were attended different types...
Sugarcane press residue (SPR), a byproduct from sugar industry was evaluated for its nutritional worth as the non-conventional source of minerals well organic nutrients in 32-week-old white leghorn laying hens. Eight practical types isonitrogenous rations were prepared by incorporating SPR at 0, 5, 10 and 15 per cent either soya based or fish diets to form T1 T8 that order. Each diet assigned five replicates 4 hens each. The trial lasted 84 days. Results revealed cumulative average feed...