A5060534547- Nanoplatforms for cancer theranostics
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Luminescence and Fluorescent Materials
- Nanoparticle-Based Drug Delivery
- Atomic and Subatomic Physics Research
- Metal-Organic Frameworks: Synthesis and Applications
- Photodynamic Therapy Research Studies
- Renal and Vascular Pathologies
- Electronic and Structural Properties of Oxides
- Ocular Oncology and Treatments
- Advanced Nanomaterials in Catalysis
- Abdominal vascular conditions and treatments
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Carbon and Quantum Dots Applications
- Luminescence Properties of Advanced Materials
- Advanced MRI Techniques and Applications
- Advanced Photocatalysis Techniques
- Sulfur Compounds in Biology
- Cardiac Arrest and Resuscitation
- Radioactive element chemistry and processing
- Nanocluster Synthesis and Applications
Tianjin Medical University
2018-2025
Second Hospital of Tianjin Medical University
2023-2024
Abstract Persistent luminescence material (PLM)‐based photodynamic therapy (PDT) has shown tremendous promise in tumor elimination via avoiding continuous external light illumination. In addition, the tumor‐associated antigens produced by PDT can trigger systemic antitumor immune responses, but only exhibit a limited immunotherapy effect. Herein, persistent hydrogel is developed “turning solid into gel” strategy introducing PLM and an immunoadjuvant (R837) alginate‐Ca 2+ for rechargeable...
A persistent luminescent metal–organic framework (PLNPs@MIL-100(Fe)) was prepared via the layer-by-layer method for high spatial resolution MR imaging and autofluorescence-free NIR imaging-guided drug delivery.
Black titanium oxide has attracted tremendous interest in tumor phototherapy via converting light energy to heat and reactive oxygen species (ROS). Nevertheless, current synthesis methods suffer from inert gas shielding, high costs, complicated procedures, expensive facilities, which are fairly impractical for treatment application. Herein, we propose a one-step strategy fast facile of black TiO nanoparticles microwave-assisted hydrothermal approach with Ti power, hydrochloric acid,...
Digital subtraction angiography (DSA) is considered the "gold standard" for diagnosis of vascular diseases. However, contrast agents used in DSA are limited to iodine (I)-based small molecules, which unsuitable patients with contraindications. Here, iodine-free utilizing a bismuth (Bi) chelate, Bi-DTPA Dimeglumine, proposed visualization first time. Dimeglumine possesses simple synthesis process without need purification, large-scale production ability (over 200 g lab), superior X-ray...
Tantalum (Ta) emerges as a promising element for advanced computed tomography (CT) imaging probes owing to its high X-ray attenuation coefficient and excellent biocompatibility. Nevertheless, the synthesis of renally clear Ta-based through simple methods remains significant challenge. Herein, we introduce gram-scale approach renal-clearable Ta nanodots with water solubility CT in vivo. The nanodots, coordination polymers, are fabricated via reactions involving Ta(OH)5, citric acid (CA),...
The combination of microwave ablation (MWA) and chemodynamic therapy (CDT) presents a promising strategy for complete eradication residual tumor after MWA. However, it remains challenging urgent to develop facile, biocompatible, imaging-guided platform the achievement this goal. Herein, minimalist manganese hydrogel (ALG-Mn hydrogel) is proposed synergistic MWA CDT completely eradicate in vivo. ALG-Mn prepared using simple mixing method exhibits excellent syringeability, remarkable...
Abstract Enhanced computed tomography (CT) imaging with iodinated probes is widely utilized for the diagnosis and evaluation of various liver diseases. However, these iodine-based face intractable limitations including allergic reactions contraindications. Herein, we propose utilization renal-clearable iodine-free bismuth chelate (Bi-DTPA dimeglumine) non-invasive fast assessment hepatic ischemia–reperfusion injury (HIRI) via CT first time. Bi-DTPA dimeglumine offers several advantages such...