A5048548682- Advanced Nanomaterials in Catalysis
- Advanced Photocatalysis Techniques
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Electrocatalysts for Energy Conversion
- Nanoplatforms for cancer theranostics
- Domain Adaptation and Few-Shot Learning
- Sports injuries and prevention
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Extracellular vesicles in disease
- Graphene and Nanomaterials Applications
- Urticaria and Related Conditions
- Bone fractures and treatments
- Literature Analysis and Criticism
- Nanocluster Synthesis and Applications
- Intensive Care Unit Cognitive Disorders
- Extenics and Innovation Methods
- Anesthesia and Sedative Agents
- 2D Materials and Applications
- Edible Oils Quality and Analysis
- Photoacoustic and Ultrasonic Imaging
- Food Quality and Safety Studies
- 3D Printing in Biomedical Research
Sichuan University
1988-2025
West China Hospital of Sichuan University
2011-2025
Capital Medical University
2018
Engineering chem-/sono-/photo-multimodal antitumor therapies has become an efficient strategy to combat malignant tumors.
Abstract Critical‐size bone defects pose a formidable challenge in clinical treatment, prompting extensive research efforts to address this problem. In study, an inorganic–organic multifunctional composite hydrogel denoted as PLG‐ g ‐TA/VEGF/Sr‐BGNPs is developed, engineered for the synergistic management of defects. The demonstrated capacity mineralization, hydroxyapatite formation, and gradual release essential functional ions vascular endothelial growth factor (VEGF) also maintained...
Exploring multifaceted and highly sensitive biosensors is a major challenge in biotechnology medical diagnosis. Here, we create new iridium (Ir) cluster-anchored metal-organic framework (MOF, namely, IrNCs@Ti-MOF via coordination-assisted strategy) as peroxidase (POD)-mimetic nanoreactor for colorimetrically diagnosing hydrogen peroxide-related biomarkers. Owing to the IrNCs-N/O coordination of Ti-MOF unique enzymatic properties Ir clusters, exhibits exceptional exclusive POD-mimetic...
The healing of tendon injury is often hindered by peritendinous adhesion and poor regeneration caused the accumulation reactive oxygen species (ROS), development inflammatory responses, deposition type-III collagen. Herein, an extracellular vesicles (EVs)-cloaked enzymatic nanohybrid (ENEV) was constructed to serve as a multifaceted biocatalyst for ultrasound (US)-augmented matrix reconstruction immune microenvironment regulation. ENEV-based exhibits integrated merits treating injury,...
Abstract With the dramatic developments of renewable and environmental‐friendly electrochemical energy conversion systems, there is an urgent need to fabricate durable efficient electrocatalysts address limitation high overpotentials exceeding thermodynamic requirements facilitate practical applications. Recently, tellurium‐based nanomaterials (Te NMs) with unique chemical, electronic, topological properties, including Te‐derived nanostructures transition metal tellurides (TMTs), have...
Abstract The external‐stimulation‐induced reactive‐oxygen‐species (ROS) generation has attracted increasing attention in therapeutics for malignant tumors. However, engineering a nanoplatform that integrates with efficient biocatalytic ROS generation, ultrasound‐amplified production, and simultaneous relief of tumor hypoxia is still great challenge. Here, we create new semiconducting titanate‐supported Ru clusterzymes (RuNC/BTO) nanotherapies. morphology chemical/electronic structure...
Regenerating natural gradients of the tendon‒bone interface (TBI) is a major challenge in reconstruction rotator cuff tear (RCT). In this study, magnetic Janus hydrogel microrobots to match TBI orientation during RCT surgery are developed via biofriendly gas-shearing microfluidic platform. Through separate loading Mg2+ and Zn2+, facilitate immediate restoration long-term maintenance mineral gradient after implantation alignment through manipulation. vitro studies confirm spatiotemporal cell...
Abstract Postoperative adhesion (POA) is a common and serious complication following various types of surgery. Current physical barriers either have short residence time at the surgical site with low tissue attachment capacity or are prone to undesired formation owing double‐sided adhesive property, which limits POA prevention efficacy barriers. In this study, Janus‐structured microgels (Janus‐MGs) asymmetric capabilities fabricated using novel bio‐friendly gas‐shearing microfluidic...
Rheumatoid arthritis (RA), one of the systemic autoimmune diseases, features dysregulated inflammation that can eventually lead to multi-joint destruction and deformity. Although current clinical RA treatment agents including non-steroidal anti-inflammatory drugs, disease-modifying antirheumatic biological alleviate symptoms, there be long-term drug dependence considerable side effects. To promote course from resolution ultimately terminate vicious cycle recrudescence, it is important...
Abstract Background Performing total joint arthroplasty (TJA) in Parkinson’s disease (PD) patients may encounter a higher complication rate or worse functional outcomes compared with common patients. The relationship between PD and clinical after TJA is not fully understood. Methods Retrospectively , we used manual charts to investigate the 41 including 24 hip (THA) (28 hips) 18 knee (TKA) (22 knees) diagnosis of from 2009 2016. stage was confirmed by Hoehn Yahr scale. Prosthesis...
Dietary saturated fatty acids are always being hotly debated. Palm olein rich in (45.98%) is often considered as atherogenic nutritionally. There a lack of information on effects dietary oil by partially replacing with palm human health.A randomized controlled trial 88 participants has been conducted to elucidate the effect cardiovascular risk factors.By comparing soybean group (saturated amounted 23.31%) cocoa butter 93.76%), no significant difference was found (p > 0.05) physiological...
Compression therapy is commonly used to reduce lower limb swelling and blood loss after knee surgery. This study was performed investigate whether modified Robert Jones bandage (MRJB) as a postoperative compression necessary for enhanced-recovery primary total arthroplasty without the tourniquet application. In this prospective randomized controlled trial, 90 patients were grouped into 2 groups randomly. The experimental group received with MRJB from toes thigh 24 h control no therapy. Knee...
Abstract Background Patients with systemic lupus erythematosus are more likely to receive THA than the general population. However, it is controversial whether SLE increases risk of complications from THA. The purpose this retrospective study was reassess risks in patients under management model enhanced recovery after surgery. Methods diagnosed December 2011 2017 and treated were compared osteoarthritis. data extracted medical record system our department. chi-square test t-test used for...
To synthesize a Salphen-based Fe-N