- Ovarian function and disorders
- Sexual function and dysfunction studies
- Reproductive Biology and Fertility
- Orthopaedic implants and arthroplasty
- Microbial Natural Products and Biosynthesis
- Reproductive Health and Contraception
- Total Knee Arthroplasty Outcomes
- Neuroendocrine regulation and behavior
- Reproductive Health and Technologies
- Image and Video Quality Assessment
- Image Processing Techniques and Applications
- Healthcare and Venom Research
- Advanced Image Processing Techniques
- Orthopedic Infections and Treatments
- Sperm and Testicular Function
- Reproductive tract infections research
- Phytochemical compounds biological activities
- Surgical Sutures and Adhesives
- Attachment and Relationship Dynamics
- Prostate Cancer Diagnosis and Treatment
- Prenatal Substance Exposure Effects
- Organ Transplantation Techniques and Outcomes
- Fungal Biology and Applications
- Cardiovascular Issues in Pregnancy
- Dermatologic Treatments and Research
Westlake University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Zhejiang University
2024
University of Science and Technology of China
2024
Beijing University of Chinese Medicine
2024
West China Hospital of Sichuan University
2018-2023
Sichuan University
2018-2023
Oregon National Primate Research Center
2010-2017
Oregon Health & Science University
2010-2011
The incidence of cervical cancer ranks second among malignant tumors in women, exerting a significant impact on their quality life and overall well-being. hypoxic microenvironment plays pivotal role the initiation progression tumorigenesis. present study aims to investigate fundamental genes pathways associated with hypoxia-inducible factor (HIF-1A) cancer, aiming identify potential downstream targets for diagnostic therapeutic purposes.
Polyketides are a major class of natural products, including bioactive medicines such as erythromycin and rapamycin. They often rich in stereocenters biosynthesized by the ketoreductase (KR) domain within polyketide synthase (PKS) assembly line. Previous studies have identified conserved motifs KR sequences that enable bioinformatic prediction product stereochemistry. However, reliability applicability these methods not been thoroughly assessed. In this study, we conducted comprehensive...
Abstract Background Performing total joint arthroplasty (TJA) in Parkinson’s disease (PD) patients may encounter a higher complication rate or worse functional outcomes compared with common patients. The relationship between PD and clinical after TJA is not fully understood. Methods Retrospectively , we used manual charts to investigate the 41 including 24 hip (THA) (28 hips) 18 knee (TKA) (22 knees) diagnosis of from 2009 2016. stage was confirmed by Hoehn Yahr scale. Prosthesis...
Abstract Modular polyketide synthases biosynthesize structurally diverse natural products by a set of catalytic domains that operate in an assembly line fashion. Although extensive research has focused on the rational reprogramming modular synthases, little been attempted to introduce uncanonical reactions line. Here, we demonstrate insertion thioester reductase domain, which can generate terminal alcohol group instead canonical carboxylic acid, onto synthases. We show didomain acyl carrier...
Compression therapy is commonly used to reduce lower limb swelling and blood loss after knee surgery. This study was performed investigate whether modified Robert Jones bandage (MRJB) as a postoperative compression necessary for enhanced-recovery primary total arthroplasty without the tourniquet application. In this prospective randomized controlled trial, 90 patients were grouped into 2 groups randomly. The experimental group received with MRJB from toes thigh 24 h control no therapy. Knee...
Abstract Modular polyketide synthases (PKSs) are multidomain, assembly line enzymes that biosynthesize complex antibiotics such as erythromycin and rapamycin. The modular characteristic of PKSs has made them an ideal platform for custom production designer polyketides by combinatorial biosynthesis. However, engineered hybrid PKS pathways often exhibit significant loss enzyme activity, a general principle reprogramming not been established. Here we present strategy designing is applicable to...
This paper reviews the NTIRE 2024 Challenge on Shortform UGC Video Quality Assessment (S-UGC VQA), where various excellent solutions are submitted and evaluated collected dataset KVQ from popular short-form video platform, i.e., Kuaishou/Kwai Platform. The database is divided into three parts, including 2926 videos for training, 420 validation, 854 testing. purpose to build new benchmarks advance development of S-UGC VQA. competition had 200 participants 13 teams valid final testing phase....
The portal vein pressure higher than 10 mm Hg in patients with hepatic cirrhosis is more likely to have serious complications and poor prognosis. Nonselective receptor blockers (NSBBs) can reduce the pressure; however, efficacy safety of different NSBBs reducing were unconsistent. A systematic review meta-analysis was conducted evaluate carvedilol versus propranolol this study. We assessed Randomized controlled trials (RCTs) through PubMed, Web science, Embase, Cochrane library up January...