A5003921065- Gut microbiota and health
- Acupuncture Treatment Research Studies
- Diet and metabolism studies
- Nutritional Studies and Diet
- Ovarian function and disorders
- Genetic Neurodegenerative Diseases
- Complementary and Alternative Medicine Studies
- Reproductive Biology and Fertility
- Chromosomal and Genetic Variations
- Ovarian cancer diagnosis and treatment
- Healthcare and Venom Research
- Clostridium difficile and Clostridium perfringens research
- Food Security and Health in Diverse Populations
- Plant Disease Resistance and Genetics
- Oral microbiology and periodontitis research
- Ginseng Biological Effects and Applications
- Microbial Metabolites in Food Biotechnology
- Evolutionary Psychology and Human Behavior
- Botulinum Toxin and Related Neurological Disorders
- Ocular Diseases and Behçet’s Syndrome
- Antibiotics Pharmacokinetics and Efficacy
- Myofascial pain diagnosis and treatment
- Dietary Effects on Health
- Helicobacter pylori-related gastroenterology studies
- Image and Video Quality Assessment
Shanghai University of Traditional Chinese Medicine
2016-2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2024-2025
Shandong University of Traditional Chinese Medicine
2025
Ningbo University
2024-2025
Shanghai Traditional Chinese Medicine Hospital
2022-2025
First People's Hospital of Foshan
2022-2024
Fuzhou University
2024
Fujian Medical University
2023-2024
Qinghai University for Nationalities
2024
Zhejiang University
2020-2023
Pre-eclampsia (PE) is one of the malignant metabolic diseases that complicate pregnancy. Gut dysbiosis has been identified for causing diseases, but role gut microbiome in pathogenesis PE remains unknown.We performed a case-control study to compare faecal and normotensive pregnant women by 16S ribosomal RNA (rRNA) sequencing. To address causative relationship between PE, we used microbiota transplantation (FMT) an antibiotic-treated mouse model. Finally, determined translocation immune...
Abstract The gut microbiota has been implicated in glucose intolerance and its progression towards type-2 diabetes mellitus (T2DM). Relevant randomized clinical trial with prebiotic intervention was inadequate. We sought to evaluate the impact of fructooligosaccharides (FOS) galactooligosaccharides (GOS) on glycemia during oral tolerance test (OGTT) intestinal microbiota. A double-blind cross-over study performed 35 adults treated FOS GOS for 14 days (16 g/day). Faeces sampling, OGTT...
The metabolic syndrome (MetS) epidemic is associated with economic development, lifestyle transition and dysbiosis of gut microbiota, but these associations are rarely studied at the population scale. Here, we utilised Guangdong Gut Microbiome Project (GGMP), largest Eastern population-based microbiome dataset covering individuals different statuses, to investigate relationships between host physiology, diet, geography, physical activity socioeconomic status. At level, 529 OTUs were...
Oral mucositis is probably the most debilitating complication that can arise in treating a patient with head and neck cancer. Little known about impacts of oral microbiota on initiation progression mucositis.Based 16S rRNA gene sequencing, dynamic changes bacterial profile as well correlations between severity shifts during radiotherapy were investigated.Our results revealed community structure altered progressively radiation therapy, parallel marked increase relative abundance some...
Abstract Oscillospira is a common yet rarely cultivated gut bacterial genus. Recently human microbiota studies have demonstrated its underlying significance for host health. However, little known about -related information and the links between other members of microbial community. To study ecology gain insights into physiological conditions, we analyzed data from Guangdong Gut Microbiome Project, one largest database currently. Data 6376 participants were analyzed. We studied prevalence...
Desulfovibrio (DSV) is frequently found in the human intestine but limited knowledge available regarding relationship between DSV and host health. In this study, we analyzed large-scale cohort data from Guangdong Gut Microbiome Project to study ecology of associations health parameters. Phylogenetic analysis showed that piger might be most common abundant species GGMP. Predominant sub-OTUs were positively associated with bacterial community diversity. The relative abundance was correlated...
Little is known about the relationships between human genetics and airway microbiome. Deeply sequenced metagenomics, by simultaneously characterizing microbiome host genetics, provide a unique opportunity to assess microbiome-host genetic associations. Here we performed co-profiling of with identification over 5 million single nucleotide polymorphisms (SNPs) through deep metagenomic sequencing in sputum 99 chronic obstructive pulmonary disease (COPD) 36 healthy individuals. Host variation...
Abstract Background Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize temporal evolution of dysbiosis, relation phenotype systemic hepatic inflammatory responses leading HCC In present study, Mdr2 −/− mice were used as a model inflammation-based HCC. Gut composition function, addition serum LPS, cytokines/chemokines intrahepatic genes measured throughout course injury until Results Early stages...
Objective Long-term acupoint stimulation (LAS), also called embedding acupuncture, is a modified acupuncture technique. The preliminary results have demonstrated its efficacy in body-weight control. However, the low quality of available trials limited application. This study aimed to evaluate and safety LAS control by using randomized, parallel, sham-controlled clinical trial design. Methods was single-blind, including 84 adult participants (18–60 years) with body mass index (BMI) ≥ 24 kg/m...