- Gut microbiota and health
- Toxic Organic Pollutants Impact
- Microbial Community Ecology and Physiology
- Plant Molecular Biology Research
- Brucella: diagnosis, epidemiology, treatment
- Genomics and Phylogenetic Studies
- Probiotics and Fermented Foods
- Analytical chemistry methods development
- Wastewater Treatment and Nitrogen Removal
- Laser-induced spectroscopy and plasma
- Catalytic Processes in Materials Science
- Effects and risks of endocrine disrupting chemicals
- Clostridium difficile and Clostridium perfringens research
- Nutritional Studies and Diet
- Indoor Air Quality and Microbial Exposure
- Catalysts for Methane Reforming
- Plant Reproductive Biology
- Pharmaceutical and Antibiotic Environmental Impacts
- Diet and metabolism studies
- Air Quality and Health Impacts
- Carcinogens and Genotoxicity Assessment
- Environmental Toxicology and Ecotoxicology
- Mycobacterium research and diagnosis
- Ferroptosis and cancer prognosis
- Bacteriophages and microbial interactions
Southern Medical University
2015-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Guang’anmen Hospital
2021-2024
Shandong Provincial QianFoShan Hospital
2021-2024
Shandong First Medical University
2021-2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2024
South China Agricultural University
2005-2023
Shanghai Institute of Ceramics
2016-2022
Chinese Academy of Sciences
2015-2022
Institute of Genetics and Developmental Biology
2017-2022
Abstract Oscillospira is a common yet rarely cultivated gut bacterial genus. Recently human microbiota studies have demonstrated its underlying significance for host health. However, little known about -related information and the links between other members of microbial community. To study ecology gain insights into physiological conditions, we analyzed data from Guangdong Gut Microbiome Project, one largest database currently. Data 6376 participants were analyzed. We studied prevalence...
Grain size is an important agronomic trait affecting grain yield, but the underlying molecular mechanisms remain to be elucidated. Here, we isolated a dominant mutant, big grain3 (bg3-D), which exhibits remarkable increase of caused by activation PURINE PERMEASE gene, OsPUP4. BG3/OsPUP4 predominantly expressed in vascular tissues and specifically suppressed exogenous cytokinin application. Hormone profiling revealed that distribution different forms, roots shoots bg3-D altered. Quantitative...
A novel, compact, and green method was developed for the determination speciation analysis of mercury, based on flow injection photochemical vapor generation (PVG) coupled with miniaturized solution cathode glow discharge-atomic emission spectroscopy (SCGD-AES). The SCGD generated between a miniature hollow titanium tube emerging from glass capillary. Cold mercury (Hg(0)) by PVG subsequently delivered to excitation, finally signals were recorded spectrograph. detection limits (DLs) Hg(II)...
Summary Brassinosteroids (BRs) are a class of phytohormones that modulate several important agronomic traits in rice ( Oryza sativa ). GSK2 is one the critical suppressors BR signalling and targets transcription factors such as OsBZR1 DLT to regulate responses. Here, we identified OFP3 (OVATE FAMILY PROTEIN 3) an interactor both by yeast‐two‐hybrid screening demonstrated plays distinctly negative role While knockout promoted seedling growth, overexpression led strong insensitivity, which...
Fifteen bacterial strains isolated from molasses grass ( Melinis minutiflora Beauv.) were identified as nitrogen-fixers by using the acetylene-reduction assay and PCR amplification of nifH gene fragments. These classified a unique group insertion sequence-PCR fingerprinting, SDS-PAGE protein patterns, DNA–DNA hybridization, 16S rRNA sequencing morphological characterization. Phylogenetic analysis indicated that these diazotrophic belonged to genus Azospirillum closely related lipoferum (with...
Brassinosteroids (BRs) regulate important agronomic traits in rice, including plant height, leaf angle, and grain size. However, the underlying mechanisms remain not fully understood. We previously showed that GSK2, central negative regulator of BR signaling, targets DLT, GRAS family protein, to responses. Here, we identified Ovate Family Protein 1 (OFP1) as a DLT interacting protein. OFP1 was ubiquitously expressed protein localized both cytoplasm nucleus. Overexpression led enlarged...
The changes in the microbial community structure during acute exacerbations of severe chronic obstructive pulmonary disease (COPD) hospitalized patients remain largely uncharacterized. Therefore, further studies focused on temporal dynamics and sputum communities exacerbation COPD (AECOPD) would still be necessary. In our study, use molecular microbiological techniques provided insight into both fungal bacterial diversities AECOPD hospitalization. particular, we examined varieties lung 6...
Brassinosteroids (BRs) are a class of steroid hormones with great potential for use in crop improvement. De-repression is usually one the key events hormone signaling. However, how stability GSK2, central negative regulator BR signaling rice (Oryza sativa), regulated by BRs remains elusive. Here, we identify U-box ubiquitin ligase TUD1 as GSK2-interacting protein yeast two-hybrid screening. We show that able to directly interact GSK2 and ubiquitinate protein. Phenotypes tud1 mutant highly...
Desulfovibrio spp. is predominant member of sulphate‐reducing bacteria in human gut microbiota. Previous studies indicated that the isolation strains from faecal samples very important to study roles intestinal maintaining healthy states or causing diseases, as well defining their biological characteristics. However, there are few reports describing samples. In this study, were inoculated into various media containing different components. The enriched culture communities identified using...
Per- and polyfluoroalkyl substances (PFAS) can disrupt liver homeostasis. Studies have shown that a single exposure to PFAS may provoke abnormal function; however, few studies investigated the overall effect of mixtures. We aimed investigate associations between mixtures function indices explore relevant mechanisms. This study included 278 adult males from Guangzhou, China. Serum metabolite profiles were analyzed using untargeted metabolomics. applied weighted quantile sum (WQS) regression...
Three aniline-degrading bacteria, strains DN316(T), DN316-1 and DN365, were isolated from activated sludge. According to 16S rRNA gene sequence-based phylogenetic analysis, the isolates belonged genus Rhizobium, with Rhizobium ( = Agrobacterium) radiobacter LMG 140(T) as closest relative, 96.5 % sequence similarity. Phylogenetic analysis of representative strain DN316(T) using sequences glnA, thrC recA genes 16S-23S intergenic spacer region confirmed arrangement obtained gene. DNA-DNA...