Stephen M. Akers

ORCID: 0000-0002-3810-9656
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About
Contact & Profiles
Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Lung Cancer Diagnosis and Treatment
  • Ultrasound in Clinical Applications
  • Pleural and Pulmonary Diseases
  • Respiratory and Cough-Related Research
  • Neonatal and Maternal Infections
  • Various Chemistry Research Topics
  • Acute Lymphoblastic Leukemia research
  • Neonatal Respiratory Health Research
  • Sleep and Wakefulness Research
  • Mesenchymal stem cell research
  • Venous Thromboembolism Diagnosis and Management
  • Asthma and respiratory diseases
  • Neuroblastoma Research and Treatments
  • Skin and Cellular Biology Research
  • Delphi Technique in Research
  • Caveolin-1 and cellular processes
  • Central Venous Catheters and Hemodialysis
  • Antimicrobial Resistance in Staphylococcus
  • Hematopoietic Stem Cell Transplantation
  • Chronic Myeloid Leukemia Treatments
  • S100 Proteins and Annexins
  • Cardiovascular Effects of Exercise
  • Nerve injury and regeneration
  • Birth, Development, and Health

West Virginia University
2010-2022

Cooper University Hospital
1993-2017

Royal Brompton Hospital
2016

Rowan University
2015

Cancer Genetics (United States)
2010

Cooper Medical School of Rowan University
2006

Longwood University
2006

University Medical Center
1993-1995

University Hospital and Clinics
1993-1995

Graduate Hospital
1987-1992

The objective of the study was to prospectively evaluate an algorithmic approach cause(s) chronic dyspnea. MATERIALS/PATIENTS/METHODS: Prospective observational study. group consisted 123 patients with a chief complaint dyspnea unknown cause present for >8 weeks. Dyspnea severity scores were documented at entry and after therapy. Patients underwent Therapy could be instituted any time that data supported treatable diagnosis. Whenever possible, accuracy diagnosis confirmed improvement in...

10.1016/j.rmed.2010.12.009 article EN publisher-specific-oa Respiratory Medicine 2011-01-08

The host's response to infection is characterized by altered levels of neurotrophins and an influx inflammatory cells sites injured tissue. Progenitor that give rise the differentiated cellular mediators inflammation are derived from bone marrow progenitor where their development regulated, in part, cues stromal (BMSC). As such, alteration BMSC function elevated systemic has potential alter biologically relevant ways, including downstream cytokine production influences hematopoietic development.

10.1371/journal.pone.0009690 article EN cc-by PLoS ONE 2010-03-12

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of the Heat Combustion Biodiesel Using Bomb Calorimetry. A Multidisciplinary Undergraduate Chemistry ExperimentStephen M. Akers , Jeremy L. Conkle Stephanie N. Thomas and Keith B. Rider View Author Information Department Natural Sciences, Longwood University, Farmville, VA 23909Cite this: J. Chem. Educ. 2006, 83, 2, 260Publication Date (Web):February 1, 2006Publication History Received3 August 2009Published online1 February...

10.1021/ed083p260 article EN Journal of Chemical Education 2006-02-01

One prediction of the protease-antiprotease hypothesis chronic obstructive pulmonary disease (COPD) pathogenesis is appearance elastin-derived degradation products in plasmas affected patients that are due to breakdown alveolar interstitial elastin by an excess elastolytic activity lung. We previously demonstrated a significant elevation plasma peptides (EDP) subjects with COPD comparison asymptomatic smokers normal spirometry or nonsmokers. To better determine selectivity assay for EDP as...

10.1164/ajrccm/145.5.1077 article EN American Review of Respiratory Disease 1992-05-01

Hematopoietic reconstitution, following bone marrow or stem cell transplantation, requires a microenvironment niche capable of supporting both immature progenitors and cells with the capacity to differentiate expand. Osteoblasts comprise one important component this niche. We determined that treatment human primary osteoblasts (HOB) melphalan VP-16 resulted in increased phospho-Smad2, consistent TGF-β1 activity. This increase was coincident reduced HOB support B lineage chemotaxis adherence....

10.1371/journal.pone.0030758 article EN cc-by PLoS ONE 2012-02-17

ABSTRACT Low-density granulocytes (LDGs) are found abundantly in neonatal blood; however, there is limited mechanistic understanding of LDG interactions with bacteria and innate immune cells during acute infection. We aimed to determine how human LDGs may influence control the bacterial burden at sites infection, both individually presence mononuclear phagocytes. from umbilical cord blood do phagocytose Escherichia coli O1:K1:H7 traffic into acidic compartments. However, were significantly...

10.1242/jcs.252528 article EN Journal of Cell Science 2021-02-15

Late-onset sepsis caused by Staphylococcus aureus is a serious and relatively common complication encountered preterm neonates in NICUs. Typical treatment regimens for invasive methicillin-sensitive (MSSA) include semisynthetic beta lactam antibiotics, such as nafcillin. This report describes the first use of combination cefazolin ertapenem to successfully treat persistent MSSA bacteremia neonate who failed traditional first-line therapy.

10.5863/1551-6776-25.6.547 article EN The Journal of Pediatric Pharmacology and Therapeutics 2020-08-01

In Brief Dyspnea is a common and important symptom. A small number of categories disease cause the majority cases, but full differential diagnosis vast. Given large potential causes many possible diagnostic tests, an organized approach to workup dyspnea crucial. This article outlines spectrum dyspnea, relative use various suggests tiered diagnosis. For patients, disorders respiratory or cardiovascular systems, obesity, deconditioning, psychogenic are responsible. The is, however, extensive...

10.1097/01.cpm.0000218457.78185.5f article EN Clinical Pulmonary Medicine 2006-05-01

Epidermolysis bullosa rarely affects lower airways. We present a case of airway involvement and stenosis successfully managed with flexible bronchoscopy balloon dilation.

10.1002/rcr2.95 article EN cc-by-nc Respirology Case Reports 2015-02-16

<h3>Introduction</h3> Patients with interstitial lung disease (ILD) may develop airway abnormalities as part of their underlying condition, in response to fibrotic/tractional dilatation or a result repeated bronchiolar infection. While current practice guidelines recommend the provision pulmonary rehabilitation for ILD patients, no other interventions have been endorsed. We assessed symptomatic need patients clearance techniques (ACT’s) using visual analogue scale, and whether, those...

10.1136/thoraxjnl-2016-209333.309 article EN Thorax 2016-11-15
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