A5077915831- Peripheral Neuropathies and Disorders
- Amyotrophic Lateral Sclerosis Research
- Multiple Sclerosis Research Studies
- Peripheral Nerve Disorders
- Myasthenia Gravis and Thymoma
- Tactile and Sensory Interactions
- Parkinson's Disease Mechanisms and Treatments
- Neurogenetic and Muscular Disorders Research
- Smart Parking Systems Research
- Long-Term Effects of COVID-19
- Muscle activation and electromyography studies
- Systemic Lupus Erythematosus Research
- Botulinum Toxin and Related Neurological Disorders
- Immunotherapy and Immune Responses
- Acute Ischemic Stroke Management
- Wnt/β-catenin signaling in development and cancer
- Hereditary Neurological Disorders
- Intracranial Aneurysms: Treatment and Complications
- Radiation Dose and Imaging
- Indoor and Outdoor Localization Technologies
- Child Therapy and Development
- Molecular Biology Techniques and Applications
- Antifungal resistance and susceptibility
- Nerve injury and regeneration
- Art Therapy and Mental Health
Ewha Womans University
2020-2025
Toyo University
2019-2025
Xenobe Research Institute
2023
Seoul Medical Center
2012-2022
Yonsei University
2022
Seoul National University Hospital
2010-2021
National University College
2021
New Generation University College
2021
Hallym University
2021
Seoul National University Bundang Hospital
2021
Background and Purpose Middle East respiratory syndrome (MERS) has a high mortality rate pandemic potential.However, the neurological manifestations of MERS have rarely been reported since it first emerged in 2012. MethodsWe evaluated four patients with laboratory-confirmed coronavirus (CoV) infections who showed complications during treatment.These 4 were from cohort 23 treated at single designated hospital 2015 outbreak Republic Korea.The clinical presentations, laboratory findings,...
People with visual impairments face challenges when navigating indoor environments, such as train stations and shopping malls. Prior approaches either require dedicated hardware that is expensive bulky or may not be suitable for complex spaces. This paper aims to propose a practical solution enables blind travelers navigate station independently using smartphone without the need any special hardware. Utilizing Bluetooth Low Energy (BLE) technology smartphone's built-in compass, we developed...
To investigate the clinical relevance of CSF myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) testing in a large multicenter cohort.
Amidst growing concern about an increased risk of Guillain-Barré syndrome (GBS) following COVID-19 vaccination, clinical and electrodiagnostic features have not been fully characterized.We retrospectively reviewed medical records the patients diagnosed with GBS its variants vaccination at four referral hospitals during period mass program in South Korea (February to October 2021).We identified 13 post vaccination: AstraZeneca vaccine (Vaxzevria) 8, Pfizer-BioNTech (Comirnaty) 5. The mean...
Up-to-date, accurate information on the disease burden of motor neuron (MND) is cornerstone for evidence-based resource allocation and healthcare planning. We aimed to estimate MND globally from 1990 2019, as part Global Burden Disease, Injuries Risk Factor (GBD) study. Amyotrophic lateral sclerosis, progressive muscular atrophy, primary pseudobulbar palsy, spinal atrophy hereditary spastic paraplegia- were included analysis MNDs. measured age-standardized incidence, prevalence, death,...
Abstract The motor unit number index (MUNIX) refers to an electrophysiologic technique that measures the approximate of units using surface electromyographic interference pattern (SIP) recorded during voluntary contraction. This study was done assess reproducibility MUNIX performed on hypothenar muscles in 62 normal controls and 22 amyotrophic lateral sclerosis (ALS) patients. Inter‐ intraoperator correlation coefficients for were 0.74 0.86, respectively, controls, 0.95 0.93, ALS patients (...
Evaluation of a Radiation Dose Reduction Strategy for Pediatric Chest CTJee-Eun Kim1 2 and Beverley Newman1Audio Available | Share
We compared the levels of serum lipid, protein, and glucose between patients with amyotrophic lateral sclerosis (ALS) healthy controls.The lipids [including triglycerides, cholesterol, low-density lipoprotein (LDL), high-density (HDL)], 95 ALS (60 men) were those 99 age- sex-matched controls (64 men). Both groups had normal dietary intakes.Total cholesterol (p=0.004), LDL (p=0.040), triglyceride (p=0.025), protein (p=0.010) levels, LDL/HDL ratios (p<0.001) in men significantly lower than...
Background: The epidemiology of neuromyelitis optica spectrum disorder and multiple sclerosis varies depending on the region ethnicity. Objective: To estimate prevalence incidence in Korea during 2010–2016. Methods: We analyzed National Health Insurance research database, which contains single-payer health insurance data collected Korea. Neuromyelitis was defined based 2006 Wingerchuk criteria (for 2010–2015), 2015 International Panel for Optica Diagnosis 2016). Multiple by 2005 sclerosis....
Objectives This study aims to explore the effects of group art therapy on self-expression and positive peer relationship experiences children with borderline intellectual functioning. Methods The was conducted at Y Alternative School in Seoul, targeting 10 identified as showing Among them, 4 participants who consistently attended sessions were selected. over 16 sessions, once a week for 90 minutes, from August 23, 2023, December 18, 2023. divided into two groups, each led by therapists,...
Abstract BACKGROUND The role of the physician in end‐of‐life decision‐making is complicated. To analyze controversies that surround therapeutic and withholding life‐sustaining treatments, authors compared values regarding intervention were held by physicians family members patients with terminal malignancies. METHODS One hundred fourteen either advanced‐stage or disease enrolled current study. Questionnaires administered to duty patients' members. questions covered issues such as use new...
Ascorbic acid (Vitamin C) administration has been used to prevent infectious diseases in public or as a therapeutic agent by the physicians treatment of several diseases. is also involved immune cell functions and responses, although mechanisms which it exerts effects on cells against cancer are not fully understood at normal plasma level. In this study, we mice lacking l-gulono-γ-lactone oxidase (Gulo), enzyme required for biosynthesis ascorbic acid, characterize NK cytotoxicity ovarian...
Significance HYPONASTIC LEAVES 1 (HYL1)-CLEAVAGE SUBTILASE (HCS1) is a novel negative regulator of microRNA (miRNA) biogenesis that degrades HYL1 in the cytoplasm. Furthermore, cytoplasm CONSTITUTIVE PHOTOMORPHOGENIC (COP1) E3 ligase inhibit HCS1-mediated degradation. The COP1-HYL1-HCS1 network may integrate two essential cellular pathways: miRNA-biogenetic pathway and light signaling pathway. Our finding suggests regulatory system.
CT radiation dose is a subject of intense interest and concern, especially in children. Effective dose, summation whole-body exposure weighted by specific organ sensitivities, most often used to compute compare dose; however, there little standardization, are numerous different methods calculating effective dose. This study compares five such group children undergoing routine chest explores their advantages pitfalls.Patient data from 120 pediatric examinations were retrospectively calculate...
Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization nuclear such as transactive response DNA-binding protein 43 (TDP-43) and fused sarcoma (FUS) may be associated with neurotoxicity amyotrophic lateral sclerosis (ALS) frontotemporal lobar degeneration. This study investigated the changes distributions proteome transcriptome an vitro model ALS. After subcellular fractionation motor...
Acquired myasthenia gravis (MG) is a prototype autoimmune disease of the neuromuscular junction, caused in most patients by autoantibodies to muscle nicotinic acetylcholine receptor (AChR). There seem be ethnic and regional differences frequency clinical features MG seronegative for AChR antibody. This study aimed describe autoantibody profiles Korean with generalized A total 62 high index suspicion were identified from 18 centers, we examined their sera antibodies clustered AChR,...