A5053795005- Nanoplatforms for cancer theranostics
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Nanoparticle-Based Drug Delivery
- Resilience and Mental Health
- Career Development and Diversity
- Drug Transport and Resistance Mechanisms
- Heavy Metal Exposure and Toxicity
- Gender Diversity and Inequality
- MRI in cancer diagnosis
- Lung Cancer Treatments and Mutations
- Doctoral Education Challenges and Solutions
- Trace Elements in Health
- Grit, Self-Efficacy, and Motivation
- Epilepsy research and treatment
- Barrier Structure and Function Studies
- Emotional Intelligence and Performance
- Health and Well-being Studies
- HER2/EGFR in Cancer Research
- Iron Metabolism and Disorders
- Neuroscience and Neuropharmacology Research
- Ion channel regulation and function
West Virginia University
2016
West Texas A&M University
2011-2013
Texas Tech University
2011-2012
Texas Tech University Health Sciences Center
2011
The blood-brain barrier (BBB) is a specialized vascular interface that restricts the entry of many compounds into brain. This accomplished through sealing endothelial cells together with tight junction proteins to prevent paracellular diffusion. In addition, BBB has high degree expression numerous efflux transporters which actively extrude back blood. However, when metastatic lesion develops in brain vasculature typically compromised increases passive permeability (blood-tumor barrier; BTB)....
Abstract Tumors residing in the central nervous system (CNS) compromise blood–brain barrier (BBB) via increased vascular permeability, with magnitude of changes dependent on tumor type and location. Current studies determine penetrability a cancer therapeutic by administering progressively larger molecules until cutoff is observed where little to no accumulation occurs. However, decades-old experimental work mathematical modeling document methods calculate both size opening (pore) solute...
Strengths-based programs have emerged as asset-based approaches to professional development that promote positive student engagement and success. This paper shares the outcomes of a strengths-based program provided biomedical health sciences graduate doctoral students within an academic center. Program changes in participants’ perceived confidence when identifying applying their strengths different contexts were evaluated through mixed methods design included Likert-based survey thematic...
Purpose Strengths-based professional development has been associated with positive outcomes in academia and the organizational workplace. Students pursuing their doctoral degrees biomedical sciences US are often on graduate assistantships, where they experience an academic component to training integrated employee-like existence. The individual who serves as research advisor is supervisor, pays stipend. traditional structure poses unique challenges may be accompanied by stress, burnout...
Strengths-based coaching has emerged in past decades as an asset-based approach that can help individuals identify, harness, and leverage their strengths to achieve professional personal goals. This paper shares the design outcomes of a year-long strengths-based program support leadership development within context one university’s women’s initiative. Program changes participants’ perceived confidence identifying applying different contexts were evaluated through online survey using...
<p>Supplementary figures showing representative histology and tracer distribution in the brain tumor models.</p>
<div>Abstract<p>Tumors residing in the central nervous system (CNS) compromise blood–brain barrier (BBB) via increased vascular permeability, with magnitude of changes dependent on tumor type and location. Current studies determine penetrability a cancer therapeutic by administering progressively larger molecules until cutoff is observed where little to no accumulation occurs. However, decades-old experimental work mathematical modeling document methods calculate both size...
<div>Abstract<p>Tumors residing in the central nervous system (CNS) compromise blood–brain barrier (BBB) via increased vascular permeability, with magnitude of changes dependent on tumor type and location. Current studies determine penetrability a cancer therapeutic by administering progressively larger molecules until cutoff is observed where little to no accumulation occurs. However, decades-old experimental work mathematical modeling document methods calculate both size...
<p>Supplementary figures showing representative histology and tracer distribution in the brain tumor models.</p>