A5002043547- Phytoestrogen effects and research
- Glutathione Transferases and Polymorphisms
- Paraoxonase enzyme and polymorphisms
- Cancer, Lipids, and Metabolism
- Nutrition, Genetics, and Disease
- Cynara cardunculus studies
- Metabolism, Diabetes, and Cancer
- Cancer Genomics and Diagnostics
- Folate and B Vitamins Research
- Diet and metabolism studies
- Flavonoids in Medical Research
- Iron Metabolism and Disorders
- Alzheimer's disease research and treatments
- Endoplasmic Reticulum Stress and Disease
- Heavy Metal Exposure and Toxicity
- Peroxisome Proliferator-Activated Receptors
- Neurological and metabolic disorders
- Trace Elements in Health
- Phytochemicals and Antioxidant Activities
- Prostate Cancer Treatment and Research
- Digestive system and related health
- Drug Transport and Resistance Mechanisms
- Biological Research and Disease Studies
- Diet, Metabolism, and Disease
- Lung Cancer Treatments and Mutations
University of Saskatchewan
2018-2022
Texas Tech University Health Sciences Center
2012
Texas Tech University
2012
West Texas A&M University
2011
Systemic cytotoxic chemotherapy remains the mainstay of metastatic breast cancer; however, prognosis and overall survival is unfavorable due to inadequate treatment response and/or unacceptable toxicity. Natural compounds their active metabolites receive increasing attention as possible adjuvant therapy with cancer chemotherapeutics improve response, rates, quality life patients. This study investigated combination flaxseed lignans (Secoisolariciresinol Enterolactone) classic...
PC cells susceptible to androgen deprivation therapy (ADT) and relapse of aggressive resistant are a principal cause mortality. Cell metabolism plays key role in cancer prevention, treatment disease free survival. Naturally occurring polyphenolic lignans capable modulating serum hepatic cholesterol levels. Diverse plant lignanoid constituents can be precursors enterolactone (ENL) mammalian lignan. Despite the information gathered throughout years, effects mechanisms action bioactive (LN) not...
The limitations of anticancer drugs bespeak a need for multi‐target, yet safe approach that effectively thwarts cell survival adaptations. Tumor cells with endoplasmic reticulum (ER) stress evoke an adaptive mechanism, the unfolded protein response, survival. This has become promising drug target tumors upregulate synthesis and therefore depend on continuous folding to meet demand. Clear therapeutic prospects exist PPARγ inducing natural products given their multi‐target activity. PPARγ,...