A5047172385- Platelet Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood groups and transfusion
- Heparin-Induced Thrombocytopenia and Thrombosis
- Hemophilia Treatment and Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Mycobacterium research and diagnosis
- Venous Thromboembolism Diagnosis and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
Erasmus MC
2021-2024
Erasmus University Rotterdam
2021
Abstract There is significant ongoing debate regarding type 1 von Willebrand disease (VWD) defintion. Previous guidelines recommended patients with factor (VWF) levels <30 IU/dL be diagnosed VWD, whereas bleeding and VWF from 30 to 50 low VWF. To elucidate the relationship between VWD in context of age-induced increases levels, we combined data sets 2 national cohort studies: 162 Low Ireland Cohort (LoVIC) 403 The Netherlands (WiN) studies. In 47% participants, remained despite...
Patient-reported outcomes measurement information system (PROMIS) measures can be used to measure patient-reported outcomes. PROMIS measures, including computer adaptive tests (CATs) and short forms, have demonstrated the ability adequately assess in patients with hemophilia. It is, however, unclear if are suitable for von Willebrand disease (VWD), inherited platelet function disorders (IPFDs), rare bleeding (RBDs).
The population-based colorectal cancer (CRC) screening program in individuals aged 55 to 75 years the Netherlands uses fecal immunochemical testing (FIT), detect hemoglobin feces, followed by colonoscopy with a positive FIT.The objectives of this study are assess false-positive rate, detection and predictive value FIT for CRC advanced adenoma (AA) patients Von Willebrand disease (VWD) or hemophilia.We performed multicenter, nationwide cross-sectional embedded 2 studies on VWD hemophilia...
Abstract Introduction The severity of Von Willebrand disease (VWD) is currently based on laboratory phenotype. However, little known about the patient's experience with disease. most recent VWD guidelines highlight need for patient‐reported outcomes (PROs) in VWD. Aim study aimed to investigate patient‐perspective and identify key factors that determine experienced by patients. Materials methods Patients participated a nationwide cross‐sectional Netherlands (WiN‐study). filled questionnaire...
The negative impact of haemophilia on social participation is well established in previous studies, however, the Von Willebrand disease (VWD) has not been studied.To compare a large cohort VWD patients Netherlands with general Dutch population. In addition, to identify factors associated VWD.Patients participating "Willebrand Netherlands" study completed an extensive questionnaire educational level, absenteeism from school or work, and occupational disabilities.Seven-hundred eighty-eight...