A5077996137- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- Immunotherapy and Immune Responses
- Rabies epidemiology and control
- Monoclonal and Polyclonal Antibodies Research
- Advanced Biosensing Techniques and Applications
UK Health Security Agency
2023-2025
National Health Service
2023-2025
Manchester Academic Health Science Centre
2022
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified within the UK with no prior travel history to MPXV-endemic regions. Subsequently, case numbers exceeding 80,000 reported worldwide, primarily affecting gay, bisexual, and other men who have sex (GBMSM). Public health agencies worldwide offered IMVANEX Smallpox vaccination these individuals at high-risk provide protection limit spread MPXV. We developed comprehensive array ELISAs study poxvirus-induced...
In May, 2022, the first global outbreak of mpox (formerly known as monkeypox) occurred. response, public health agencies in UK have made smallpox vaccines available to individuals at highest risk infection. With cases still being detected globally, novel tools are required aid with diagnosis, serosurveillance, and evaluation immune responses following infection immunisation current new vaccine candidates. Here, we describe development a multiplexed immunoassay, MpoxPlex, able measure IgG 12...
Abstract In the summer of 2022, a large outbreak Monkeypox virus (MPXV) cases occurred globally. By December total 3,582 Mpox had been confirmed within UK. As result, Modified Vaccinia Ankara-Bavarian Nordic (“IMVANEX”) vaccine was offered to high-risk groups protect against spread virus. This led development multiple serological assays aid current understanding immunology. study assessed performance multiplexed solid-phase electrochemiluminescence (Meso Scale Discovery (MSD)) immunoassay...
Abstract In early 2022, a cluster of Monkeypox (now termed MPOX) virus (MPXV) cases were identified within the UK with no prior travel history to MPXV-endemic regions, suggesting localised transmission MPXV UK. Subsequently, in several other non-endemic countries and currently exceed 80,000 worldwide, primarily affecting gay, bisexual, men who have sex men. Public health agencies worldwide offered IMVANEX Smallpox vaccination these individuals provide protection limit spread MPXV. We...
Abstract The summer of 2022 saw the first global outbreak Mpox disease (formerly ‘monkeypox’), primarily within gay, bisexual, and other men who have sex with (GBMSM). In response, public health agencies in UK offered smallpox vaccines to those individuals deemed at highest risk infection. With cases still being detected globally, novel tools are required aid diagnosis, serosurveillance evaluation immune responses following infection vaccination. Here, we describe development a multiplexed...