A5025643559- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Computational Drug Discovery Methods
- Sulfur Compounds in Biology
- Analytical Chemistry and Sensors
- Toxic Organic Pollutants Impact
- Analytical Chemistry and Chromatography
- Plant-derived Lignans Synthesis and Bioactivity
- Drug-Induced Hepatotoxicity and Protection
- Pharmaceutical and Antibiotic Environmental Impacts
- Protein Hydrolysis and Bioactive Peptides
- Pituitary Gland Disorders and Treatments
- Nuclear Physics and Applications
- Lanthanide and Transition Metal Complexes
- Natural Compounds in Disease Treatment
- Pharmacological Effects of Natural Compounds
- Pharmacogenetics and Drug Metabolism
- Food Quality and Safety Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Phytoestrogen effects and research
- Pancreatic and Hepatic Oncology Research
- Advanced Proteomics Techniques and Applications
- Biochemical Acid Research Studies
- Cholinesterase and Neurodegenerative Diseases
China Pharmaceutical University
2016-2019
State Key Laboratory of Natural Medicine
2016-2017
A bidirectional route of communication between the gastrointestinal tract and central nervous system, termed "gut-brain axis," is becoming increasingly relevant to treatment cerebral damage. Panax Notoginsenoside extract (PNE) popular for prevention cardio-cerebrovascular ischemic diseases although plasma exposure levels are extremely low. To date, mechanisms underlying neuroprotective effects PNE remain largely unknown. In present study, were systematically studied via investigation...
Abstract Schisandra lignans, mainly including schizandrol A, B, schisantherin schizandrin etc., are the major active ingredients of chinensis . In present study, a robust liquid chromatography–tandem mass spectrometric (LC‐MS/MS) method was developed for simultaneous quantification schisandra lignans in rat primary hepatocytes. Lovastatin used as an internal standard, and chromatographic separation achieved on Shimadzu C 18 column with gradient elution at flow rate 0.2 mL/min. All analytes...
Abstract Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) is an excellent analytical technique for rapid analysis of a variety molecules with straightforward sample pretreatment. The performance MALDI‐TOF MS largely dependent on matrix type, and the development novel MALDI matrices has aroused wide interest. Herein, we devoted to seek more robust herbal saponins than previous reported, ginsenoside Rb1, Re, notoginsenoside R1 were used as model...