Bożena Michniak-Kohn

ORCID: 0000-0002-3858-158X
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Dermatology and Skin Diseases
  • Advanced Drug Delivery Systems
  • Essential Oils and Antimicrobial Activity
  • Drug Solubulity and Delivery Systems
  • Contact Dermatitis and Allergies
  • Bee Products Chemical Analysis
  • Surfactants and Colloidal Systems
  • Exercise and Physiological Responses
  • Muscle metabolism and nutrition
  • Crystallization and Solubility Studies
  • RNA Interference and Gene Delivery
  • Nail Diseases and Treatments
  • Nigella sativa pharmacological applications
  • Microencapsulation and Drying Processes
  • Lipid Membrane Structure and Behavior
  • Skin Protection and Aging
  • Phytochemicals and Antioxidant Activities
  • Toxin Mechanisms and Immunotoxins
  • Allergic Rhinitis and Sensitization
  • Therapeutic Uses of Natural Elements
  • Vitamin C and Antioxidants Research
  • 3D Printing in Biomedical Research
  • Curcumin's Biomedical Applications
  • Analytical Methods in Pharmaceuticals

Rutgers, The State University of New Jersey
2016-2025

University of Hertfordshire
2024

Analytical Services
2023

Rutgers Sexual and Reproductive Health and Rights
2014-2019

U.S. Army Research Institute of Environmental Medicine
2011

United States Army
2011

Weatherford College
2008

University Hospital, Newark
2005

University of South Carolina
1995-1998

Human skin not only serves as an important barrier against the penetration of exogenous substances into body, but also provides a potential avenue for transport functional active drugs/reagents/ingredients (topical delivery) and/or body (transdermal delivery). In past three decades, research and development in human equivalents have advanced parallel with those tissue engineering regenerative medicine. The are used commercially clinical substitutes models permeation toxicity screening....

10.3390/pharmaceutics4010026 article EN cc-by Pharmaceutics 2012-01-06

Thymoquinone (TQ) is a quinone-based phytochemical that was first identified in 1963 Nigella sativa (black cumin seed) by El-Dakhakhany. Based on the ideal characteristics of transdermal delivery, TQ potentially an attractive candidate for drug delivery. The aim this study to investigate feasibility delivery and assess effect ethanol propylene glycol donor solvent system along with various compositions receptor solvents. effects penetration enhancers vitro skin permeation absorption were...

10.1080/10717544.2018.1523256 article EN cc-by Drug Delivery 2018-01-01

Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of neurological disorder, epilepsy. The objective present study was to evaluate transdermal delivery OXC from microemulsions using different penetration enhancers. Transcutol® P (TRC), oleic acid (OA), cineole (cin), Labrasol (LS), Tween 80 (T80) and N-Methyl-Pyrrolidone (NMP) were used as enhancers well microemulsion components. Simple formulations in propylene glycol (PG) incorporating various combination also...

10.3390/pharmaceutics15010183 article EN cc-by Pharmaceutics 2023-01-04

Topical corticosteroids are used to treat a variety of skin conditions such as allergic reactions, eczema, and psoriasis. Niosomes novel surfactant-based delivery system that may be deliver desoximetasone via topical product application in order mitigate common side effects associated with traditional oral routes. The aim this research was identify the critical material attributes (CMAs) process parameters (CPPs) impact key characteristics drug-loaded niosomes using systematic quality by...

10.3390/pharmaceutics12030246 article EN cc-by Pharmaceutics 2020-03-09

The aim of this study was to develop lipid-based nanoparticles that entrapped a high concentration capsaicin (0.25%) from capsicum oleoresin extract. solid lipid (SLNs) and nanostructured carriers (NLCs) were strategically fabricated entrap without hazardous solvent. Optimized nanosize particles with entrapment loading capacity achieved pair-wise comparison the mixtures consisting fatty esters alcohols, representing small large crystal-structure molecules combined compatible liquid...

10.3390/pharmaceutics12050463 article EN cc-by Pharmaceutics 2020-05-19

The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure homogenization, without using organic solvents, were optimized the Taguchi design followed central composite design. exhibited a assay/drug content (0.6% w/w), solubility (6 × 105 times), and EE (75%) with particle size < 200 nm (PDI—0.143). safe (in vitro in vivo), photostable, autoclavable, stable up one year at 30 °C under...

10.3390/antiox10050725 article EN cc-by Antioxidants 2021-05-05
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