Pierre Autin

ORCID: 0000-0002-3866-0552
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About
Contact & Profiles
Research Areas
  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Silicon Carbide Semiconductor Technologies
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Cancer-related molecular mechanisms research
  • Histone Deacetylase Inhibitors Research

Nantes Université
2019-2022

Université d'Angers
2019-2022

Inserm
2019-2022

Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers
2022

Centre National de la Recherche Scientifique
2022

Longwood University
2017

Summary Adoptive transfer of T cells is a promising cancer therapy and expression chimeric antigen receptors can enhance tumour recognition T‐cell effector functions. The programmed death protein 1 ( PD 1) receptor prospective target for because ligands are expressed on many types, including lymphoma. Therefore, we developed murine (ch consisting the extracellular domain fused to cytoplasmic CD 3ζ. Additionally, therapies use various co‐stimulatory domains efficacy. Hence, inclusion Dap10 or...

10.1111/imm.12784 article EN Immunology 2017-07-03

DCMU [N-(3,4-dichlorophenyl)-N-dimethylurea] or diuron is a widely used herbicide, which can cause adverse effects on human, especially immune cells, due to their intrinsic properties and wide distribution. These cells are important for fighting not only against virus bacteria but also neoplastic cell development. We developed an approach that combines functional studies miRNA RNA sequencing data evaluate the of human response cancer, particularly one carried out by CD8+ T cells. found...

10.3389/fimmu.2022.925241 article EN cc-by Frontiers in Immunology 2022-07-28
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