- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
Swedish University of Agricultural Sciences
2013-2014
Recent advances in next-generation sequencing technology allow high-throughput cDNA (RNA-Seq) to be widely applied transcriptomic studies, particular for detecting differentially expressed genes between groups. Many software packages have been developed the identification of (DEGs) treatment groups based on RNA-Seq data. However, there is a lack consensus how approach an optimal study design and choice suitable analysis. In this comparative we evaluate performance three most frequently used...
Abstract Recent advances in next-generation sequencing technology allow high-throughput cDNA (RNA-Seq) to be widely applied transcriptomic studies, particular for detecting differentially expressed genes between groups. Many software packages have been developed the identification of (DEGs) treatment groups based on RNA-Seq data. However, there is a lack consensus how approach an optimal study design and choice suitable analysis. In this comparative we evaluate performance three most...
Mapping of chromosomal regions harboring genetic polymorphisms that regulate complex traits is usually followed by a search for the causative mutations underlying observed effects. This often challenging task even after fine mapping, as millions base pairs including many genes will typically need to be investigated. Thus trace mutation(s) there great efficient bioinformatic strategies. Here, we searched and regulating growth in Virginia chicken lines - an experimental population comprising...