A5067428228- Genetic and phenotypic traits in livestock
- Reproductive Physiology in Livestock
- Reproductive Biology and Fertility
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Genetic Associations and Epidemiology
- Effects of Environmental Stressors on Livestock
- Smart Agriculture and AI
- Ruminant Nutrition and Digestive Physiology
- Food Allergy and Anaphylaxis Research
- CRISPR and Genetic Engineering
- Animal Genetics and Reproduction
- Genetic Mapping and Diversity in Plants and Animals
- Prenatal Screening and Diagnostics
- Agroforestry and silvopastoral systems
- Allelopathy and phytotoxic interactions
- Tea Polyphenols and Effects
- Plant Disease Management Techniques
- Forest Management and Policy
- Epigenetics and DNA Methylation
- Pharmacological Effects and Assays
- Statistical Methods and Bayesian Inference
- dental development and anomalies
- Reproductive System and Pregnancy
- Plant and Fungal Interactions Research
University of Missouri
2007-2025
University of Missouri Health System
2022-2023
Missouri College
2007
National Institute of Environmental Health Sciences
2006
National Cancer Institute
2006
Texas A&M University
2004
<title>Abstract</title> Although social determinants of health (SDH) significantly impact outcomes, reliable data on SDH has not been widely accessible. Despite recent efforts to integrate more individual-level (I-SDH) into electronic records, the available sources that can be accessed at scale remain predominantly community-level, structured (S-SDH). An alternative, though underutilized, strategy for collecting is link with third-party consumer databases have accumulated socioeconomic...
Case-control studies of unrelated subjects are now widely used to study the role genetic susceptibility and gene-environment interactions in etiology complex diseases. Exploiting an assumption independence, treating distribution environmental exposures as completely nonparametric, Chatterjee Carroll recently developed efficient retrospective maximum-likelihood method for analysis case-control studies. In this article, we develop extension approach where information may be missing on some...
Establishment and maintenance of pregnancy in the pig is a complex process that relies on conceptus regulation maternal proinflammatory response to endometrial attachment. Following elongation, conceptuses secrete interferon gamma (IFNG) during attachment luminal epithelium. The objective here was determine if production IFNG important for early development establishment pregnancy. CRISPR/Cas9 gene editing somatic cell nuclear transfer technologies were used create an loss-of-function study...
<i>Background:</i> Racemic (<i>R</i>,<i>S</i>)-albuterol is a 1:1 mixture of an <i>R</i>-enantiomer which has bronchodilatory and anti-inflammatory effects, <i>S</i>-enantiomer associated with increased airway hyperreactivity proinflammatory effects. Proinflammatory effects regularly inhalated <i>S</i>-albuterol have not been studied in whole-animal model. We hypothesized that regular administration...
Pig conceptuses secrete estrogens (E2), interleukin 1 beta 2 (IL1B2), and prostaglandins (PGs) during the period of rapid trophoblast elongation establishment pregnancy. Previous studies established that IL1B2 is essential for conceptus elongation, whereas E2 not or early maintenance corpora lutea. The objective present study was to determine if expression prostaglandin-endoperoxide synthase (PTGS2) release PG are important development To understand role PTGS2 in pregnancy establishment, a...
Abstract In vitro production (IVP) of embryos in cattle can result large/abnormal offspring syndrome (LOS/AOS) which is characterized by macrosomia. LOS cause dystocia and lead to the death dam calf. Currently, no test exists identify pregnancies. We hypothesized that fetal ultrasonography and/or maternal blood markers are useful LOS. Bovine fetuses were generated artificial insemination (control) or IVP. Fetal ultrasonographies taken on gestation D55 (D55) collections performed D56 D105...
The first week of gestation is a period major pregnancy loss in cattle, this study reveals that the male plays key role regulating embryonic development during time.The impact sire on preimplantation cattle remains poorly understood. This evaluated differences embryos produced vitro from sires with varying capacities to produce blastocysts. Sires classified as high (HP) and low performing (LP) based their ability were used better understand how regulates development. By monitoring...
Abstract Objective —To determine whether oral administration of cyproheptadine or cetirizine blocks the action serotonin and histamine, respectively, results in diminished eosinophilic airway inflammation cats with experimentally induced asthma. Animals —9 which asthma was through exposure to Bermuda grass allergen (BGA) during a 3-month period. Procedures —Cats were randomized receive monotherapy each 3 treatments for 1 week: placebo (flour gelatin capsule, PO, q 12 h), (8 mg, (5 h). A...
Summary It is widely believed that risks of many complex diseases are determined by genetic susceptibilities, environmental exposures, and their interaction. Chatterjee Carroll (2005, Biometrika 92, 399–418) developed an efficient retrospective maximum‐likelihood method for analysis case–control studies exploits assumption gene–environment independence leaves the distribution covariates to be completely nonparametric. Spinka, Carroll, Genetic Epidemiology 29, 108–127) extended this approach...
In 2017 a survey was initiated of vineyards throughout Missouri for the presence 19 different grapevine viruses. A total 400 samples were collected from 25 grape cultivars, with sample consisting 16 petioles (four four vines). Sampling within vineyard blocks random, without regard to or absence symptoms. After nucleic acids extracted petiole samples, acid analyzed using reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) detect viral RNA/DNA. At least one virus detected in...
Ectodermal dysplasias (EDs) are a heterogeneous group of genetic conditions affecting the development and/or homeostasis two or more ectodermal derivatives, including hair, teeth, nails, and certain glands. There currently 49 recognized EDs with molecularly confirmed etiology. The very rare disorders, individually in aggregate. Very little is published regarding prevalence these disorders. As result genomics revolution, diseases have emerged as global health priority. various disabilities...
Abstract In 2016 and 2017, 98 separate commercially available bird feed mixes were examined for the presence of weed seed. All seed contaminants counted identified by species. Amaranthus species present in 94 bags feed. included waterhemp [ tuberculatus (Moq.) Sauer], redroot pigweed ( retroflexus L.), Palmer amaranth palmeri S. Watson), smooth hybridus tumble albus L.). was 27 mixes. Seed common ragweed Ambrosia artemisiifolia kochia Bassia scoparia (L.) A.J. Scott], grain sorghum Sorghum...
Abstract Eight different roast profiles for each of the three origins cacao were prepared and made into unsweetened chocolate based upon an I‐Optimal response‐surface design minimizing prediction variance. Quantitative chemical analysis all treatments was performed with HPLC‐DAD on six important bitter compounds (i.e., theobromine, caffeine, epicatechin, catechin, procyanidin B2, cyclo(Proline‐Valine)). Least‐squares linear modeling then performed. Using derived models, contour plots...
Serum supplementation during bovine embryo culture has been demonstrated to promote cell proliferation and preimplantation development. However, these desirable outcomes, have associated with gene expression alterations of pathways involved in macroautophagy, growth, development at the blastocyst stage, as well developmental anomalies such fetal overgrowth placental malformations. In order start dissecting molecular by which serum medium stage promotes abnormalities, we examined morphometry,...
Highlights A machine learning framework estimated residue cover in RGB images taken at three resolutions from 88 locations. The best results primarily used texture features, the RFE-SVM feature selection method, and SVM classifier. Accounting for shadows plants plus modifying optimizing features may improve performance. An automated system developed using is a viable strategy to estimate obtained with handheld or UAV platforms. Abstract . Maintaining plant on soil surface contributes...
Abstract An experiment was designed to compare the recently developed 7 & Synch and 7-day CO-Synch + CIDR protocols for synchronization of estrus among beef cows prior fixed-time artificial insemination (FTAI) with conventional or sex-sorted semen. Bos taurus (n = 1538) were blocked based on age days postpartum (DPP) randomly assigned protocol semen type. Cows treated 769) received administration gonadotropin-releasing hormone (GnRH; 100 μg gonadorelin) insertion a 1.38 g intravaginal...