- melanin and skin pigmentation
- Dermatologic Treatments and Research
- Skin Protection and Aging
- Cutaneous lymphoproliferative disorders research
- Autoimmune Bullous Skin Diseases
- Dermatological and Skeletal Disorders
- Genetic and rare skin diseases.
- Psoriasis: Treatment and Pathogenesis
- Cancer and Skin Lesions
- Facial Rejuvenation and Surgery Techniques
- Acne and Rosacea Treatments and Effects
- Laser Applications in Dentistry and Medicine
- Wound Healing and Treatments
- Systemic Sclerosis and Related Diseases
- Mast cells and histamine
- Eosinophilic Disorders and Syndromes
- Fungal Infections and Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Milk Quality and Mastitis in Dairy Cows
- Vascular Tumors and Angiosarcomas
- Pharmacological Effects of Natural Compounds
- Cardiac tumors and thrombi
- Hedgehog Signaling Pathway Studies
- Dermatological and COVID-19 studies
- Veterinary Oncology Research
Cairo University
1978-2023
Creative Commons
2022
National Research Centre
1978
Background Keloids and hypertrophic scars are challenging to both patients physicians. They can be aesthetically disfiguring, functionally debilitating, emotionally distressing. Lasers have introduced new mechanisms improve on aesthetic symptomatic levels. Aim of Work Comparing the efficacy fractional CO 2 laser, long‐pulsed Nd:YAG laser their combination in treatment keloids clinical, histopathological, biochemical basis. Patients Methods Thirty with were enrolled study. Three each patient...
NB-UVB has long been the vitiligo management pillar with capability of achieving main treatment outcomes; repigmentation and stabilization. Its stabilizing effect in dark skin debatable. However, randomized controlled trials regarding ability to control disease activity are lacking.To assess comparison systemic corticosteroids, mainstay stabilization, photo-types (III-V).This is a multicenter, placebo-controlled, randomized, prospective study. Eighty patients active nonsegmental (NSV)...
Background and Objectives Acne is a widespread disorder of the pilosebaceous unit. Isotretinoin background treatment cases severe acne. Side effects associated with standard 0.5–1 mg/kg/day dose decrease patient compliance. Pulsed dye laser (PDL) was proved effective in management inflammatory The focus to evaluate efficacy combining low‐dose isotretinoin (0.25 mg/kg/day) PDL comparison higher‐dose (0.5 as monotherapy for acne vulgaris. Study Design/Materials Methods current prospective...
Summary Background A poloxamer solution acting as a vehicle for the lipid base particulate system (cubosome dispersions) containing alpha lipoic acid ( ALA ) has achieved encouraging results in skin aging. Objective Evaluate efficacy of 5% Cubosomal an anti‐aging formulation. Methods This single‐blinded, placebo‐controlled, comparative study was conducted on 20 females. Patients were instructed to apply gel formulation active ingredient over right half their face and placebo left twice daily...
BACKGROUND Fractional CO 2 laser has been shown effective in improving pigmentation, pruritus, and tightness of hypertrophic burn scars. However, there is no consensus on the optimal treatment parameters. OBJECTIVE To compare effectiveness different densities fractional mature MATERIALS AND METHODS The study included 25 patients, each with 3 or more Scars were randomly assigned to low-, medium-, high-density laser. Each scar received sessions at 1-month interval. degree improvement was...
To investigate the therapeutic efficacy and safety of growth factors combined with fractional carbon dioxide (CO2 ) laser in comparison CO2 alone a sample patients facial mature burn scars.Fifteen Egyptian bilateral scars were treated six sessions at 6-week intervals. Following each session, topical cocktail was applied to one side face split-face manner. Clinical evaluation by Vancouver Scar Scale (VSS), Patient Observer Assessment (PSOS), photography before 2 months after last session...
Mycosis fungoides is the most common type of primary cutaneous T cell lymphomas. Doxycycline promoted apoptosis in different human malignant lines and vivo models.To test for therapeutic efficacy doxycycline comparison to PUVA early stages classic MF its effect on apoptosis.Thirty-six patients were randomized into either: 200 mg daily (n = 18) or (3 weekly sessions) 12 weeks. The outcome (therapeutic efficacy) was defined terms objective response rate (ORR) which measured according changes...
In spite of multiple therapeutic regimens for vitiligo, disease relapse remains a challenge. Most guidelines consider systemic treatments only in rapidly progressive with wider surface areas. This delay halting the immune attack, may give chance further progression as well establishment resident memory T-cell population predisposing to future relapses. To assess ability early therapy localized (<2% BSA), recent onset (<6 months) vitiligo control activity and minimize possibility recurrence....
ABSTRACTBackground Identifying migraine comorbidities may guide prognosis and treatment options. This study aimed to assess the frequency of comorbid conditions among adults with living in Greater Cairo.Methods In this cross-sectional study, Egyptian sufferers aged ≥ 18 years Cairo were consecutively recruited (April 2019 – April 2021). Following The International Classification Headache Disorders-third edition, diagnosis was confirmed, type defined as whether episodic or chronic, without...
One of the most commonly used and effective lines treatment in chronic skin diseases is phototherapy. A protocol Kasr Al-Ainy Phototherapy Unit has been proposed for different dermatological such as psoriasis, mycosis fungoides, vitiligo based on best current research-based guidelines experience phototherapy team. This cornerstone everyday practice we believe dermatologists dealing with their hospitals or clinics, can find it helpful applicable to get better results patients. In part 1,...