A5018730159- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- melanin and skin pigmentation
- Platelet Disorders and Treatments
- Hair Growth and Disorders
- Skin and Cellular Biology Research
- Skin Protection and Aging
- Dermatologic Treatments and Research
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- Sperm and Testicular Function
- Eosinophilic Disorders and Syndromes
- Psoriasis: Treatment and Pathogenesis
- Cancer and Skin Lesions
- Oral and gingival health research
- Genetic and rare skin diseases.
- Oral and Maxillofacial Pathology
- Pharmacological Effects of Natural Compounds
- Hedgehog Signaling Pathway Studies
- Cell Adhesion Molecules Research
- Veterinary Oncology Research
- Ear and Head Tumors
- Healthcare and Venom Research
Cairo University
2014-2024
Dubai Health Authority
2019
University Dermatology
2017
Keio University
2009-2015
Keio University Hospital
2011
Riyadh Armed Forces Hospital
1993
Abstract Background Acral lesions of vitiligo are usually resistant to conventional lines treatment as well surgical interventions. Objective To clarify causes underlying resistance acral pigmentation in by studying some the factors associated with mechanisms repigmentation following photochemotherapy. Methods The study included twenty patients active vitiligo. Skin biopsies were taken from lesional and perilesional skin areas expected respond (trunk proximal limb) areas, before after PUVA...
The anatomical, histological and morphological structure of the fasciomuscular tube which surrounds spermatic cord was studied in 20 cadavers full mature neonatal foetal death 10 varicocele patients. cremasteric fasciæ are composed elastic fibres impregnated with collagen, act as an stocking to cord. Together muscle they form a pump may play important role hæmodynamics venous return from Tubal atrophy subluxation were found varicocele. resulting inefficiency pumping mechanism is discussed...
ABSTRACT Oral erosions and ulcers of pemphigus vulgaris (PV) are a debilitating condition that is usually difficult to treat. The wound healing properties platelet‐rich plasma (PRP) encouraged us evaluate its usefulness in treatment non‐healing oral PV lesions. Seven patients with chronic PV, resistant conventional therapy, were treated weekly monthly injections PRP affected mucosal membranes. All recruits reported improvement pain mastication 6 7 had an disease area index scores treatment....
Summary Background Many studies have suggested a strong relation between diet and acne. patients with acne believe that spicy salty foods exacerbate Aim To assess the relationship dietary intake of food onset, severity, duration Methods Two hundred vulgaris 200 age‐ gender‐matched controls were subjected to detailed questionnaire taking, clinical examination assessment through using “24 h recall” method. Sodium content 24‐h was computed by computer program connecting participants'...
Melanocyte-keratinocyte suspension (M-K susp) is gaining popularity for vitiligo treatment. Few studies have addressed procedure-related variables.To assess the effect of different M-K susp variables on clinical outcome in stable vitiligo.This prospective multicenter comparative study included 40 cases with nonsegmental vitiligo. Donor site was either a skin graft noncultured epidermal cell (NCECS) or hair follicle units outer root sheath (ORSHFS). Recipient prepared by cryoblebbing CO2...
Background: Diagnosing cutaneous sarcoidosis and necrobiotic granulomas is challenging. Objective: Assessing the value of dermoscopy in differentiating from evaluating whether their dermoscopic features will be altered after treatment. Methods: Nineteen 11 granuloma patients (2 necrobiosis lipoidica, 4 annulare 5 rheumatoid nodule) were included this study. The diagnosis was confirmed by skin biopsy. lesions examined using non-contact polarized dermoscope (Dermlite 2 HR-Pro; 3Gen, San Juan...
Androgenetic alopecia (AGA) is the commonest form of hair loss in men. Alopecia areata (AA) an organ-specific autoimmune disease. Studies revealed that Dickkopf 1 (DKK-1), a powerful suppressor Wnt/β-catenin signaling pathway, induced anagen-to-catagen transition mice. Moreover, vitro studies suggested DKK-1 played role dihydrotestosterone (DHT)-induced balding.To evaluate tissue levels patients with AGA and AA, to assess its possible as pathogenetic mechanism both disorders.This study...
Background: The Autoimmune Bullous Disease Quality of Life (ABQOL) and the Treatment (TABQOL) questionnaires proved to be reliable tools that measure disease treatment burden. Objectives: We aimed assess ABQOL TABQOL in Arabic population. Methods: English were translated into language by a certified translation agency. Eighty autoimmune bullous (AIBD) patients included this study. Patients asked answer 2 questionnaires. After 1 week same again. Results: age ranged from 19 81 years (mean=46),...
Abstract The clinical phenotypes of pemphigus can be explained by the desmoglein (Dsg) compensation theory. However, some atypical cases such as cutaneous vulgaris ( cPV ), in which patients have anti‐Dsg3 antibodies without oral erosions, do not conform to this To explain discrepancy between and anti‐Dsg antibody profiles, pathogenic strength immunoglobulin (Ig)G autoantibodies against Dsg3 must taken into consideration. We analyzed epitopes blister‐inducing sera from three having IgG...
CXCL12 has an important role in skin homeostasis and inflammation.In this work, the expression of was evaluated psoriasis vulgaris, psoriatic arthritis (PsA) patients relation to disease activity methotrexate (MTX) therapy.Skin biopsies were obtained from 10 vulgaris patients, PsA 20 controls. The repeated 6 weeks after MTX therapy. stained immunohistochemically by stromal dermal factor 1 alpha (CXCL 12) antibody.Psoriatic showed significantly more CXCL 12 than before treatment but not...
Pemphigus vulgaris (PV) is an immunoglobulin G-mediated autoimmune bullous skin disease. Nonorgan-specific antibodies were detected in Tunisian and Brazilian pemphigus patients with different prevalence.Fifty PV fifty controls screened for antinuclear (ANAs), anti-smooth muscle (ASMAs), anti-parietal (APAs), anti-mitochondrial antibodies, Anti-nuclear cytoplasmic (ANCA) by indirect immunofluorescence.Thirty-nine female 11 male. Fifteen did not receive treatment before while 35 on systemic...
Abstract Epidermolysis bullosa acquisita ( EBA ) is an autoimmune subepidermal blistering disease caused by autoantibodies against type VII collagen. An enzyme‐linked immunosorbent assay ELISA currently available to detect in . There have been reports suggesting generically that indices reflect severity; however, there is, as yet, no conclusion whether fluctuate with activity over time each patient. This study aimed investigate titers and validate the clinical significance of checking values...
Addition of different growth factors to the medium used in autologous melanocyte-keratinocyte transplantation procedure (MKTP) was reported literature. The aim current study comparison response MKTP segmental vitiligo (SV) with and without adding suspension medium. Eighteen cases SV were randomly divided into two groups. In group A: Ham F12 for B: 5 ng/mL recombinant basic fibroblast factor (bFGF) 25 mg/500 mL 3′5′ cyclic adenosine monophosphate (cAMP) added All received NB-UVB twice weekly...