A5052005049- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Nanomaterials in Catalysis
- Topic Modeling
- Electrochemical sensors and biosensors
- Microfluidic and Capillary Electrophoresis Applications
- Metabolomics and Mass Spectrometry Studies
- Mitochondrial Function and Pathology
- Radical Photochemical Reactions
- Natural Language Processing Techniques
- Speech and dialogue systems
- Advanced Fluorescence Microscopy Techniques
- Carbon and Quantum Dots Applications
- Biosensors and Analytical Detection
- Modular Robots and Swarm Intelligence
- Nanoplatforms for cancer theranostics
- Intelligent Tutoring Systems and Adaptive Learning
- Prosthetics and Rehabilitation Robotics
- Optical Imaging and Spectroscopy Techniques
- Robotic Locomotion and Control
- Redox biology and oxidative stress
- Organic Light-Emitting Diodes Research
Hunan Institute of Technology
2016-2024
University of Science and Technology Beijing
2021-2024
Southwest University
2024
Shenzhen University
2022-2023
Technische Universität Braunschweig
2022
Tianjin University of Technology
2012-2022
China Electronics Technology Group Corporation
2020-2022
Harbin Institute of Technology
2018-2021
Zunyi Medical University
2021
Harbin University
2018-2020
Cysteine (Cys) is one of the most important essential biothiols in lysosomes. Highly selective probes for specific detection and imaging lysosomal Cys over other biological thiols are rare. Herein, we developed a lysosome-targeted near-infrared fluorescent probe SHCy-C based on novel NIR-emitting thioxanthene-indolium dye. Due to turn-on fluorescence response elicited by intramolecular charge transfer (ICT) processes before after reaction with Cys, exhibits high selectivity sensitivity (16...
Abstract Flexible organic materials that exhibit dynamic ultralong room temperature phosphorescence (DURTP) via photoactivation have attracted increasing research interest for their fascinating functions of reversibly writing-reading-erasing graphic information in the form a long afterglow. However, due to existence nonnegligible activation threshold initial exposure dose, display mode these has thus far been limited binary patterns. By resorting halogen element doping carbon dots (CDs)...
A fluorescent chemosensor with high sensitivity and selectivity for palladium species based on a conjugate of phosphine rhodamine B has been developed. The showed an excellent detection limit down to the 10−9 M range, which is lower than WHO content in drug chemicals.
Stimulated emission depletion (STED) microscopy holds tremendous potential and practical implications in the field of biomedicine. However, weak anti-bleaching performance remains a major challenge limiting application STED fluorescent probes. Meanwhile, main excitation wavelengths most reported probes were below 500 nm or above 600 nm, few them between 500-600 nm. Herein, we developed new tetraphenyl ethylene-functionalized rhodamine dye (TPERh) for mitochondrial dynamic cristae imaging...
In the rapidly evolving domain of question answering systems, ability to integrate machine comprehension with relational reasoning stands paramount. This paper introduces a novel architecture, Dependent Syntactic Semantic Augmented Graph Network (DSSAGN), designed address intricate challenges multi-hop answering. By ingeniously leveraging synergy between syntactic structures and semantic relationships within knowledge graphs, DSSAGN offers breakthrough in interpretability, scalability,...
A lysosome-targeted near-infrared (NIR) fluorescent probe <bold>SHCy-P</bold> for the detection and imaging of ACP in living cells has been designed developed.
A novel mitochondria-targeted fluorescent probe, <bold>MXS</bold>, with a large Stokes shift (130 nm) based on xanthene-hemicyanine dyad structure, has been successfully designed and synthesized for the specific detection of HOCl.
Considering the scarcity of palladium ion probes with subcellular organelle targeting, especially near-infrared (NIR) emission wavelength fluorophores, our group has been working to overcome this problem and looking forward providing potential practical tools for exploring toxicity ions at level. In paper, a novel colorimetric NIR fluorescent probe, BHCy-Pd, specific detection (Pd2+) in lysosomes via an internal charge-transfer (ICT) mechanism was designed synthesized. As expected, BHCy-Pd...
Near-infrared (NIR) dyes are of great interest in biomedicine due to diminished interfering absorption and fluorescence from biological samples, reduced scattering, enhanced tissue penetration depth. In this context, we report the synthesis rectilinearly π-extended rhodamine using a unique intramolecular nucleophilic substitution aromatic hydrogen (SNArH) strategy. The strategy makes use an SNArH reaction between preorganized amino nitrogen electron-deficient carbon xanthylium ion. presented...
Abstract We demonstrate an environmentally friendly one‐step soap‐free emulsion polymerization strategy to develop fluorescent carbazole‐based copolymer monodisperse microspheres for highly sensitive and selective detection of Fe 3+ . The feature a stable spherical morphology with narrow size distribution through regulating N ‐vinylcarbazole (NVCz) content (1.25–10.0 wt.%). Notably, the as‐made exhibit strong luminescence, tunable emission intensity specific surface areas. Interestingly,...
A new donor-two-acceptor modular fluorescence rotor DpCy7 involving a phenolate donor unit and two benzothiazolium acceptor moieties was designed synthesized. The underwent an internal charge transfer to form Cy7-like longer conjugated system fluorochrome at physiological pH. probe exhibited strong turn-on (8.5-fold) deep-red emission with larger Stokes shift in glycerol aqueous solutions restriction of rotation. Both the intensity lifetime displayed linear relationship viscosity changes...
The mitochondria-targeted fluorescence probe <bold>L</bold>, a thioxanthene-benzoindole derivative, for the detection and imaging of endogenous H<sub>2</sub>S in living cells cellular antioxidant stress has been developed.
Central injection and repetitive Smale horseshoe transformation for antisolvent precipitation enable continuous production of monodisperse nanoparticles with sizes less than 50 nm, while preventing contact lipid solution channel walls.