A5103179673- Circadian rhythm and melatonin
- Spaceflight effects on biology
- Neuroendocrine regulation and behavior
- Exercise and Physiological Responses
- Heart Rate Variability and Autonomic Control
- Genetics, Aging, and Longevity in Model Organisms
- Radiology practices and education
- Natural product bioactivities and synthesis
- Ubiquitin and proteasome pathways
- Ginseng Biological Effects and Applications
- Cardiovascular Health and Risk Factors
- S100 Proteins and Annexins
- Cholesterol and Lipid Metabolism
- Signaling Pathways in Disease
- Biological Stains and Phytochemicals
- Radiation Dose and Imaging
- Genetics and Neurodevelopmental Disorders
- Cardiovascular and exercise physiology
- Hormonal Regulation and Hypertension
- Light effects on plants
- Regulation of Appetite and Obesity
- Advanced X-ray and CT Imaging
- Adipokines, Inflammation, and Metabolic Diseases
- Endoplasmic Reticulum Stress and Disease
Cornell University
2012-2024
Peking University
2017
Second Affiliated Hospital of Xi'an Jiaotong University
2016
Kobe University
2005-2013
Brain (Germany)
2005
Jet-lag symptoms arise from temporal misalignment between the internal circadian clock and external solar time. We found that rhythms of behavior (locomotor activity), gene expression, body temperature immediately reentrained to phase-shifted light-dark cycles in mice lacking vasopressin receptors V1a V1b (V1a(-/-)V1b(-/-)). Nevertheless, V1a(-/-)V1b(-/-) was still coupled clock, which oscillated normally under standard conditions. Experiments with suprachiasmatic nucleus (SCN) slices...
To evaluate the effect of beinaglutide on weight loss and plasma protein patterns inflammation/obesity relevant cytokines biomarkers.This study involved 36 adult patients with a body mass index (BMI) ≥ 24 kg/m2 T2DM. Beinaglutide was administered for three months. Changes in weight, fasting glucose (FPG) level, 2 h postprandial (2h-PG) glycosylated hemoglobin (HbA1c) BMI visceral subcutaneous fat areas were measured at baseline after months treatment. In addition, biomarkers measured.After...
There is growing evidence that ubiquitin-proteasome system plays an important role for the generation of circadian rhythms in mice as Drosophila. Here we examined expression ubiquitin-related enzymes (Ubce5, UbcM4, Ube2v, Ube2d2, UchL1, UchL3, Ubp41, Ufd1L, β-TrCP) suprachiasmatic nucleus (SCN). At mRNA level, these were faint to moderate except ubiquitin carboxy-terminal hydrolase L1 (UchL1), a dominant deubiquitinating salvaging enzyme. Although strongly expressed SCN, UchL1 did not show...
Abstract Background Spatial disorientation is an early symptom of Alzheimer’s disease (AD). The hippocampus creates a cognitive map, wherein cells form firing fields in specific locations within environment, termed place cells. Critically, remain stable across visits to but change their rate or field location different environment. In rodent models AD‐like pathology, exhibit broadened tuning and altered responses environmental changes. Additionally, events known as sharp wave ripples (SWRs),...
Fatiguing exercise can produce oxidative stress in muscle, leading to the injury of muscle. We used electron spin resonance (ESR) techniques studied effects Verbascoside, extracted from Pedicularis, on antioxidative following fatiguing exercise. 70 rats were randomly divided into two groups, control and Verbascoside treatment group. The group fed with 3.2 mg/kg/day twice a day for ten days before ran exhaustion single bout protocol incremental intensity. Every 5 animals groups killed at each...