A5069444793- Nutrition and Health in Aging
- Frailty in Older Adults
- Cancer survivorship and care
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Sports injuries and prevention
- Exercise and Physiological Responses
- Aging, Health, and Disability
- Muscle metabolism and nutrition
- Nerve injury and regeneration
- Balance, Gait, and Falls Prevention
- Muscle Physiology and Disorders
- Gestational Diabetes Research and Management
- Neurogenesis and neuroplasticity mechanisms
- School Health and Nursing Education
- Sport Psychology and Performance
- Therapeutic Uses of Natural Elements
- Sex and Gender in Healthcare
- Basque language and culture studies
- Body Composition Measurement Techniques
- Geriatric Care and Nursing Homes
- Autophagy in Disease and Therapy
- Physical Activity and Health
University of the Basque Country
2015-2025
Biogipuzkoa Health Research Institute
2023
Onkologikoa
2019-2020
Centre National de la Recherche Scientifique
2019
Université de Bordeaux
2019
Flinders University
2017
OBJECTIVES To determine the effect of multicomponent exercise on frailty and related adverse outcomes in residents long‐term nursing homes (LTNHs). DESIGN A single‐blind randomized controlled trial. SETTING Ten LTNHs Gipuzkoa, Spain. PARTICIPANTS The study sample comprised 112 men women aged 70 years or older who scored 50 higher Barthel Index, 20 MEC‐35 test (an adapted validated version Mini‐Mental State Examination Spanish), were capable standing up walking independently for at least 10...
This study sought to determine the association of relative age and performance young elite basketball players. The distribution birth dates, heights, positions, classification male female participants (n = 2395) U16, U18 U20 European Basketball Championships were analysed. We found an over-representation players born during initial months year in all groups, with effect being more evident U16 than teams, particularly squads. Nevertheless, championships, those teams that had oldest performed...
Few studies have simultaneously examined changes in physical, cognitive and emotional performance throughout the aging process. Baseline data from an ongoing experimental randomized study were analyzed. Physical activity, handgrip, Senior Fitness Test, Trail Making Test A, Rey Auditory-Verbal Learning Quality of Life-Alzheimer's Disease Scale (QoL-AD) Goldberg Depression used to assess participants. Logistic regression models applied. Trial registration: ACTRN12616001044415 (04/08/2016). The...
<b><i>Background:</i></b> Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. <b><i>Objective:</i></b> To determine association serum concentration body composition, physical fitness, activity level, in long-term nursing home residents. We also aimed to ascertain effect an exercise program on levels....
Abstract Background Older adults with cancer experience negative long‐term functional effects of both and treatments. Exercise may minimize their age‐related cancer‐related decline. Methods We conducted a multicentre open‐label 12 month randomized clinical trial two parallel arms including participants aged ≥70 years lymphoma or carcinoma requiring curative treatment. The study started at the beginning any phase treatment (surgery, chemotherapy, radiotherapy). usual care group (UCG) received...
Abstract Background the potential benefits of dual-task interventions on older adults living in long-term nursing homes (LTNHs) from a multidimensional perspective are unknown. We sought to determine whether addition simultaneous cognitive training multicomponent exercise program offers further dual-task, physical and performance, psycho-affective status, quality life frailty LTNH residents. Design: single-blind randomized controlled trial. Setting nine LTNHs Gipuzkoa, Spain. Subjects 85 men...
ABSTRACT Aim To analyse the association between gender and in‐hospital mortality odds ratios among patients in Basque Country. Design Cross‐sectional study. Methods Admission data pertaining to period 1 January 2016 31 December 2018 were gathered for all registered acute care hospitals (both public private) Odds calculated through binomial logistic regressions determine each diagnostic category of ICD‐10. Results Women had a higher ratio diseases circulatory system (OR 1.07 [1.01–1.14], p...
The purpose of the Aging-ONDUAL-TASK study is to determine if a supervised dual-task program carried out in long-term nursing homes able attenuate frailty greater extent than same multicomponent exercise alone. This multicenter randomized controlled trial will include 188 participants who be randomly allocated either or with simultaneous cognitive training (dual-task training). Inclusion criteria are as follows: ≥ 70 years, 50 on Barthel Index, 20 Mini Examen Cognoscitivo (MEC-35) stand up...
There is increasing evidence suggesting that cognition and physical frailty interact within a cycle of decline associated with aging which has been called cognitive frailty. Exercise programs have demonstrated to be an effective tool prevent functional during aging, but little known about their potential restore or maintain functionality in individuals require long-term nursing care. Besides, WHO recently highlighted the importance introducing systematic musculoskeletal health for older...
Serum alpha-klotho (s-klotho) protein has been linked with lifespan, and low concentrations of s-klotho have associated worse physical cognitive outcomes. Although its significance in aging remains unclear, proposed as a molecular biomarker frailty dependence. This study is secondary analysis data from clinical trial performed population 103 older individuals living 10 nursing homes Gipuzkoa (Spain). We aimed to elucidate associations between (as measured by enzyme-linked immunosorbent...
Physical activity (PA) during pregnancy has positive health implications for both mother and child. However, current literature indicates that not all pregnant women meet the international recommendations PA (at least 150 min/week of moderate-to-vigorous PA). The main objective this study was to assess levels among in city Donostia-San Sebastian identify their sociodemographic predictors. We recruited 441 12th week from local public obstetric services. Women wore an accelerometer one two...
This study analyzed the effects of an individualized and progressive multicomponent exercise program on blood pressure, cardiorespiratory fitness, body composition in long-term care residents. was a single-blind, multicenter, randomized controlled trial performed 10 settings involved 112 participants. Participants were randomly assigned to control group or intervention group. The participated routine activities; six-month focused strength, balance, walking recommendations. maintained peak...
Given the increasing prevalence of frailty and its implications for public health, identification biomarkers to detect is essential. Sestrin-1 a protein with protective role in muscle function. This study aimed determine whether serum sestrin-1 concentration differed between frail non-frail populations investigate association frailty-related variables 225 older women men living nursing homes (Gipuzkoa, Spain). Serum was measured by ELISA. Frailty, dependence, anthropometry, physical...
Exercise interventions improve physical fitness, cognitive and affective function, quality of life among nursing home residents. However, little is known regarding the consequences cessation activity, or detraining. We analyzed activity level, life, loneliness during a 6-month observational follow-up after randomized controlled trial in which residents performed either routine activities (control group) group-based exercise (intervention group). The intervention group showed an important...
Angiotensin-converting enzyme (ACE) and angiotensin-converting 2 (ACE2) are two of the main components renin–angiotensin system (RAS). Imbalanced RAS showing lower ACE2 has been associated with increased cardiovascular risk, muscular pathologies, sarcopenia, frailty, other age-related pathologies a poorer health status. However, its role in aging remains unclear. Thus, aim this work was to analyze serum enzymatic activity ACE ACE2, ACE/ACE2 ratio association anthropometric parameters, blood...
To compare the capacity of blood myostatin concentration and physical, cognitive, affective function tests to predict frailty among long-term care (LTC) residents.This cross-sectional analysis used baseline data from three randomized controlled trials involving 260 older adults in 14 LTC centers. Serum levels were analyzed by enzyme-linked immunosorbent assay. Frailty, physical fitness, cognitive functions assessed using validated scales.The Timed Up Go, gait speed, 6-minute walk, Berg...