- Dementia and Cognitive Impairment Research
- Aging, Health, and Disability
- Alzheimer's disease research and treatments
- Autoimmune Neurological Disorders and Treatments
- Attention Deficit Hyperactivity Disorder
- Pharmaceutical Practices and Patient Outcomes
- Neurological Disorders and Treatments
- Traumatic Brain Injury Research
- Genetic Neurodegenerative Diseases
- Advanced Neuroimaging Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disease Mechanisms and Treatments
- Neurobiology of Language and Bilingualism
- Cholinesterase and Neurodegenerative Diseases
- Neurological disorders and treatments
- Folate and B Vitamins Research
- Health, Medicine and Society
- Cognitive Functions and Memory
- Pharmaceutical Economics and Policy
- Peripheral Neuropathies and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Prion Diseases and Protein Misfolding
- Infectious Diseases and Tuberculosis
- Management of metastatic bone disease
- Stress and Burnout Research
Favaloro University
2025
Hospital de Niños de la Santísima Trinidad
2016-2024
Favaloro Foundation
2018-2024
University of Buenos Aires
2021-2022
Mitre (United States)
2017-2021
Instituto de Neurología Cognitiva
2011-2020
Fundacion Favaloro Hospital Universitario
2020
Hospital Británico de Buenos Aires
2012-2019
Instituto de Neurología de Buenos Aires
2012-2015
Consejo Superior de Investigaciones Científicas
2014
ABSTRACT Background: Mild cognitive impairment (MCI) is a transitional state between normal aging and dementia. Identifying this condition would allow early interventions that may reduce the rate of progression to Alzheimer's disease (AD). We examined efficacy six-month intervention program (CIP) in patients with MCI assess patients’ at one-year follow-up. Methods: Forty-six participants assessed neuropsychological, neurological, neuropsychiatry, functional procedures were included study...
Purpose: this paper investigates the biomechanical effect of thermo-formed aligners equipped with complementary attachments (CBAs) on periodontal ligaments (PDL) during expansion process maxillary arch. The analysis was conducted using advanced simulations based finite element method (FEM). Methods: High-resolution 3D CAD models were created for four tooth types: canine (3), first premolar (4), second (5), and molar (6). Additional developed aligners, CBAs, PDLs. These integrated into a...
ABSTRACT Background: The economic cost of dementia is high and can be predicted by cognitive neuropsychiatric profiles. differential costs the various subtypes are unknown in Argentina, this study therefore aimed to compare these costs. Methods: Patients with a diagnosis Alzheimer-type (DAT), frontotemporal (FTD) vascular (VaD), their primary caregivers, were evaluated between 2002 2008. Results: 104 patients (DAT = 44, FTD 34, VaD 26) screened matched age educational level 29 healthy...
La Teoria de la Mente (ToM), termino propuesto por Premack y Woodruff en 1978, se refiere a capacidad para hacer inferencias sobre los estados mentales otros, implicando comprension prediccion conducta otras personas, sus conocimientos, intenciones creencias. El Test Mirada (TdlM) Baron-Cohen es uno instrumentos mas usados practica clinica evaluar las habilidades ToM diversas patologias como autismo sindrome Asperger, esquizofrenia demencias, entre otras. A pesar investigaciones, no hay...
ABSTRACT Background: "Forgetfulness" is frequent in normal aging and characteristic of the early stages dementia syndromes. The episodic memory test central for detecting amnestic mild cognitive impairment (MCI). Memory Binding Test (MBT) a simple, easy brief to detect stage impairment. Objective: To validate Argentine version MBT Latin American population estimate diagnostic accuracy as tool detection MCI. Methods: 88 subjects (46 healthy controls 42 patients with MCI) matched age...
Cognitive dysfunction may occur in 17-40% of patients with multiple system atrophy (MSA). It has been suggested a milder cognitive impairment cerebellar (MSA-C) than parkinsonian variant (MSA-P). However, differences profiles remain under discussion.To evaluate features series "probable MSA" from Argentina.After informed consent was obtained, an extensive tests battery administered. Nine (6 MSA-P and 3 MSA-C) composed the sample.Depression detected 43% patients. Seven showed at least one...
<strong>Background:</strong> Immunological causes of atypical parkinsonisms linked to neuronal specific antibodies have been recently reported. As these are potentially treatable disorders, it is desirable identify which clinical features may suggest an autoimmune etiology. <strong>Case Report:</strong> A 60-year-old-man with progressive supranuclear palsy associated anti-LGI-1 presented rapidly dementia and moaning. Treatment steroids immunoglobulin resulted in temporary improvement disease...
Abstract Background and Objectives In Argentina, government has established lockdown on 19 March 2020 to decrease SARS‐COV‐2 infection. The study aim was understand how mandatory quarantine imposed due COVID‐19 pandemic affected quality of life, mood, cognitive performance older adults with impairment. Design Longitudinal descriptive–observational study. Participants Patients impairment attending online training sessions. Measurements have completed by themselves Quality Life in Alzheimer's...
Hemichorea-hemiballism is a syndrome secondary to different etiologies. Drug-induced hemichorea rare related selective serotonin reuptake inhibitors. To the best of our knowledge, no previous cases associated with sertraline have been reported.A 65-year-old female noticed 1 week after initiation sertraline. After extensive investigations, other causes were excluded. Hemichorea remitted withdrawal.In patient, temporal association and negative clinical assessment supported diagnosis likely...
In its natural course, Alzheimer's disease involves the brain's White Matter (WM) microstructure, and WM of pathways carrying highly relevant information for cognitive performance. Diffusion-Tensor Imaging by Magnetic Resonance (DTI-MRI) enables measurement microstructure through Fractional Anisotropy (FA), Mean Diffusivity (MD). Objective: Using DTI-MRI, to assess involvement Corpus Callosum (CC), cingulum, other nerve pathways, both in healthy individuals patients with Disease Dementia...
Different areas of the medial temporal cortex are usually involved in Alzheimer's Disease (AD). Mean Diffusivity Magnetic Resonance Imaging (MD-MRI) measurements enable analysis water movements at tissue level, and increased diffusivity is associated with presence microstructure damages. Objective: To analyze MD-MRI cortex, both healthy controls patients degenerative amnesic Mild Cognitive Impairment (aMCI) Dementia (ADD). Forty-eight individuals (age 74.71±7.18 years) [16 control...
<strong>Background:</strong> Hemichorea–hemiballism is a syndrome secondary to different etiologies. Drug-induced hemichorea rare related selective serotonin reuptake inhibitors. To the best of our knowledge, no previous cases associated with sertraline have been reported. <strong>Case Report:</strong> A 65-year-old female noticed 1 week after initiation sertraline. After extensive investigations, other causes were excluded. Hemichorea remitted withdrawal. <strong>Discussion:</strong> In...