A5082045350- Pharmaceutical Practices and Patient Outcomes
- Global Cancer Incidence and Screening
- Patient Safety and Medication Errors
- Lung Cancer Diagnosis and Treatment
- Primary Care and Health Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare cost, quality, practices
- Heart Failure Treatment and Management
- Delphi Technique in Research
- Healthcare Quality and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Disease Management Strategies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Emergency and Acute Care Studies
- Global Health Workforce Issues
- COVID-19 and healthcare impacts
- Ocular Surface and Contact Lens
- Nursing Roles and Practices
- Pharmaceutical studies and practices
- Palliative Care and End-of-Life Issues
- Innovations in Medical Education
- Clinical practice guidelines implementation
- Amino Acid Enzymes and Metabolism
- Health Policy Implementation Science
- Healthcare Systems and Challenges
Royal College of Surgeons in Ireland
2013-2025
University of Medicine and Health Sciences
2022-2025
King's College London
2019-2024
University College Dublin
2023
John Wiley & Sons (United Kingdom)
2022-2023
University of Oxford
2023
Monash University
2023
University College Cork
2023
The University of Melbourne
2023
National Institute for Health Research
2020
Abstract Objective To determine whether hospital admission is associated with potentially inappropriate prescribing among older primary care patients (aged ≥65 years) and such was more likely after than before. Design Longitudinal study of retrospectively extracted data from general practice records. Setting 44 practices in Ireland 2012-15. Participants Adults aged 65 years or over attending participating practices. Exposure Admission to (any versus none, post-admission pre-admission). Main...
<ns3:p>Background Cancer is a leading cause of mortality in Ireland, accounting for approximately 30% deaths annually. Early diagnosis improves survival, reduces treatment burden, and enhances patient outcomes. Rapid Access Clinics (RACs) were introduced to facilitate expedited suspected lung, prostate, breast cancers, as well malignant melanoma. However, the extent which Irish general practitioners (GPs) utilise RAC pathways, subsequent diagnostic outcomes, remain poorly understood. Methods...
Abstract The impact of COVID‐19 has underlined the need for reliable information to guide clinical practice and policy. This urgency be balanced against disruption journal handling capacity continued ensure scientific rigour. We examined reporting quality highly disseminated research papers using a bibliometric analysis examining risk bias (RoB) amongst 250 top scoring Altmetric Attention Score (AAS) between January April 2020. Method‐specific RoB tools were used assess quality. After...
<ns4:p>Background Lung cancer remains a leading cause of cancer-related mortality, with early screening using low-dose computed tomography (LDCT) substantially improving survival. However, participation in programmes low, particularly among underserved populations. This review aims to identify barriers and facilitators the implementation lung within behavioural science framework, inform strategies that enhance community-based uptake. Methods hybrid systematic will be conducted two phases....
Objective There is limited evidence regarding the quality of prescribing for children in primary care. Several criteria (indicators) have been developed to assess appropriateness older and middle-aged adults but few are relevant children. The objective this study was develop a set indicators that can be applied or dispensing data sets determine prevalence potentially inappropriate (PIPc) care settings. Design Two-round modified Delphi consensus method. Setting Irish UK general practice....
The aim of this study was to survey GPs and community pharmacists (CPs) in Ireland regarding current practices medication management, specifically reconciliation, communication between health care providers errors as patients transition care. A national cross-sectional distributed electronically 2364 GPs, 311 GP Registrars 2382 CPs. Multivariable associations comparing CPs were generated content analysis free text responses undertaken. There an overall response rate 17.7% (897...
Background Sub‐optimal classification, interpretation and response to intrapartum electronic fetal monitoring using cardiotocography are known problems. Training is often recommended as a solution, but there lack of clarity about the effects training which type works best. Objectives Systematic review healthcare professionals in (PROSPERO protocol: CRD42017064525). Search strategy CENTRAL, Cochrane Library, MEDLINE, EMBASE, PsycINFO, British Nursing Database, CINAHL, ERIC, Scopus, Web...
Background Potentially inappropriate prescribing (PIP) is common in older adults and known to be associated with polypharmacy multimorbidity. Less about the prevalence causes of PIP middle-aged adults. Aim To determine predictors Design setting A repeated cross-sectional study was conducted using primary care data London. Method defined PRescribing Optimally Middle-aged People’s Treatments (PROMPT) criteria. Prescribing demographic were extracted from Lambeth DataNet (LDN), a pseudonymised...
Background Uncoded chronic kidney disease (CKD) is associated with poorer quality of care. Aim To ascertain the proportion and determinants CKD, which have not been formally recorded (Read coded), identify differences in management quality-of-care measures for patients coded uncoded CKD. Design setting Cross-sectional survey undertaken an ethnically diverse adult population using primary care electronic health records (EHRs) from GP clinics Lambeth, South London, UK. Method Multivariable...
Purpose: The viability and functions of the corneal epithelium are dependent in large measure on active uptake nutrients, growth factors, amino acids from stroma tear. present study presents cellular distribution(s) glutamate, Na+-dependent glutamate/aspartate transporters (excitatory acid transporters; EAAT1-5), Na+-independent glutamate/cystine exchanger (Xc− antiporter) subunits (xCT light chain 4F2hc heavy chain), glutamine synthetase (GS), γ-glutamyltranspeptidase (GGT) human...
The coronavirus disease 2019 (COVID-19) pandemic impacted cancer services worldwide. We examined the effect of first three waves on number electronic (e)-referrals to rapid access clinics (RACs) for breast, lung and prostate in Ireland.
Whether unintended discontinuation of common, evidence-based, long-term medication occurs after hospitalisation; what factors are associated with discontinuation; and whether the presence documentation at hospital discharge is continuity in general practice.Retrospective cohort study between 2012 2015.Electronic records supplied notifications 44 Irish practices.20 488 patients aged 65 years or more prescribed for chronic conditions.Discontinuity four evidence-based drug classes:...
Abstract Background Crowdsourcing engages the help of large numbers people in tasks, activities or projects, usually via internet. One application crowdsourcing is screening citations for inclusion a systematic review. There evidence that ‘Crowd’ non-specialists can reliably identify quantitative studies, such as randomized controlled trials, through assessment study titles and abstracts. In this feasibility study, we investigated crowd performance an online, topic-based citation-screening...
Background Antibiotic overuse is associated with antimicrobial resistance (AMR). It unclear whether community AMR driven by overall antibiotic use or high levels of repeated (intense) individual patients. Aim To determine the association between prescribing intensity (all prescriptions; any indication), and rates UTI among patients within small communities. Design & setting Repeated cross-sectional ecological analysis geographical areas (population averaging 1500) from 2012-2015 using...