- COVID-19 and healthcare impacts
- Cancer Immunotherapy and Biomarkers
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Treatments and Mutations
- COVID-19 and Mental Health
- Lung Cancer Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Suicide and Self-Harm Studies
- Global Health Workforce Issues
- Lung Cancer Research Studies
- Advanced Breast Cancer Therapies
- Vaccine Coverage and Hesitancy
- Healthcare professionals’ stress and burnout
- Cancer survivorship and care
- Brain Metastases and Treatment
- Psychology of Moral and Emotional Judgment
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Testicular diseases and treatments
- Forgiveness and Related Behaviors
- Artificial Intelligence in Healthcare and Education
- Death Anxiety and Social Exclusion
- Healthcare cost, quality, practices
- Medication Adherence and Compliance
- Mental Health via Writing
Mater Misericordiae University Hospital
2020-2024
Cork University Hospital
2022-2023
University College Cork
2022-2023
Clemson University
2021-2023
Royal College of Surgeons in Ireland
2016
In recent years the terms time and financial toxicities have entered vocabulary of cancer care. We would like to introduce another toxicity: climate toxicity. Climate toxicity is a double-edge sword in Increasing risk by exposure carcinogens, consequently increasing treatment requirements leads ever growing damage our environment. This article assesses impact change on patients, caused both healthcare workers facilities, suggests actions that may be taken mitigate them.
Research has confirmed there is a silver lining to many aversive experiences and that negative occurrences can be an opportunity for post-traumatic growth (PTG). To investigate benefit-finding in the COVID-19 crisis, 179 MTurk workers were surveyed. Participants reported dips satisfaction with work, leisure, fitness, mental health, finances midst of pandemic, relative 6 months prior future. Benefit-finding was significantly related PTG, coping, gratitude, health. The most common benefits...
The aim of this study was to survey GPs and community pharmacists (CPs) in Ireland regarding current practices medication management, specifically reconciliation, communication between health care providers errors as patients transition care. A national cross-sectional distributed electronically 2364 GPs, 311 GP Registrars 2382 CPs. Multivariable associations comparing CPs were generated content analysis free text responses undertaken. There an overall response rate 17.7% (897...
Background. Declared a "public health threat of international concern" by the World Health Organization, COVID-19 virus has caused deaths over half million individuals in United States just first 23 months after detection. The vaccine recently been introduced to reduce this public threat. However, due, part, rapidity with which was developed, many display hesitancy. Purpose. current study examined utility Protection Motivation Theory (PMT) predicting intentions receive vaccine. Method. One...
The COVID-19 pandemic has resulted in radical changes the delivery of healthcare worldwide. Our oncology service (at an Irish national cancer centre) rapidly transitioned to use telemedicine or virtual clinics (VC) minimise potential risk exposure amongst immunosuppressed, high-risk population. study aimed evaluate VC this setting.An 18-point questionnaire was designed investigate patient experience during Ireland and compliance with guidelines developed conduct role future. Questionnaires...
In a 2003 study, we examined five antecedents of school shootings – history rejection, acute rejection experience, psychological problems, fascination with death or violence, and guns. three studies, the current project role these factors in 57 K-12 shootings, 24 college/university 77 mass that occurred since original study. Over half all shooters had problems. More than college displayed rejection. However, more experienced an such as workplace firing. The characteristics identified study...
PURPOSE Cyberattacks are increasing in health care and cause immediate disruption to patient care, have a lasting impact, compromise scientific integrity of affected clinical trials. On the May 14, 2021, Irish service was victim nationwide ransomware attack. Patient disrupted across 4,000 locations, including 18 cancer trials units associated with Cancer Trials Ireland (CTI). This report analyses impact cyberattack on organization proposes steps mitigate future cyberattacks. METHODS A...
Abstract Introduction Early discontinuation of endocrine therapy (ET) is higher among patients with early breast cancer (EBC) compared to metastatic hormone receptor-positive (HR+) (MBC). In our clinical experience the reasons for this may include a significant burden ET side effects impacting quality life (QOL) in EBC. We hypothesized that QOL lower HR + EBC MBC on ET. Methods conducted cross-sectional observational study assess utilizing FACT-ES & EORTC QLQ C30 tools and receiving...
Around 30% of patients with breast cancer will develop brain metastases (BM). We sought to characterize the disease course, treatments and outcome for our patient cohort.We extracted clinicopathological data from electronic records January 2015 December 2020. Results were generated using SPSS statistics v27.We identified 98 patients. Median overall survival (OS) BM diagnosis was 3 months [hormone receptor (HR)+/human epidermal growth factor 2 (HER2)-], 8 [HR+/HER2+], 7 [HR-/HER2+] [triple...
Variants of COVID-19 have sparked controversy regarding mask and/or vaccine mandates in some sectors the country. Many people hold polarized opinions about such mandates, and it is uncertain what predicts attitudes towards these protective behavior mandates. Through a snow-ball sampling procedure respondents on social media platforms, this study examined skepticism 774 toward as function Protection Motivation Theory (PMT) health. Hierarchical linear regressions (PM) predictor mandate...
TPS355 Background: Locoregional therapies for hepatocellular carcinoma, such as transcatheter arterial chemoembolization (TACE) or ablation, can induce a peripheral anti-tumor immune response. This may be amplified by checkpoint inhibitors (ICI). Early and higher anti-CTLA4 dosing could potentially lead to better priming stronger Recent data has suggested that early (day 1 only), increased doses of therapy, was associated with encouraging clinical activity tolerable safety profile. study...
Objective: We aimed to use SARS-CoV-2 antibody tests assess the asymptomatic seroprevalence of individuals in high-risk hospital cohorts who's previous COVID-19 exposure is unknown; staff, and patients requiring haemodialysis or chemotherapy after first wave. Methods: In a single Center, study participants had five done simultaneously; one rapid diagnostic test (RDT) (Superbio Colloidal Gold IgM/IgG), four laboratory (Roche Elecsys® Anti-SARS-CoV-2 IgG [RE], Abbott Architect i2000SR [AAr],...
451 Background: TACE induces a peripheral anti-tumor immune response, which may be amplified by checkpoint inhibitors (ICI). Combining with dual ICI therapy has been shown to safe and feasible. Recent data suggested that Day 1-only anti-CTLA4 dosing could potentially lead stronger response tolerable safety profile though this novel schedule not previously combined TACE. Methods: Patients HCC (Childs Pugh A/B7, Barcelona clinic liver cancer stage B/C; ECOG 0/1; sorafenib-naive or experienced)...
<h3>Background</h3> Locoregional therapies for hepatocellular carcinoma, such as transcatheter arterial chemoembolization (TACE) or ablation, can induce a peripheral anti-tumor immune response. This may be amplified by checkpoint inhibitors (ICI). Early and higher anti-CTLA4 dosing could potentially lead to better priming stronger Recent data has suggested that early (Day 1 only), increased doses of therapy, was associated with encouraging clinical activity tolerable safety profile. study...
Background: External compression, thrombosis, or stenosis of the superior vena cava can lead to syndrome, a diagnosis that should be considered swiftly in patients presenting with classic symptoms such as facial and neck swelling, plethora, distended veins. Case Presentation: We report case acute port-a-cath associated thrombosis longstanding, previously uncomplicated vascular access device patient stable ER+/PR+/HER2+ metastatic breast cancer. After initial treatment, there was limited...
Background: Adjuvant chemotherapy has been an integral component of breast cancer care for decades. Advances in supportive have made, but despite this, infective complications therapy remain a significant toxicity concern. Case Presentation: A premenopausal patient presented to the emergency department during third wave Covid-19 pandemic with sepsis after second course adjuvant docetaxel-cyclophosphamide chemotherapy. Overnight she developed tetraplegia. An urgent MRI cervical spine revealed...